miRTarBase - #MIRT709878


—
pre-miRNA Information
pre-miRNA hsa-mir-4763   
Genomic Coordinates chr22: 46113566 - 46113657
Description Homo sapiens miR-4763 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4763-5p
Sequence 19| CGCCUGCCCAGCCCUCCUGCU |39
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs374776264 1 dbSNP
rs1174502793 2 dbSNP
rs966122637 3 dbSNP
rs891363409 6 dbSNP
rs1303008773 8 dbSNP
rs1446379219 11 dbSNP
rs1410535134 13 dbSNP
rs1424733379 14 dbSNP
rs1372551711 16 dbSNP
rs756995936 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TRAF1   
Synonyms EBI6, MGC:10353
Description TNF receptor associated factor 1
Transcript NM_005658   
Expression
Putative miRNA Targets on TRAF1
3'UTR of TRAF1
(miRNA target sites are highlighted)		 
>TRAF1|NM_005658|3'UTR
   1 GGTGGGCGGGGCTCCTGAGGGAGCTCCAACTCAGAAGGGAGCTAGCCAGAGGACTGTGATGCCCTGCCCTTGGCACCCAA
  81 GACCTCAGGGCACAAAGATGGGTGAAGGCTGGCATGATCCAAGCAAGACTGAGGGGTCGACTTCGGGCTGGCCATCTGGT
 161 TAGGATGGCAGGACGTGGGCTGGGCCCACAAAGGCAAAGGGTCCAGAAGGAGACAGGCAGAGCTGCTCCCCTCTGCACGG
 241 ACCATGCGACACTGGGAGGCCAGTGAGCCACTCCGGCCCCGAATGTTGAGGTGGACTCTCACCAAATGAGAAGAAAATGG
 321 AACCAGGCTTGGAACCGTAGGACCCAAGCAGAGAAGCTCTCGGGCTAGGAAGATCTCTGCAGGGCCGCCAGGGAGACCTG
 401 GACACAGGCCTGCTCTCTTTTTCTCCAGGGTCAGAAACAGGACCGGGTGGAAGGGATGGGGTGCCAGTTTGAATGCAGTC
 481 TGTCCAGGCTCGTCATTGGAGGTGAACAAGCAAACCCAGACGGCTCCACTAGGACTTCAAATTGGGGGTTGGATTTGAAG
 561 ACTTTTAAGTTTCCTTCCAGCCCAGAAAGTCTCTCATTCTAGGCCTCCTGGCCCAGGTGAGTCCTAGAGCTACAGGGGTT
 641 CTGGAAACATTCAGGAGCTTCCTGTCCTCCCAGCTCCTCACTCACCTTCAGTAACCCCCACTGGACTGACCTGGTCCACA
 721 GGGCACCTGCCACCCTGGGCCTGGCAGCTCAGCTTCCCCAACACGCAGGAGCACACCCAGCCCCCACATCCTGTGCCTCC
 801 ATCAGCTAAACACCACGTCACTTCATGCAGGTGAAACCCAGTCACTGTGAGCTCCCAGGTGCAGCCAGAGGCACCTCAAG
 881 AAGAAGAGGGGCATAAACTTTCCTCTTCCTGCCTAGAGGCCCCACCTTTGGTGCTTTCCAGAATCCCGTAACACCTGATT
 961 AACTGAGGCATCCACTTCTTTCAGCAGACTGATCAGGACCTCCAAGCCACTGAGCAATGTATAACCCCAAAGAAATAATT
1041 TTTAGAATCTCTTTCGAAGTTTTCCTAAAGTGTATGGTTTGGGAGTTGTTTGTACTGAGCCAGGTTTGAAAAGGCCATTG
1121 CTGAGTTTGAGGTGGTGCCACCAGTTTTGCAGGTGGCATCAGAGGCTGGCATGCTGGCAGGAACATCCCCTCTTAGCCCC
1201 AGTCTTCTCTTTTCTATAATGAGACCCACCCCAGCTTGCCTCCCTCCCTGGCTTCTCTGACCCTCAAAGGAGATGCCACG
1281 CAGGACAGACTGGAGAGAGAAGCCTGGGCAATACTGCCCGCCTGTCATGGCCTGGTGGTGGCCCACACCTATCTTCTCAC
1361 CTTGGAGGCCACACCCAACTTTCCAAAGACCCTGAGACAAGTCAGGACCCTACTACTCTCCCCTGCTGCTTTCCTGACAG
1441 CTTACTCTTCCTCCACCTGCTGAGCCTGTGCCAGACTCCATTGCTCAAATCGTTAGGGTTGCTTCTATAAAAATGGGTCA
1521 GTAGCCCTTCCTGTTCTCTCCAGCCCAGCATACAGGAGGATCAAAGGAGGTGACGGAGCATCGTGGCACGGCAGTCTCAA
1601 TGGGTCAGAAACCCAGGCCAGCTGGGCTCTAAGCCTGGCATCCTGTCATGCTTAGTCCTTCAGCTGAAGATCAGAGGAAG
1681 CCTCTCCCTTGCCCTCTCCAGCTCTAGGGGTTTTCAGGAGGCCCAACTGCAATAATGGAGCACTAGTGCTTTTATGTGCA
1761 ATGGTGTCGTCCATGCACGACAGCAGCAAACATTCTGGGGCTGCTTTTTATTGTTCCCACGGCTGACAGCGTGGCAGCGG
1841 AGACTGTGGAGGCAGTGGAGACTGACTTCTTCCTGCTGACAGCTGGATGTCACACATGAAGGTCTGGCCTAGCGAGTGAT
1921 GGGTCTAGGCCCTGAAACTGATGTCCTAGCAATAACCTCTTGATCCCTACTCACCGAGTGTTGAGCCCAAGGGGGGATTT
2001 GTAGAACAAGCCCCCATGAGAAACAGCTGTTACTCTACACTTTTGATTGCCTATTTCTGATGGCAAGAGATACATACTCT
2081 CTTCAAAGAGCATGAGATGCAGCCATTCTTTCAGCAAAGCTTCATTGACACCTGCACCTGTTAACTGTGTTCGACATTGA
2161 AGGGAGAAAGGCAAGATGTGCACTCTGGACTCAAGAAACTCTTAGTTCAGTGGAGGAAATGAGCAGATAAGTAGATCATT
2241 ATGATTGAGAGTAGGAGAAGCTTAGAGAAAGCACAGAATCCCAGATCCAGCTGGTGAAGGAGGGAAGGCTTCAGGCCTTT
2321 AAGCTCAGCCTGAGAATATTGTGAAATGCAGAGGATGGGGAAAAGGGAAGAGTACCGACTTGAAAACGGAGAGCTGTCTT
2401 GGCTGAGGGCAGGGTCTGTGTGGCAGGATGGGGGAGGGAGTCAGAAGGGTCAGATGAACTGGAGTGTAGACAGCATCAGA
2481 TGCAGCAGTGCCCACCGCCCCCCCCCCCACCCCCCGCCCTGCCCACAGAGCACCTGCTGGTAACCCTGGGCCTATTGAAA
2561 GCAGGATGAGATGATAATTTAAGACACTGAATGATTTCTTTTCCAACAAAGCTCTATGTTAAGTGCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucgUCC--UCCC-GAC---CCGUCCgc 5'
             |||  |||| |||   ||||||  
Target 5' ctgAGGGCAGGGTCTGTGTGGCAGGat 3'
 2403 - 2429 140.00 -21.80
2 
miRNA  3' ucgUCCUCCCG-AC--CCGUCCgc 5'
             |||  ||| ||  ||||||  
Target 5' cagAGGCTGGCATGCTGGCAGGaa 3'
 1160 - 1183 136.00 -19.10
3 
miRNA  3' ucgUCCUC--CCGA--CCCGUCCGc 5'
             |||:|  | ||  |||| ||| 
Target 5' ctgAGGGGTCGACTTCGGGCTGGCc 3'
 129 - 153 126.00 -17.61
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30182428 6 COSMIC
COSN31561527 7 COSMIC
COSN30485755 34 COSMIC
COSN30529844 104 COSMIC
COSN31611497 119 COSMIC
COSN15660675 164 COSMIC
COSN32064133 212 COSMIC
COSN28851128 238 COSMIC
COSN15660674 369 COSMIC
COSN15660673 372 COSMIC
COSN17076462 486 COSMIC
COSN5242095 722 COSMIC
COSN24741987 803 COSMIC
COSN32117957 883 COSMIC
COSN2309402 1028 COSMIC
COSN26318972 1447 COSMIC
COSN1372877 1778 COSMIC
COSN14758433 2279 COSMIC
COSN22496241 2507 COSMIC
COSN14788435 2508 COSMIC
rs2241003 521 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs182800215 3 dbSNP
rs377215261 4 dbSNP
rs755138990 5 dbSNP
rs1325432736 6 dbSNP
rs751639209 7 dbSNP
rs768598718 8 dbSNP
rs1335942621 11 dbSNP
rs758612772 17 dbSNP
rs1443909308 18 dbSNP
rs944961084 19 dbSNP
rs1376897403 24 dbSNP
rs765617631 25 dbSNP
rs200688324 27 dbSNP
rs754378117 30 dbSNP
rs1172315725 32 dbSNP
rs1454536468 38 dbSNP
rs764539781 43 dbSNP
rs562913449 48 dbSNP
rs371928914 50 dbSNP
rs1351951661 55 dbSNP
rs1310653557 56 dbSNP
rs544794951 58 dbSNP
rs777021590 59 dbSNP
rs1230000665 63 dbSNP
rs1294711484 66 dbSNP
rs1413651652 69 dbSNP
rs145874830 75 dbSNP
rs1221815637 77 dbSNP
rs1008143166 81 dbSNP
rs929429360 84 dbSNP
rs562361943 86 dbSNP
rs1304047534 90 dbSNP
rs1248593322 97 dbSNP
rs540975916 100 dbSNP
rs1451209504 115 dbSNP
rs1186800641 122 dbSNP
rs890806877 123 dbSNP
rs920680442 129 dbSNP
rs1451628219 135 dbSNP
rs1031047368 138 dbSNP
rs1167167678 139 dbSNP
rs999303264 141 dbSNP
rs1366869546 144 dbSNP
rs73662463 145 dbSNP
rs1321578622 146 dbSNP
rs780148216 147 dbSNP
rs1433485572 148 dbSNP
rs1012394793 153 dbSNP
rs1360658378 154 dbSNP
rs1228329298 156 dbSNP
rs927123821 172 dbSNP
rs980450286 174 dbSNP
rs771074309 175 dbSNP
rs1382774777 183 dbSNP
rs895316356 187 dbSNP
rs1414498401 188 dbSNP
rs1241665689 191 dbSNP
rs1186142884 193 dbSNP
rs1183615855 200 dbSNP
rs1474987426 207 dbSNP
rs1257036403 210 dbSNP
rs1254361127 214 dbSNP
rs1056649293 215 dbSNP
rs939564774 216 dbSNP
rs1485184091 217 dbSNP
rs57674795 223 dbSNP
rs1414618700 225 dbSNP
rs527558013 232 dbSNP
rs1456166167 234 dbSNP
rs567353033 238 dbSNP
rs920697543 239 dbSNP
rs1032776689 240 dbSNP
rs1304043125 242 dbSNP
rs974820521 245 dbSNP
rs963905897 246 dbSNP
rs1232340989 247 dbSNP
rs1340694172 253 dbSNP
rs1226273110 255 dbSNP
rs1314324437 264 dbSNP
rs999925820 269 dbSNP
rs911025631 271 dbSNP
rs1379960441 273 dbSNP
rs575321275 274 dbSNP
rs12379910 275 dbSNP
rs1254170085 276 dbSNP
rs535649558 280 dbSNP
rs1017760915 283 dbSNP
rs999626900 291 dbSNP
rs1416625848 298 dbSNP
rs967722951 302 dbSNP
rs1458730883 306 dbSNP
rs1356917688 316 dbSNP
rs374688234 331 dbSNP
rs752910534 336 dbSNP
rs781487955 337 dbSNP
rs567955941 338 dbSNP
rs531910861 343 dbSNP
rs111966050 349 dbSNP
rs929314703 357 dbSNP
rs899142586 358 dbSNP
rs1461179143 359 dbSNP
rs563175281 361 dbSNP
rs189678455 362 dbSNP
rs1347235464 365 dbSNP
rs1056534070 374 dbSNP
rs1277067727 386 dbSNP
rs1482175996 387 dbSNP
rs371422156 387 dbSNP
rs1204320777 392 dbSNP
rs886718000 399 dbSNP
rs534630221 407 dbSNP
rs1397901786 415 dbSNP
rs566494261 419 dbSNP
rs1479324183 423 dbSNP
rs775770844 426 dbSNP
rs1261665748 427 dbSNP
rs1394933614 429 dbSNP
rs546434615 432 dbSNP
rs1168615609 443 dbSNP
rs12379904 444 dbSNP
rs1039147081 445 dbSNP
rs943396575 449 dbSNP
rs763437527 450 dbSNP
rs1273022377 456 dbSNP
rs1370100599 458 dbSNP
rs1271737647 459 dbSNP
rs1229274735 464 dbSNP
rs17848033 469 dbSNP
rs17848034 472 dbSNP
rs949884371 478 dbSNP
rs1291125562 485 dbSNP
rs917180418 491 dbSNP
rs986605743 492 dbSNP
rs1356617750 499 dbSNP
rs1266803799 500 dbSNP
rs955222424 502 dbSNP
rs186796164 504 dbSNP
rs978950382 507 dbSNP
rs1166955813 519 dbSNP
rs2241003 521 dbSNP
rs1406903401 522 dbSNP
rs1437269993 524 dbSNP
rs1018227497 529 dbSNP
rs1393700366 538 dbSNP
rs1435701801 544 dbSNP
rs968153710 544 dbSNP
rs1009067628 555 dbSNP
rs1324981910 561 dbSNP
rs1021876384 562 dbSNP
rs1011968059 568 dbSNP
rs1387075073 570 dbSNP
rs890588453 580 dbSNP
rs1285015222 590 dbSNP
rs959086535 592 dbSNP
rs1391767594 593 dbSNP
rs1272910489 594 dbSNP
rs1330480113 596 dbSNP
rs1211107518 600 dbSNP
rs529485201 601 dbSNP
rs1026535861 602 dbSNP
rs1444781845 611 dbSNP
rs1191787197 613 dbSNP
rs1034718268 619 dbSNP
rs993686773 633 dbSNP
rs1004141897 636 dbSNP
rs899194944 637 dbSNP
rs1037652953 638 dbSNP
rs1161291832 642 dbSNP
rs1382623515 643 dbSNP
rs1002734128 653 dbSNP
rs905279366 655 dbSNP
rs1165173243 658 dbSNP
rs1342529125 660 dbSNP
rs1460640780 661 dbSNP
rs1046884232 663 dbSNP
rs1372620058 674 dbSNP
rs1293117067 683 dbSNP
rs867645908 685 dbSNP
rs562015382 686 dbSNP
rs1027015410 695 dbSNP
rs1451940962 699 dbSNP
rs778585852 700 dbSNP
rs1193437158 701 dbSNP
rs995063669 706 dbSNP
rs183278022 708 dbSNP
rs1204079992 714 dbSNP
rs1053049926 718 dbSNP
rs1443844600 723 dbSNP
rs1039031685 727 dbSNP
rs139890149 729 dbSNP
rs925646300 733 dbSNP
rs890574181 736 dbSNP
rs1274803469 739 dbSNP
rs964688431 742 dbSNP
rs1362019557 745 dbSNP
rs1229890022 747 dbSNP
rs191087999 764 dbSNP
rs146120386 765 dbSNP
rs954892109 766 dbSNP
rs1233739470 771 dbSNP
rs923791464 778 dbSNP
rs978415937 781 dbSNP
rs749753325 782 dbSNP
rs1433165803 786 dbSNP
rs540641049 790 dbSNP
rs573318339 791 dbSNP
rs1312501901 812 dbSNP
rs946630769 813 dbSNP
rs1026421632 815 dbSNP
rs914921268 816 dbSNP
rs963589794 817 dbSNP
rs993739238 817 dbSNP
rs1324901869 821 dbSNP
rs1016889394 837 dbSNP
rs768501309 838 dbSNP
rs959010279 841 dbSNP
rs1326573709 850 dbSNP
rs1346517243 857 dbSNP
rs1208031287 861 dbSNP
rs1389956263 874 dbSNP
rs371732383 879 dbSNP
rs1483154458 887 dbSNP
rs1207079888 888 dbSNP
rs1248118915 888 dbSNP
rs1418487018 894 dbSNP
rs1034768983 896 dbSNP
rs981874278 898 dbSNP
rs186886612 903 dbSNP
rs1199484508 909 dbSNP
rs1452672066 917 dbSNP
rs1173028432 918 dbSNP
rs1308728793 919 dbSNP
rs554611471 926 dbSNP
rs78184609 931 dbSNP
rs1046495274 934 dbSNP
rs1396219970 938 dbSNP
rs1387643917 945 dbSNP
rs1173612840 947 dbSNP
rs1369367323 948 dbSNP
rs1231482246 949 dbSNP
rs1302022552 951 dbSNP
rs1342491092 954 dbSNP
rs1229136126 955 dbSNP
rs995517500 968 dbSNP
rs1170333267 969 dbSNP
rs1480189177 974 dbSNP
rs574271537 989 dbSNP
rs62580170 991 dbSNP
rs899388542 994 dbSNP
rs895682309 997 dbSNP
rs1017859846 999 dbSNP
rs1193143163 1008 dbSNP
rs1180087787 1017 dbSNP
rs1007589148 1022 dbSNP
rs1052935172 1026 dbSNP
rs890459510 1047 dbSNP
rs1458758429 1055 dbSNP
rs1052316020 1056 dbSNP
rs1392965855 1061 dbSNP
rs1440785590 1065 dbSNP
rs775481287 1066 dbSNP
rs552783429 1074 dbSNP
rs1365281254 1085 dbSNP
rs934729490 1092 dbSNP
rs902361693 1095 dbSNP
rs1306508814 1098 dbSNP
rs1042194123 1100 dbSNP
rs534577253 1101 dbSNP
rs772127134 1104 dbSNP
rs367678874 1106 dbSNP
rs1332660914 1109 dbSNP
rs990692506 1115 dbSNP
rs937711281 1119 dbSNP
rs1466322756 1120 dbSNP
rs927596957 1122 dbSNP
rs1261342003 1129 dbSNP
rs1277615929 1132 dbSNP
rs1237987087 1141 dbSNP
rs1350106558 1149 dbSNP
rs987261649 1158 dbSNP
rs10985086 1162 dbSNP
rs1411873551 1165 dbSNP
rs1461435863 1183 dbSNP
rs1160559056 1187 dbSNP
rs1373749936 1193 dbSNP
rs1391396044 1196 dbSNP
rs919459852 1200 dbSNP
rs950474112 1203 dbSNP
rs762536292 1211 dbSNP
rs559396709 1214 dbSNP
rs1396238634 1215 dbSNP
rs773319207 1227 dbSNP
rs1353336285 1232 dbSNP
rs1232395986 1233 dbSNP
rs963479845 1244 dbSNP
rs1318614017 1247 dbSNP
rs1026913911 1248 dbSNP
rs1260195406 1257 dbSNP
rs1483732779 1261 dbSNP
rs1016530635 1263 dbSNP
rs1255584943 1269 dbSNP
rs1475092516 1273 dbSNP
rs769786579 1279 dbSNP
rs963523476 1280 dbSNP
rs1183964603 1286 dbSNP
rs1156390008 1303 dbSNP
rs1344089387 1308 dbSNP
rs1314345947 1316 dbSNP
rs146311959 1319 dbSNP
rs1013712843 1320 dbSNP
rs1288715914 1324 dbSNP
rs1375510587 1334 dbSNP
rs1210193114 1335 dbSNP
rs1444078501 1341 dbSNP
rs1281981899 1348 dbSNP
rs1007807909 1356 dbSNP
rs1312848776 1363 dbSNP
rs1213042161 1364 dbSNP
rs1278485642 1377 dbSNP
rs1485443577 1385 dbSNP
rs1206363112 1391 dbSNP
rs892553832 1396 dbSNP
rs4836834 1397 dbSNP
rs569201192 1398 dbSNP
rs904324743 1414 dbSNP
rs1454354369 1418 dbSNP
rs1174933820 1434 dbSNP
rs1392926059 1438 dbSNP
rs1269749550 1440 dbSNP
rs1308467783 1441 dbSNP
rs1356056185 1453 dbSNP
rs551030011 1456 dbSNP
rs903296394 1457 dbSNP
rs1043516829 1459 dbSNP
rs781396139 1462 dbSNP
rs893630685 1465 dbSNP
rs1347490368 1466 dbSNP
rs1283685475 1471 dbSNP
rs1275301238 1474 dbSNP
rs1448759223 1483 dbSNP
rs1342811115 1485 dbSNP
rs575050003 1491 dbSNP
rs1436444972 1492 dbSNP
rs1316798721 1499 dbSNP
rs1457159617 1500 dbSNP
rs888815876 1502 dbSNP
rs1470200366 1505 dbSNP
rs747371016 1507 dbSNP
rs1392712673 1509 dbSNP
rs1161824015 1514 dbSNP
rs1453489317 1516 dbSNP
rs933109959 1526 dbSNP
rs1421123879 1532 dbSNP
rs1459600609 1533 dbSNP
rs1169433904 1554 dbSNP
rs1412550494 1557 dbSNP
rs1350438843 1564 dbSNP
rs1442980224 1566 dbSNP
rs1324047793 1569 dbSNP
rs181912447 1574 dbSNP
rs568638347 1575 dbSNP
rs942222281 1576 dbSNP
rs1187894727 1583 dbSNP
rs909353967 1589 dbSNP
rs1249720006 1590 dbSNP
rs981076604 1591 dbSNP
rs1211527385 1594 dbSNP
rs141422251 1606 dbSNP
rs780437848 1618 dbSNP
rs1289372790 1619 dbSNP
rs1337660933 1623 dbSNP
rs1212358592 1625 dbSNP
rs1252844082 1641 dbSNP
rs1228989645 1645 dbSNP
rs1046039197 1655 dbSNP
rs992164986 1661 dbSNP
rs754530773 1674 dbSNP
rs575712937 1679 dbSNP
rs1243518276 1680 dbSNP
rs1474204318 1681 dbSNP
rs528751082 1686 dbSNP
rs1185763521 1687 dbSNP
rs1418288324 1700 dbSNP
rs956656276 1707 dbSNP
rs1162722450 1709 dbSNP
rs1031102729 1713 dbSNP
rs1358627279 1716 dbSNP
rs1320337531 1722 dbSNP
rs928953722 1726 dbSNP
rs866538027 1732 dbSNP
rs1366543181 1736 dbSNP
rs41273402 1766 dbSNP
rs1007509319 1768 dbSNP
rs546221542 1769 dbSNP
rs766029203 1778 dbSNP
rs889028859 1779 dbSNP
rs1205246462 1781 dbSNP
rs1285718962 1784 dbSNP
rs115072725 1787 dbSNP
rs563165916 1792 dbSNP
rs986385054 1795 dbSNP
rs541894316 1807 dbSNP
rs1476078216 1812 dbSNP
rs897472894 1817 dbSNP
rs758024515 1820 dbSNP
rs144148638 1821 dbSNP
rs1160431034 1826 dbSNP
rs114871824 1831 dbSNP
rs1249738381 1835 dbSNP
rs149526410 1837 dbSNP
rs948209656 1838 dbSNP
rs576666927 1839 dbSNP
rs1413354078 1842 dbSNP
rs1011580249 1848 dbSNP
rs1293028309 1852 dbSNP
rs1351698256 1855 dbSNP
rs558809680 1862 dbSNP
rs536971682 1866 dbSNP
rs1241789344 1869 dbSNP
rs1280850392 1870 dbSNP
rs1247048525 1877 dbSNP
rs138153294 1881 dbSNP
rs1203987796 1885 dbSNP
rs1002091095 1888 dbSNP
rs1280639709 1902 dbSNP
rs918169672 1908 dbSNP
rs906481440 1913 dbSNP
rs1271046161 1914 dbSNP
rs79031413 1916 dbSNP
rs753486107 1923 dbSNP
rs929028946 1925 dbSNP
rs1343507740 1928 dbSNP
rs1469708732 1931 dbSNP
rs918910487 1935 dbSNP
rs1397157273 1942 dbSNP
rs979539262 1952 dbSNP
rs1037464755 1956 dbSNP
rs1312715578 1959 dbSNP
rs750118145 1965 dbSNP
rs1397649997 1974 dbSNP
rs941723175 1975 dbSNP
rs910735852 1976 dbSNP
rs1335647130 1977 dbSNP
rs1238846815 1979 dbSNP
rs986326027 1980 dbSNP
rs191396802 1982 dbSNP
rs955025646 1987 dbSNP
rs1232582510 1989 dbSNP
rs1279088316 1990 dbSNP
rs1480842507 1993 dbSNP
rs1367393179 1995 dbSNP
rs10985085 2001 dbSNP
rs7037154 2007 dbSNP
rs1030224382 2010 dbSNP
rs997370787 2016 dbSNP
rs1254950194 2019 dbSNP
rs547177270 2030 dbSNP
rs1022004210 2038 dbSNP
rs1173253370 2040 dbSNP
rs1035980927 2045 dbSNP
rs1391968137 2047 dbSNP
rs528689655 2051 dbSNP
rs990211070 2053 dbSNP
rs1044788268 2062 dbSNP
rs1442270810 2065 dbSNP
rs1326076958 2069 dbSNP
rs958755361 2074 dbSNP
rs1438012174 2080 dbSNP
rs1300188491 2087 dbSNP
rs1034384942 2088 dbSNP
rs1229388494 2092 dbSNP
rs1249377619 2094 dbSNP
rs571005219 2095 dbSNP
rs1317281652 2096 dbSNP
rs1214238429 2101 dbSNP
rs1002018828 2118 dbSNP
rs146983626 2125 dbSNP
rs141258727 2131 dbSNP
rs918065017 2138 dbSNP
rs1024925824 2140 dbSNP
rs1191563563 2142 dbSNP
rs1056754327 2145 dbSNP
rs1479137571 2152 dbSNP
rs564867979 2153 dbSNP
rs897493379 2169 dbSNP
rs1037348172 2181 dbSNP
rs941662803 2188 dbSNP
rs1483395435 2189 dbSNP
rs775389619 2195 dbSNP
rs1362280269 2226 dbSNP
rs979840416 2231 dbSNP
rs1293257084 2234 dbSNP
rs373319834 2245 dbSNP
rs911304290 2249 dbSNP
rs1220993694 2253 dbSNP
rs1050170015 2257 dbSNP
rs1261375732 2263 dbSNP
rs933537982 2265 dbSNP
rs1487012231 2271 dbSNP
rs1208726104 2278 dbSNP
rs9886724 2279 dbSNP
rs1302427193 2281 dbSNP
rs3196386 2287 dbSNP
rs777072034 2295 dbSNP
rs977702304 2303 dbSNP
rs1370764008 2318 dbSNP
rs1475153091 2323 dbSNP
rs541427140 2331 dbSNP
rs760995183 2339 dbSNP
rs1371916618 2350 dbSNP
rs1286769043 2353 dbSNP
rs1310541399 2354 dbSNP
rs1359458024 2359 dbSNP
rs11330036 2365 dbSNP
rs1294879200 2367 dbSNP
rs529700016 2376 dbSNP
rs138713838 2377 dbSNP
rs568421957 2387 dbSNP
rs1318831900 2388 dbSNP
rs1034436946 2394 dbSNP
rs1417044563 2403 dbSNP
rs867690079 2408 dbSNP
rs1006306744 2412 dbSNP
rs981925303 2415 dbSNP
rs1486101391 2426 dbSNP
rs150105516 2428 dbSNP
rs1025191639 2430 dbSNP
rs993448151 2431 dbSNP
rs897763404 2432 dbSNP
rs1410723391 2435 dbSNP
rs774187317 2436 dbSNP
rs1180129938 2439 dbSNP
rs1016168854 2444 dbSNP
rs1420377422 2447 dbSNP
rs1483211106 2448 dbSNP
rs1257057444 2453 dbSNP
rs1005927839 2461 dbSNP
rs1206378019 2463 dbSNP
rs1212708013 2464 dbSNP
rs1045237888 2470 dbSNP
rs1373401033 2481 dbSNP
rs983375072 2486 dbSNP
rs1446947121 2487 dbSNP
rs1298704808 2491 dbSNP
rs951580835 2494 dbSNP
rs1011981497 2496 dbSNP
rs1029928975 2497 dbSNP
rs1056640339 2498 dbSNP
rs924192843 2499 dbSNP
rs1290921202 2500 dbSNP
rs1235132010 2501 dbSNP
rs1055895 2502 dbSNP
rs79683243 2503 dbSNP
rs75803656 2504 dbSNP
rs888774147 2505 dbSNP
rs879579163 2506 dbSNP
rs868735971 2507 dbSNP
rs13053 2508 dbSNP
rs1275538674 2509 dbSNP
rs1468558069 2509 dbSNP
rs867915145 2509 dbSNP
rs879814436 2509 dbSNP
rs1322790664 2510 dbSNP
rs1421381336 2510 dbSNP
rs1477477231 2510 dbSNP
rs28615117 2513 dbSNP
rs186200404 2515 dbSNP
rs1463107270 2516 dbSNP
rs946224077 2516 dbSNP
rs914850737 2517 dbSNP
rs558503902 2519 dbSNP
rs1431749272 2524 dbSNP
rs543665094 2534 dbSNP
rs937377604 2543 dbSNP
rs927266663 2544 dbSNP
rs1272081201 2549 dbSNP
rs1360332652 2554 dbSNP
rs985976448 2558 dbSNP
rs981553622 2562 dbSNP
rs971865590 2563 dbSNP
rs73543780 2593 dbSNP
rs1215070030 2598 dbSNP
rs1209690278 2615 dbSNP
rs972330362 2617 dbSNP
rs1330781561 2618 dbSNP
rs1450745988 2624 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124A_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + A HITS-CLIP data was present in Chi_124B_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + B HITS-CLIP data was present in Chi_ControlA_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control A HITS-CLIP data was present in Chi_ControlB_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control B ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_124A_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + A
Location of target site ENST00000373887.3 | 3UTR | GGGGGAGGCAAGAUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset Chi_124B_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + B
Location of target site ENST00000373887.3 | 3UTR | GGGGGAGGCAAGAUGCAGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset Chi_ControlA_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control A
Location of target site ENST00000373887.3 | 3UTR | GGGGGAGGCAAGAUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset Chi_ControlB_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control B
Location of target site ENST00000373887.3 | 3UTR | GGGGGAGGCAAGAUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
69 hsa-miR-4763-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT116035 DEPDC1 DEP domain containing 1 2 2
MIRT347197 SIN3B SIN3 transcription regulator family member B 2 2
MIRT443248 C9orf170 chromosome 9 open reading frame 170 2 2
MIRT475164 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT495486 VTI1B vesicle transport through interaction with t-SNAREs 1B 2 2
MIRT496755 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT496863 C21orf2 chromosome 21 open reading frame 2 2 2
MIRT499264 NBPF11 NBPF member 11 2 2
MIRT499517 MAFK MAF bZIP transcription factor K 2 2
MIRT512952 MKI67 marker of proliferation Ki-67 2 2
MIRT514656 NUP93 nucleoporin 93 2 2
MIRT517986 SLC16A13 solute carrier family 16 member 13 2 2
MIRT522816 KLHL9 kelch like family member 9 2 4
MIRT525495 CD63 CD63 molecule 2 2
MIRT528111 FOXH1 forkhead box H1 2 2
MIRT531683 MYO3A myosin IIIA 2 2
MIRT534806 RAB37 RAB37, member RAS oncogene family 2 2
MIRT573041 SHMT1 serine hydroxymethyltransferase 1 2 2
MIRT576720 Wars tryptophanyl-tRNA synthetase 2 2
MIRT609727 MLXIPL MLX interacting protein like 2 2
MIRT610843 FAM180B family with sequence similarity 180 member B 2 4
MIRT614735 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT616981 EPOR erythropoietin receptor 2 2
MIRT617265 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT619405 INTS7 integrator complex subunit 7 2 2
MIRT621832 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT621893 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT630263 SMIM14 small integral membrane protein 14 2 2
MIRT634879 SENP8 SUMO/sentrin peptidase family member, NEDD8 specific 2 2
MIRT636863 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT637653 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT637699 ZNF439 zinc finger protein 439 2 2
MIRT637759 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT638193 TAOK1 TAO kinase 1 2 2
MIRT638996 ADO 2-aminoethanethiol dioxygenase 2 2
MIRT642221 RABAC1 Rab acceptor 1 2 2
MIRT643327 ATCAY ATCAY, caytaxin 2 4
MIRT643419 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT644499 RNF14 ring finger protein 14 2 2
MIRT644603 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT644795 C21orf59 chromosome 21 open reading frame 59 2 2
MIRT648732 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT653856 SHE Src homology 2 domain containing E 2 2
MIRT654129 RPL14 ribosomal protein L14 2 4
MIRT658876 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT671624 C20orf144 chromosome 20 open reading frame 144 2 4
MIRT677367 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT677579 TRIM65 tripartite motif containing 65 2 2
MIRT678220 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT679613 RRP36 ribosomal RNA processing 36 2 2
MIRT686081 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT691817 ICA1L islet cell autoantigen 1 like 2 2
MIRT693869 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT694544 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694926 ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2 2
MIRT697758 USP37 ubiquitin specific peptidase 37 2 2
MIRT697891 UBE2B ubiquitin conjugating enzyme E2 B 2 2
MIRT701569 MYPN myopalladin 2 2
MIRT703081 GPRIN3 GPRIN family member 3 2 2
MIRT708104 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT708320 NT5C 5', 3'-nucleotidase, cytosolic 2 2
MIRT709878 TRAF1 TNF receptor associated factor 1 2 2
MIRT713545 GJB1 gap junction protein beta 1 2 2
MIRT716275 NUP85 nucleoporin 85 2 2
MIRT716621 CRCP CGRP receptor component 2 2
MIRT717987 C9orf171 cilia and flagella associated protein 77 2 2
MIRT718438 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT722544 AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2 2
MIRT724013 F2RL1 F2R like trypsin receptor 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4763 Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Doxorubicin 31703 NSC123127 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Fluorouracil 3385 NSC19893 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Vincristine 5978 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4763 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4763-5p Anthracycline 30323 NSC82151 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Fluorouracil 3385 NSC19893 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Cyclophosphamide 2907 NSC26271 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Methotrexate 126941 NSC740 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Taxol 36314 NSC125973 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-4763-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4763-5p Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-4763-5p Platinum 23939 sensitive tissue (non-small cell lung cancer)
hsa-miR-4763-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4763-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4763-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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