pre-miRNA Information
pre-miRNA hsa-mir-6769b   
Genomic Coordinates chr1: 206474803 - 206474864
Description Homo sapiens miR-6769b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6769b-3p
Sequence 42| CCCUCUCUGUCCCACCCAUAG |62
Evidence Experimental
Experiments Meta-analysis
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26671848 9 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs555627187 3 dbSNP
rs782102173 4 dbSNP
rs201952639 7 dbSNP
rs782001154 9 dbSNP
rs1488064450 15 dbSNP
rs782111367 16 dbSNP
rs370859899 18 dbSNP
rs1305197911 19 dbSNP
Putative Targets

Gene Information
Gene Symbol LHX5   
Synonyms -
Description LIM homeobox 5
Transcript NM_022363   
Expression
Putative miRNA Targets on LHX5
3'UTR of LHX5
(miRNA target sites are highlighted)
>LHX5|NM_022363|3'UTR
   1 GGCCGCCGGGCCGCCCCCCGCGCTCGGCCCCCGGGGGCCCCGCCCCGAAGCAGCCTCCTGAAACCAAAACGCCCGACGCA
  81 GACGCGGTGGGAGACGTGGGTGTCCCTCGGGGGTTCTCTCTCGGGTCCGCACTCAACTGGCAGCTGCTCCTCGGCTGGGC
 161 GCCGAGGGGGGGCCGACCCCCATCTCCACCCCGCGGGCTCTCCAGGAGCCTCAGCCCACCGCCAGTACTCTCCCAGCAAC
 241 CGCGAGCAATTTCTTGGGACCAAAGTCAATACTCCGGAGGGTCAAGAGATTTCGAGCACGC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' gauaCCCACCC-UG--UCUCUCCc 5'
              || |||| :|  ||:|:|| 
Target 5' cctcGGCTGGGCGCCGAGGGGGGg 3'
149 - 172 123.00 -21.10
2
miRNA  3' gauacCCACCCUG-UCUCUccc 5'
               || ||| | |||||   
Target 5' actccGGAGGGTCAAGAGAttt 3'
271 - 292 116.00 -11.62
3
miRNA  3' gauacCCACCCUGUCUCUCCc 5'
               ||||    :|||| | 
Target 5' gacgcGGTG----GGAGACGt 3'
81 - 97 98.00 -11.14
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30510218 37 COSMIC
COSN30116979 46 COSMIC
COSN15662635 47 COSMIC
COSN21114724 171 COSMIC
COSN25070841 460 COSMIC
COSN8695330 569 COSMIC
COSN26780516 587 COSMIC
COSN23736458 813 COSMIC
COSN5930802 1049 COSMIC
COSN20317786 1098 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1406853181 1 dbSNP
rs1234036576 2 dbSNP
rs982749841 4 dbSNP
rs955460312 5 dbSNP
rs769149666 6 dbSNP
rs1468469158 9 dbSNP
rs1405590228 10 dbSNP
rs1171635180 13 dbSNP
rs1430661857 14 dbSNP
rs1418003351 15 dbSNP
rs1186390689 18 dbSNP
rs1029775747 19 dbSNP
rs1448373662 22 dbSNP
rs1470191960 24 dbSNP
rs1243176652 25 dbSNP
rs1204985029 26 dbSNP
rs1405668561 28 dbSNP
rs1459741767 31 dbSNP
rs951234979 32 dbSNP
rs996926563 33 dbSNP
rs1305662041 34 dbSNP
rs1262114417 36 dbSNP
rs1204960761 37 dbSNP
rs1308978089 38 dbSNP
rs1403402378 39 dbSNP
rs1221644204 41 dbSNP
rs1293376477 42 dbSNP
rs1336472152 45 dbSNP
rs1213874818 46 dbSNP
rs1277802080 47 dbSNP
rs900040385 57 dbSNP
rs1034773852 70 dbSNP
rs1181162758 70 dbSNP
rs981939774 83 dbSNP
rs1460638065 95 dbSNP
rs566094144 96 dbSNP
rs1033143081 100 dbSNP
rs971498371 101 dbSNP
rs1023425298 111 dbSNP
rs1230612856 114 dbSNP
rs140791986 115 dbSNP
rs1164120889 116 dbSNP
rs1228067223 118 dbSNP
rs1422483418 125 dbSNP
rs1000863871 127 dbSNP
rs1162941804 129 dbSNP
rs1397510275 129 dbSNP
rs893420502 132 dbSNP
rs903418298 133 dbSNP
rs1376177479 138 dbSNP
rs534405195 140 dbSNP
rs1357789248 142 dbSNP
rs12319643 143 dbSNP
rs1244485667 144 dbSNP
rs1252197534 150 dbSNP
rs945070292 152 dbSNP
rs1197126294 153 dbSNP
rs1270346155 160 dbSNP
rs1456929704 166 dbSNP
rs182980779 167 dbSNP
rs1338931877 168 dbSNP
rs1244872654 169 dbSNP
rs903355163 171 dbSNP
rs1396235351 172 dbSNP
rs35666719 173 dbSNP
rs540536231 173 dbSNP
rs868588507 173 dbSNP
rs899581458 174 dbSNP
rs551735433 175 dbSNP
rs936145800 176 dbSNP
rs1056652728 181 dbSNP
rs542884724 182 dbSNP
rs536685694 190 dbSNP
rs1161180197 192 dbSNP
rs926450096 193 dbSNP
rs1046967503 196 dbSNP
rs1296761137 197 dbSNP
rs1328555362 199 dbSNP
rs973896643 202 dbSNP
rs574009589 218 dbSNP
rs941268976 221 dbSNP
rs1316812548 230 dbSNP
rs1203782397 235 dbSNP
rs1264418408 241 dbSNP
rs981963980 247 dbSNP
rs908435259 257 dbSNP
rs1262237993 261 dbSNP
rs1430078450 262 dbSNP
rs1191350274 266 dbSNP
rs971911381 267 dbSNP
rs1416867660 272 dbSNP
rs1423152590 275 dbSNP
rs982678068 276 dbSNP
rs955386046 278 dbSNP
rs569651611 281 dbSNP
rs1403931972 288 dbSNP
rs1466032937 289 dbSNP
rs975906078 293 dbSNP
rs1277909852 294 dbSNP
rs957376712 299 dbSNP
rs1223676760 300 dbSNP
rs1284657139 301 dbSNP
rs1032974237 314 dbSNP
rs964128643 315 dbSNP
rs1033608838 316 dbSNP
rs1000346175 318 dbSNP
rs1289465465 323 dbSNP
rs866804703 323 dbSNP
rs924812120 324 dbSNP
rs1360275257 325 dbSNP
rs977651237 328 dbSNP
rs1214206750 330 dbSNP
rs1237197624 332 dbSNP
rs1335349856 333 dbSNP
rs1308224493 337 dbSNP
rs950306272 342 dbSNP
rs1427373684 359 dbSNP
rs1020525311 361 dbSNP
rs1014452693 363 dbSNP
rs1160537047 365 dbSNP
rs896197255 366 dbSNP
rs998348319 386 dbSNP
rs1452216345 399 dbSNP
rs1297979631 403 dbSNP
rs1056092438 408 dbSNP
rs1366521744 412 dbSNP
rs1364328745 413 dbSNP
rs899611815 418 dbSNP
rs1303058277 424 dbSNP
rs1002367946 438 dbSNP
rs1385709712 440 dbSNP
rs904909820 441 dbSNP
rs1318686244 455 dbSNP
rs375708457 456 dbSNP
rs1237779881 457 dbSNP
rs1038628027 460 dbSNP
rs1046704316 470 dbSNP
rs1359888026 470 dbSNP
rs888119186 470 dbSNP
rs1245182048 472 dbSNP
rs929933240 476 dbSNP
rs1177887014 478 dbSNP
rs1252676109 480 dbSNP
rs1438399485 487 dbSNP
rs1158558711 492 dbSNP
rs1386321136 492 dbSNP
rs1426909348 493 dbSNP
rs1165135434 495 dbSNP
rs1347778286 500 dbSNP
rs927884288 502 dbSNP
rs1298252191 503 dbSNP
rs1374799904 508 dbSNP
rs941197085 514 dbSNP
rs1383324882 527 dbSNP
rs1247931831 530 dbSNP
rs1463457593 533 dbSNP
rs1046688305 537 dbSNP
rs1321354462 538 dbSNP
rs1205419227 540 dbSNP
rs1253205284 543 dbSNP
rs1456495902 545 dbSNP
rs908361832 546 dbSNP
rs947924761 552 dbSNP
rs1244267716 556 dbSNP
rs756916877 560 dbSNP
rs557265053 563 dbSNP
rs1413436831 567 dbSNP
rs1404406878 572 dbSNP
rs530008939 575 dbSNP
rs1355817386 576 dbSNP
rs1463590494 577 dbSNP
rs1330036709 582 dbSNP
rs1406777274 583 dbSNP
rs559271036 585 dbSNP
rs975411380 588 dbSNP
rs964494562 589 dbSNP
rs977419146 604 dbSNP
rs967648703 605 dbSNP
rs146449424 610 dbSNP
rs1198113618 617 dbSNP
rs1490482229 618 dbSNP
rs755291734 623 dbSNP
rs998818657 627 dbSNP
rs964244268 634 dbSNP
rs571349317 638 dbSNP
rs565412008 639 dbSNP
rs1475929860 651 dbSNP
rs967555704 656 dbSNP
rs1020409180 668 dbSNP
rs766730447 669 dbSNP
rs1261529292 679 dbSNP
rs1014460632 683 dbSNP
rs1476615212 684 dbSNP
rs1344034160 685 dbSNP
rs960245072 696 dbSNP
rs115283008 701 dbSNP
rs1406104566 703 dbSNP
rs543303573 706 dbSNP
rs904838789 710 dbSNP
rs1325005885 711 dbSNP
rs1038151309 712 dbSNP
rs35997156 716 dbSNP
rs1358402531 725 dbSNP
rs1431167248 731 dbSNP
rs1290362329 732 dbSNP
rs1005297126 743 dbSNP
rs561337240 748 dbSNP
rs1325739911 753 dbSNP
rs1383875264 761 dbSNP
rs1046896964 764 dbSNP
rs144024513 770 dbSNP
rs1046328433 782 dbSNP
rs1218426104 788 dbSNP
rs1261398006 793 dbSNP
rs1487112171 797 dbSNP
rs1192466738 799 dbSNP
rs1429461500 800 dbSNP
rs1478706169 801 dbSNP
rs947925555 802 dbSNP
rs1424401157 806 dbSNP
rs922521347 808 dbSNP
rs572739617 814 dbSNP
rs1426982053 816 dbSNP
rs7954435 817 dbSNP
rs114124246 820 dbSNP
rs1303975002 821 dbSNP
rs936111554 824 dbSNP
rs1248357559 825 dbSNP
rs1191209659 827 dbSNP
rs1274296620 832 dbSNP
rs866415277 833 dbSNP
rs925940646 836 dbSNP
rs190328204 838 dbSNP
rs1284397215 844 dbSNP
rs967398302 856 dbSNP
rs115076324 858 dbSNP
rs1269125817 860 dbSNP
rs1341761663 862 dbSNP
rs922553542 870 dbSNP
rs992926530 873 dbSNP
rs1196169954 874 dbSNP
rs558197623 874 dbSNP
rs536773866 877 dbSNP
rs544508572 887 dbSNP
rs1321618134 893 dbSNP
rs1262933121 894 dbSNP
rs760379467 898 dbSNP
rs1034628598 900 dbSNP
rs1418845615 906 dbSNP
rs139118711 915 dbSNP
rs969114679 916 dbSNP
rs984234526 923 dbSNP
rs952491898 934 dbSNP
rs116588605 936 dbSNP
rs1005308346 937 dbSNP
rs548206311 956 dbSNP
rs1436862095 957 dbSNP
rs1025028036 958 dbSNP
rs1358030808 958 dbSNP
rs1207635490 967 dbSNP
rs114607918 972 dbSNP
rs750083699 974 dbSNP
rs1180474292 980 dbSNP
rs551332932 988 dbSNP
rs1236312129 996 dbSNP
rs1470123631 1001 dbSNP
rs1183978522 1005 dbSNP
rs1369925718 1008 dbSNP
rs1053644422 1010 dbSNP
rs1162887361 1013 dbSNP
rs1397354126 1018 dbSNP
rs936479117 1030 dbSNP
rs571120797 1031 dbSNP
rs998043328 1032 dbSNP
rs1453925861 1035 dbSNP
rs900990658 1039 dbSNP
rs1039661140 1040 dbSNP
rs942611324 1047 dbSNP
rs186209979 1049 dbSNP
rs904527317 1050 dbSNP
rs1318114621 1051 dbSNP
rs1373745148 1055 dbSNP
rs1043000904 1061 dbSNP
rs180940461 1068 dbSNP
rs1190534632 1071 dbSNP
rs1460187631 1074 dbSNP
rs1457276257 1077 dbSNP
rs35768537 1079 dbSNP
rs946146440 1084 dbSNP
rs1440452388 1085 dbSNP
rs558192108 1085 dbSNP
rs1204782846 1086 dbSNP
rs565097552 1088 dbSNP
rs1271239843 1092 dbSNP
rs1470620037 1092 dbSNP
rs911460541 1092 dbSNP
rs1227811442 1098 dbSNP
rs1400562738 1105 dbSNP
rs1363611834 1107 dbSNP
rs1395784306 1107 dbSNP
rs71443037 1107 dbSNP
rs1214533688 1108 dbSNP
rs984308163 1108 dbSNP
rs1275824811 1114 dbSNP
rs952899737 1119 dbSNP
rs1340618045 1122 dbSNP
rs375432542 1122 dbSNP
rs992852753 1134 dbSNP
rs550251094 1135 dbSNP
rs534812873 1142 dbSNP
rs536645862 1144 dbSNP
rs972464005 1144 dbSNP
rs927445550 1145 dbSNP
rs1380212054 1152 dbSNP
rs1024682600 1157 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_ControlB_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control B ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' gauacccaccCUGUCUCUCCc 5'
                    || ||||||| 
Target 5' ------gauuGAAAGAGAGGg 3'
1 - 15
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_ControlB_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control B
Location of target site ENST00000261731.3 | 3UTR | GAUUGAAAGAGAGGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
209 hsa-miR-6769b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT181753 UHMK1 U2AF homology motif kinase 1 2 2
MIRT287119 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT395372 CDC42EP4 CDC42 effector protein 4 2 4
MIRT472533 NACC1 nucleus accumbens associated 1 2 4
MIRT472611 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT482405 ADRB1 adrenoceptor beta 1 2 10
MIRT492330 SETD1B SET domain containing 1B 2 2
MIRT499238 VAV3 vav guanine nucleotide exchange factor 3 2 6
MIRT512274 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT534548 RUNX1 runt related transcription factor 1 2 2
MIRT535374 PEX5L peroxisomal biogenesis factor 5 like 2 2
MIRT535424 PDZD8 PDZ domain containing 8 2 2
MIRT539329 AHSA2 activator of HSP90 ATPase homolog 2 2 4
MIRT569350 EFHC1 EF-hand domain containing 1 2 2
MIRT576116 Klf6 Kruppel-like factor 6 2 2
MIRT607241 LINS lines homolog 1 2 4
MIRT607364 ASAH2 N-acylsphingosine amidohydrolase 2 2 4
MIRT609572 CATSPER4 cation channel sperm associated 4 2 2
MIRT610045 SERPINA3 serpin family A member 3 2 2
MIRT610284 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT610302 KLHL21 kelch like family member 21 2 2
MIRT610393 FOXE1 forkhead box E1 2 2
MIRT610432 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT610510 BARHL2 BarH like homeobox 2 2 2
MIRT611818 FCRL4 Fc receptor like 4 2 2
MIRT612755 MYOCD myocardin 2 2
MIRT613698 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT613917 POU3F1 POU class 3 homeobox 1 2 2
MIRT615153 URGCP-MRPS24 URGCP-MRPS24 readthrough 2 2
MIRT615201 CLUAP1 clusterin associated protein 1 2 2
MIRT615338 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT616706 UBXN2A UBX domain protein 2A 2 2
MIRT617186 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT617526 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT617596 NUDT5 nudix hydrolase 5 2 4
MIRT617763 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT618613 SHOX short stature homeobox 2 2
MIRT619301 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619515 TXLNB taxilin beta 2 2
MIRT619925 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT619942 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT620025 NFAM1 NFAT activating protein with ITAM motif 1 2 2
MIRT620554 C10orf10 chromosome 10 open reading frame 10 2 4
MIRT620752 CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) 2 2
MIRT621798 TMEM233 transmembrane protein 233 2 2
MIRT621843 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT622693 PLSCR1 phospholipid scramblase 1 2 2
MIRT622733 PITPNM3 PITPNM family member 3 2 2
MIRT623004 ONECUT3 one cut homeobox 3 2 2
MIRT623211 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT623771 GPR37L1 G protein-coupled receptor 37 like 1 2 2
MIRT624119 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT624150 DIAPH1 diaphanous related formin 1 2 2
MIRT624443 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT624855 ABI2 abl interactor 2 2 2
MIRT625311 SHISA6 shisa family member 6 2 2
MIRT625741 MTSS1 MTSS1, I-BAR domain containing 2 2
MIRT626292 ZNF85 zinc finger protein 85 2 2
MIRT627400 TMEM170A transmembrane protein 170A 2 2
MIRT627464 SYNRG synergin gamma 2 2
MIRT627913 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT636508 GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 2 2
MIRT636910 KIAA0408 KIAA0408 2 2
MIRT637302 ACTN2 actinin alpha 2 2 2
MIRT638230 SOGA3 SOGA family member 3 2 2
MIRT639880 STC1 stanniocalcin 1 2 2
MIRT639999 PHF21B PHD finger protein 21B 2 2
MIRT640149 CEP104 centrosomal protein 104 2 2
MIRT640699 SKI SKI proto-oncogene 2 2
MIRT640911 RAB13 RAB13, member RAS oncogene family 2 2
MIRT641518 CREBBP CREB binding protein 2 2
MIRT641990 OXSR1 oxidative stress responsive 1 2 2
MIRT642635 EPPIN epididymal peptidase inhibitor 2 2
MIRT642744 TDRD6 tudor domain containing 6 2 2
MIRT642759 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT642787 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 2 2
MIRT643054 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT643104 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT643316 TMEM151B transmembrane protein 151B 2 2
MIRT643715 ITK IL2 inducible T-cell kinase 2 2
MIRT644087 A4GALT alpha 1,4-galactosyltransferase (P blood group) 2 2
MIRT644112 SEL1L3 SEL1L family member 3 2 2
MIRT644377 ZNF286A zinc finger protein 286A 2 2
MIRT644408 FRMD6 FERM domain containing 6 2 2
MIRT644684 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT644744 CCDC174 coiled-coil domain containing 174 2 2
MIRT644876 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT645417 FAM110A family with sequence similarity 110 member A 2 2
MIRT645928 PLXNA3 plexin A3 2 2
MIRT646181 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT646554 TMCC2 transmembrane and coiled-coil domain family 2 2 2
MIRT647235 OR6A2 olfactory receptor family 6 subfamily A member 2 2 2
MIRT647263 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT647660 FOXL1 forkhead box L1 2 2
MIRT648284 TRAPPC2L trafficking protein particle complex 2 like 2 2
MIRT648493 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT648963 TMEM45B transmembrane protein 45B 2 2
MIRT649511 RAB17 RAB17, member RAS oncogene family 2 2
MIRT650446 CPXM2 carboxypeptidase X, M14 family member 2 2 2
MIRT650712 KRT32 keratin 32 2 2
MIRT651069 ZNF518B zinc finger protein 518B 2 4
MIRT651090 ZNF516 zinc finger protein 516 2 2
MIRT651193 ZNF281 zinc finger protein 281 2 2
MIRT651330 ZCCHC2 zinc finger CCHC-type containing 2 2 2
MIRT651445 XKR4 XK related 4 2 2
MIRT651517 WNT4 Wnt family member 4 2 4
MIRT651694 VPS13D vacuolar protein sorting 13 homolog D 2 2
MIRT652173 TRIM66 tripartite motif containing 66 2 2
MIRT652432 TMEM239 transmembrane protein 239 2 2
MIRT652656 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT652707 THBS2 thrombospondin 2 2 2
MIRT652812 TBL2 transducin beta like 2 2 2
MIRT653350 SMG7 SMG7, nonsense mediated mRNA decay factor 2 2
MIRT653471 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653658 SLC27A4 solute carrier family 27 member 4 2 2
MIRT654691 PSMB5 proteasome subunit beta 5 2 2
MIRT654735 PRLR prolactin receptor 2 2
MIRT654931 POLR3D RNA polymerase III subunit D 2 2
MIRT655209 PHAX phosphorylated adaptor for RNA export 2 2
MIRT655346 PCP4L1 Purkinje cell protein 4 like 1 2 2
MIRT655404 PANK1 pantothenate kinase 1 2 2
MIRT655482 PAK3 p21 (RAC1) activated kinase 3 2 2
MIRT655964 NDNF neuron derived neurotrophic factor 2 2
MIRT656017 MYPN myopalladin 2 2
MIRT656491 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT657151 ITGA1 integrin subunit alpha 1 2 2
MIRT657411 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT657608 GRID1 glutamate ionotropic receptor delta type subunit 1 2 2
MIRT658181 FBXO9 F-box protein 9 2 2
MIRT658932 DPY19L1 dpy-19 like C-mannosyltransferase 1 2 2
MIRT659028 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659092 DENR density regulated re-initiation and release factor 2 2
MIRT659204 CYBB cytochrome b-245 beta chain 2 2
MIRT659718 CCDC93 coiled-coil domain containing 93 2 2
MIRT660185 BNC2 basonuclin 2 2 2
MIRT660805 AIFM2 apoptosis inducing factor, mitochondria associated 2 2 2
MIRT660900 ADCY6 adenylate cyclase 6 2 2
MIRT660925 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT661741 DTHD1 death domain containing 1 2 2
MIRT661998 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT662639 PKHD1L1 PKHD1 like 1 2 2
MIRT664338 RAB8A RAB8A, member RAS oncogene family 2 2
MIRT666743 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT667070 PANK3 pantothenate kinase 3 2 2
MIRT667925 IGLON5 IgLON family member 5 2 2
MIRT668488 ETV3 ETS variant 3 2 2
MIRT668610 EHD4 EH domain containing 4 2 2
MIRT669419 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT669652 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT674005 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT680447 SLCO5A1 solute carrier organic anion transporter family member 5A1 2 2
MIRT684326 GTF3C4 general transcription factor IIIC subunit 4 2 2
MIRT685625 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT689978 ZNF185 zinc finger protein 185 with LIM domain 2 2
MIRT693962 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT698543 TFRC transferrin receptor 2 2
MIRT699982 RREB1 ras responsive element binding protein 1 2 2
MIRT702898 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT707383 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT708312 CDH8 cadherin 8 2 2
MIRT708406 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT709299 LDLRAD4 low density lipoprotein receptor class A domain containing 4 2 2
MIRT710326 STK40 serine/threonine kinase 40 2 2
MIRT710729 C19orf68 zinc finger SWIM-type containing 9 2 2
MIRT710970 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT711178 EMCN endomucin 2 2
MIRT711590 SETD1A SET domain containing 1A 2 2
MIRT711611 LHX5 LIM homeobox 5 2 2
MIRT711701 GMPR guanosine monophosphate reductase 2 2
MIRT711850 AMOTL2 angiomotin like 2 2 2
MIRT712358 NAT14 N-acetyltransferase 14 (putative) 2 2
MIRT712377 MTPN myotrophin 2 2
MIRT712469 KCNC3 potassium voltage-gated channel subfamily C member 3 2 2
MIRT712839 RHOA ras homolog family member A 2 2
MIRT713592 ANKMY1 ankyrin repeat and MYND domain containing 1 2 2
MIRT713982 ASIC4 acid sensing ion channel subunit family member 4 2 2
MIRT714534 ZBTB39 zinc finger and BTB domain containing 39 2 2
MIRT714570 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2 2
MIRT714610 EXO5 exonuclease 5 2 2
MIRT714943 ZNF330 zinc finger protein 330 2 2
MIRT715132 ACADL acyl-CoA dehydrogenase, long chain 2 2
MIRT716018 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT716204 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT716674 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT717366 EDN2 endothelin 2 2 2
MIRT718110 CRTC1 CREB regulated transcription coactivator 1 2 2
MIRT718502 GYS1 glycogen synthase 1 2 2
MIRT719146 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT719415 B4GALNT3 beta-1,4-N-acetyl-galactosaminyltransferase 3 2 2
MIRT719986 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT720347 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT720452 SLC16A5 solute carrier family 16 member 5 2 2
MIRT720493 TMEM178B transmembrane protein 178B 2 2
MIRT720666 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT721091 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT721334 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT721384 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT721508 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT721827 POU6F1 POU class 6 homeobox 1 2 2
MIRT722136 TTLL11 tubulin tyrosine ligase like 11 2 2
MIRT723070 GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 2 2
MIRT723115 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT723374 ZNF470 zinc finger protein 470 2 2
MIRT724446 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT724528 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT724643 PKDREJ polycystin family receptor for egg jelly 2 2
MIRT724711 CRAMP1L cramped chromatin regulator homolog 1 2 2
MIRT724750 ZNF391 zinc finger protein 391 2 2
MIRT724770 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6769b Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-6769b Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)
hsa-miR-6769b-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-6769b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-6769b-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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