miRTarBase - #MIRT716427


—
pre-miRNA Information
pre-miRNA hsa-mir-6132   
Genomic Coordinates chr7: 117020211 - 117020319
Description Homo sapiens miR-6132 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6132
Sequence 21| AGCAGGGCUGGGGAUUGCA |39
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1272646274 4 dbSNP
rs1211969145 8 dbSNP
rs1310278496 11 dbSNP
rs1044115534 13 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RAB15   
Synonyms -
Description RAB15, member RAS oncogene family
Transcript NM_198686   
Expression
Putative miRNA Targets on RAB15
3'UTR of RAB15
(miRNA target sites are highlighted)		 
>RAB15|NM_198686|3'UTR
   1 CAGAGCTGGTGCTGCAGGCCCATAGGAAGGAGCTGGAAGGCCTCCGGATGCGTGCCAGCAATGAGTTGGCACTGGCAGAG
  81 CTGGAGGAGGAGGAGGGCAAACCCGAGGGCCCAGCGAACTCTTCGAAAACCTGCTGGTGCTGAGTCCTGTGTGGGGCACC
 161 CCACACGACACCCCTCTTCCCTCAGGAGGCCCGTGGGCAGACAGGGGAGCCGGGGCTTTGCCCTGCTGCTGTCCTCTCGT
 241 GTGATGACCCTATTGAGTATCAGTAGCCACTACTCCCCCTGCCTGGCCCTGAGAGCGGCTCTGCTGTCATCTCAAGCAGC
 321 CCCTGTCCCCAGCCCGTCCACCCTGGAGTGGTCTTCTTCAGCCTGTTTCCCCAGCCACAGGCCTGCTACGACCCCCACGA
 401 TGTGCCGCAAGCACTGTCTCACCATCCCGCACCCACCAGACAACAGCCAGGGCTGGAGTCCAGGCCACTTTCAGCTGCTC
 481 CTTTCTCCGTGCATCGTGTCTCTTCTCTGCTTTTTCTCTCTTCCCCCACTTCTCTTTCTCTGACCCCTCCCCTCCGGTGC
 561 GTTTCGTATCAAAGCTCCTCAAACCCCGTCCCCCGTGTGTCCTGCTGTGTGCAGCTCGCTCTTTCCTTCCTTCCTAAGCT
 641 ATCCAAGGGGATGGACCCAGGCTCGTGGGGAGGTTCCACCCTTGGATCCAGGAAGAACCCTCCACCCTGCCTCGTGGGTG
 721 GGCCAAAGGCTACAGGGTGCTTCTTCCTCTTCCCCCACCCCCACTGTCCCTCATGTGCCATGGGCCTGCCTCCCCAGTGA
 801 CCTGCGAAAGTGGAGCATCGAGGTAGGAGGGAAACGGCAACCAGGGAGTCCTCGAGCCTGGGGCTGCCCTACCTCTACCC
 881 ATTCCCCGACCAGAGCTTTGCCCTTGCTTGGCTGCCCGCCTGCCTCTTTGGGGAACTGAGCTCAGAGGCAGGTGCTTCAG
 961 AGAAGGAAACAAAATGAGGGGTGGCAGGGATAAAAAGTCACCTCCATTCTCTACCTCCCATGCAGCATGAACACAATTTC
1041 TCTCCACCTGGCTCCCAAATTTAAAGATGTGGACCAAGGCCTGTGGGTACTCCAGGGGCAAGGAGAGCCCTGGGGTCAGT
1121 GACACTGTCAGGCCAACCATGCACTCCACAAAGGGGAGCATTTGGAAATGAAGGACTAGCTCCTATGTATCAGGTTAAGA
1201 GCAAGGGAGAGCTGGCCAGGGACAGCAGTTTGCACAGCAGAGGGGAATGTAGCAACAGCAGGGCCTCCTAGGCCCCATCT
1281 TCCATTTCTTAGGTAAGAAGAGCATTTCCTCAGACTCCCAGGCGGAGGACTGAGCCTAGCCTTCAGCAACCAAGGTTCTC
1361 CTGGGACCCAAAGTTTATGGGAGAAGGGCAAAGACTTCATGGGAAGAGAGAAGGAAGGCCCTGGGTAGAAACGCTTGGTG
1441 CTGTTCTCTTTGGCCTTTAAGACAAAGCGCTCATCTTGCCCTCTACCTCCTGATAGGCTTGAGGGTTTGCCAACCACACT
1521 GTGGCTACAGGTGGAGGGAAGAGGACTCCTTCCTCCAGAGTGCTATGTTCAGGAAGTTTCTTTAACCCCATATGGCCCAA
1601 GAGTAGCTCGTAGGAGGCCCTTTAAAGACGGAACAAGTAATTTACCAGTTCTACTGGGGTTCCTGCCCACCGTCCCAAGG
1681 TGGGCGAGGCCTAGGAAGAGGGTCATTCTTAAGCCACACATTAGCTGCACTGCGTGGCTGCAGCCAAAACAAAGAACTGG
1761 GTGTTGAGTATTCATCAACTAAGAACCAAAATCCAGGGCACTCATATGTGAAGGATAAGAACCTCACTTCCTTACTCCTC
1841 CAAAAAGAAGTGGGGAAAGAACCATCAAACCTTTCCTCCTGACTTACCAAACCAGGAAAACAGCAGGAGAGGGTGGCTCA
1921 GGACTTAGGGACAGGGTATAGCTTAGATGGTGGAAAGCAAAGGAGAGCAGGAAGTTGTAAATCACTGGCTAATGAGAAAA
2001 GGAGACAGCTAACTCTAGGATGAAGCTGTGACTAGGCTGGAGTTGCTTCCTTGAAGATGGGACTCCTTGGGTATCAAGAC
2081 CTATGCCACATCACACTGGGGCTAGGGAAGTAGGTGATGCCAGCCCTCAAGTCTGTCTTCAGCCAGGGACTTGAGAAGTT
2161 ATATTGGGCAGTGGCTCCAATCTGTGGACCAGTATTTCAGCTTTCCCTGAAGATCAGGCAGGGTGCCATTCATTGTCTTT
2241 CTCTCCTAGCCCCCTCAGGAAAGAAGGACTATATTTGTACTGTACCCTAGGGGTTCTGGAAGGGAAAACATGGAATCAGG
2321 ATTCTATAGACTGATAGGCCCTATCCACAAGGGCCATGACTGGGAAAAGGTATGGGAGCAGAAGGAGAATTGGGATTTTA
2401 GGGTGCAGCTACGCTCACCCTAAACTTTTGGTGGCCTGGGGCATGTCTTGAGGCCCAGACTGTTAACCAGGCTCTGCTGG
2481 CCTGTTTACTCGTCACCACCTCTGCACCTGCTGTCTTGAGACTCCATCCAGCCCCAGGCACGCCACCTGCTCCTGAGCCT
2561 CCACTATCTCCCTGTGACGGGTGAACTTCGTGTACTGTGTCTCGGGTCCATATATGAATTGTGAGCAGGGTTCATCTATT
2641 TTAAACACAGATGTTTACAAAATAAAGATTATTTCAAACCACCAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acGUUAGGGGUCGGGACGa 5'
            |::  |:: ||||||| 
Target 5' gcCGGGGCTTTGCCCTGCt 3'
 209 - 227 145.00 -17.80
2 
miRNA  3' acGUUAGGGG----UCGGGACGa 5'
            | :|||||     |:||||| 
Target 5' ccCCGTCCCCCGTGTGTCCTGCt 3'
 584 - 606 135.00 -21.70
3 
miRNA  3' acguuAGGGGUCGGGACga 5'
               | ||::||||||  
Target 5' cccccTGCCTGGCCCTGag 3'
 275 - 293 134.00 -18.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM8481159 7 COSMIC
COSM3497197 10 COSMIC
COSM9025810 14 COSMIC
COSM8463700 19 COSMIC
COSM8402622 42 COSMIC
COSM6761270 46 COSMIC
COSM7220857 55 COSMIC
COSM6761278 95 COSMIC
COSM8277545 98 COSMIC
COSM1587537 116 COSMIC
COSM5422034 142 COSMIC
COSN22163193 246 COSMIC
COSN1170076 422 COSMIC
COSN30161350 798 COSMIC
COSN28710888 836 COSMIC
COSN19662385 843 COSMIC
COSN31595418 1056 COSMIC
COSN31583823 1095 COSMIC
COSN5389004 1129 COSMIC
COSN31480125 1428 COSMIC
COSN26565725 1570 COSMIC
COSN31607472 1580 COSMIC
COSN31549316 1601 COSMIC
COSN31540122 1700 COSMIC
COSN19657866 2442 COSMIC
COSN31485490 2459 COSMIC
COSN6542719 2496 COSMIC
COSN26678123 2532 COSMIC
COSN1657152 2602 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs755765495 1 dbSNP
rs1374705899 3 dbSNP
rs778349231 4 dbSNP
rs1317213184 6 dbSNP
rs1400423252 7 dbSNP
rs754389307 9 dbSNP
rs1167668991 14 dbSNP
rs1460442865 16 dbSNP
rs370909235 23 dbSNP
rs1417216378 25 dbSNP
rs1166808617 33 dbSNP
rs779573746 34 dbSNP
rs1294426993 35 dbSNP
rs1375582808 39 dbSNP
rs1416181776 41 dbSNP
rs1476506466 43 dbSNP
rs1240520813 45 dbSNP
rs530144601 46 dbSNP
rs750200493 51 dbSNP
rs761598155 52 dbSNP
rs753714682 53 dbSNP
rs764146525 55 dbSNP
rs947797436 58 dbSNP
rs760663241 60 dbSNP
rs1045444691 63 dbSNP
rs775678613 65 dbSNP
rs916242151 67 dbSNP
rs983828410 68 dbSNP
rs1359258315 72 dbSNP
rs1269185738 80 dbSNP
rs1436776374 82 dbSNP
rs1186861020 84 dbSNP
rs772162699 90 dbSNP
rs759780594 95 dbSNP
rs750167619 97 dbSNP
rs758236094 97 dbSNP
rs774743235 98 dbSNP
rs771356575 100 dbSNP
rs1172029311 102 dbSNP
rs749937244 104 dbSNP
rs187980551 105 dbSNP
rs1167509539 106 dbSNP
rs1478509131 109 dbSNP
rs1254641074 112 dbSNP
rs770399526 113 dbSNP
rs746474278 115 dbSNP
rs779668016 116 dbSNP
rs1019869970 119 dbSNP
rs1206576447 121 dbSNP
rs113600456 122 dbSNP
rs757929489 124 dbSNP
rs780746243 125 dbSNP
rs1219416988 128 dbSNP
rs1304811316 130 dbSNP
rs1028989832 131 dbSNP
rs778548277 135 dbSNP
rs757028315 144 dbSNP
rs925464525 146 dbSNP
rs753730535 147 dbSNP
rs763907028 149 dbSNP
rs561192010 151 dbSNP
rs1445022122 153 dbSNP
rs557499398 156 dbSNP
rs1328346520 157 dbSNP
rs1415239695 159 dbSNP
rs1397052845 160 dbSNP
rs1218288201 163 dbSNP
rs945633181 163 dbSNP
rs767593392 164 dbSNP
rs1262212843 165 dbSNP
rs759695376 166 dbSNP
rs376409999 167 dbSNP
rs1479639698 170 dbSNP
rs370219889 171 dbSNP
rs555279578 174 dbSNP
rs1275352545 190 dbSNP
rs773670694 191 dbSNP
rs1277669166 192 dbSNP
rs770184172 193 dbSNP
rs1309076936 194 dbSNP
rs906661575 195 dbSNP
rs1364295460 200 dbSNP
rs1047008861 202 dbSNP
rs1419289356 207 dbSNP
rs1160851651 210 dbSNP
rs535385566 211 dbSNP
rs947828343 212 dbSNP
rs1453530427 213 dbSNP
rs955356318 215 dbSNP
rs1171291019 226 dbSNP
rs534468553 234 dbSNP
rs1397289451 236 dbSNP
rs1028866113 238 dbSNP
rs11540871 239 dbSNP
rs757450067 241 dbSNP
rs1374165396 244 dbSNP
rs1225613957 252 dbSNP
rs765850176 256 dbSNP
rs1305174352 259 dbSNP
rs963085329 260 dbSNP
rs930938283 262 dbSNP
rs1016771367 277 dbSNP
rs1273624023 280 dbSNP
rs1469761436 281 dbSNP
rs1156978781 287 dbSNP
rs572625593 296 dbSNP
rs1004026477 297 dbSNP
rs1178532642 313 dbSNP
rs1472425231 325 dbSNP
rs1166102092 327 dbSNP
rs1420552676 328 dbSNP
rs887039551 329 dbSNP
rs552609490 335 dbSNP
rs1489831764 336 dbSNP
rs965683919 349 dbSNP
rs1444490741 358 dbSNP
rs1013950943 362 dbSNP
rs1296577231 369 dbSNP
rs1222251240 373 dbSNP
rs1415695227 380 dbSNP
rs1293662298 382 dbSNP
rs1336683879 384 dbSNP
rs183439502 389 dbSNP
rs1423705020 390 dbSNP
rs570067195 399 dbSNP
rs73281761 406 dbSNP
rs904231437 407 dbSNP
rs1482517313 412 dbSNP
rs1188234642 422 dbSNP
rs777190040 428 dbSNP
rs1043918415 429 dbSNP
rs1010957139 430 dbSNP
rs530599427 440 dbSNP
rs1412167674 441 dbSNP
rs945518599 449 dbSNP
rs191126978 452 dbSNP
rs113708067 456 dbSNP
rs1315012252 457 dbSNP
rs1351684001 462 dbSNP
rs1316388322 468 dbSNP
rs11540872 477 dbSNP
rs556848608 479 dbSNP
rs536608978 484 dbSNP
rs137942279 485 dbSNP
rs545413948 488 dbSNP
rs1017407205 489 dbSNP
rs1282053793 495 dbSNP
rs1048150586 496 dbSNP
rs982643736 500 dbSNP
rs1191697184 503 dbSNP
rs1187247128 509 dbSNP
rs1243122177 509 dbSNP
rs1476665381 511 dbSNP
rs1418803381 522 dbSNP
rs931055443 522 dbSNP
rs918223636 524 dbSNP
rs951178590 527 dbSNP
rs867443729 528 dbSNP
rs1024264881 532 dbSNP
rs1269572098 536 dbSNP
rs1014170723 543 dbSNP
rs576835956 544 dbSNP
rs1034020752 548 dbSNP
rs1345581521 553 dbSNP
rs11540873 556 dbSNP
rs1363772023 558 dbSNP
rs1234359731 559 dbSNP
rs914424305 560 dbSNP
rs904284634 561 dbSNP
rs572148407 563 dbSNP
rs1199577899 565 dbSNP
rs868399954 566 dbSNP
rs1285317971 567 dbSNP
rs1449097399 568 dbSNP
rs1214223485 570 dbSNP
rs774957574 574 dbSNP
rs1455121404 585 dbSNP
rs1301098790 587 dbSNP
rs1393413039 588 dbSNP
rs1477789598 593 dbSNP
rs1220303985 594 dbSNP
rs1009730570 595 dbSNP
rs958122290 595 dbSNP
rs1316024246 609 dbSNP
rs1387782434 612 dbSNP
rs892628213 617 dbSNP
rs1051172319 618 dbSNP
rs934247773 624 dbSNP
rs1368164028 625 dbSNP
rs1231983423 626 dbSNP
rs970991868 648 dbSNP
rs1025619507 651 dbSNP
rs1222401006 654 dbSNP
rs1322745066 656 dbSNP
rs1469300047 658 dbSNP
rs1468493107 659 dbSNP
rs1251149086 664 dbSNP
rs1012519891 665 dbSNP
rs1176581228 671 dbSNP
rs921493471 673 dbSNP
rs543532551 677 dbSNP
rs941347828 680 dbSNP
rs909993550 691 dbSNP
rs982864290 695 dbSNP
rs1449480988 703 dbSNP
rs995249508 706 dbSNP
rs1181366112 713 dbSNP
rs1167010184 714 dbSNP
rs534418601 730 dbSNP
rs1482757400 752 dbSNP
rs1255750521 754 dbSNP
rs1211312781 756 dbSNP
rs951229497 761 dbSNP
rs917097455 762 dbSNP
rs574930994 774 dbSNP
rs1288056443 781 dbSNP
rs958669434 782 dbSNP
rs1034652418 789 dbSNP
rs999894481 797 dbSNP
rs555240911 802 dbSNP
rs968771114 805 dbSNP
rs1020025313 806 dbSNP
rs1009948969 810 dbSNP
rs57586732 811 dbSNP
rs1252836945 813 dbSNP
rs932587111 819 dbSNP
rs118115391 820 dbSNP
rs1250710382 823 dbSNP
rs1378769046 827 dbSNP
rs558958388 829 dbSNP
rs998730392 831 dbSNP
rs1475428459 834 dbSNP
rs900108929 835 dbSNP
rs2296325 836 dbSNP
rs1467342516 837 dbSNP
rs936740283 842 dbSNP
rs2296326 843 dbSNP
rs1427349714 847 dbSNP
rs978215564 850 dbSNP
rs909878712 853 dbSNP
rs769395554 854 dbSNP
rs1340397960 856 dbSNP
rs1161186215 859 dbSNP
rs1228867563 864 dbSNP
rs1253089328 866 dbSNP
rs769292240 874 dbSNP
rs917316630 884 dbSNP
rs755083713 887 dbSNP
rs992674913 888 dbSNP
rs1486804566 893 dbSNP
rs1189761786 897 dbSNP
rs1183262760 916 dbSNP
rs958771898 917 dbSNP
rs927256291 918 dbSNP
rs550005839 919 dbSNP
rs1374256890 922 dbSNP
rs371544445 930 dbSNP
rs60532751 930 dbSNP
rs532367178 932 dbSNP
rs1167470483 937 dbSNP
rs995696921 945 dbSNP
rs979078291 978 dbSNP
rs530257288 980 dbSNP
rs1383199882 983 dbSNP
rs745517064 984 dbSNP
rs1343553892 987 dbSNP
rs1276822077 989 dbSNP
rs1242643031 992 dbSNP
rs1321217862 997 dbSNP
rs932562802 1006 dbSNP
rs988411287 1013 dbSNP
rs954473789 1018 dbSNP
rs780578222 1032 dbSNP
rs1263736041 1036 dbSNP
rs1447627962 1042 dbSNP
rs1398010393 1054 dbSNP
rs1348390679 1067 dbSNP
rs1395225735 1070 dbSNP
rs868535892 1071 dbSNP
rs781171714 1079 dbSNP
rs893094070 1082 dbSNP
rs1173527287 1088 dbSNP
rs1377382660 1098 dbSNP
rs998385997 1108 dbSNP
rs1454649520 1109 dbSNP
rs1291045529 1113 dbSNP
rs150710253 1117 dbSNP
rs1435095679 1123 dbSNP
rs934466339 1126 dbSNP
rs1410336866 1144 dbSNP
rs1326643908 1146 dbSNP
rs1373302693 1147 dbSNP
rs1372377228 1158 dbSNP
rs1161425666 1161 dbSNP
rs1300876178 1168 dbSNP
rs758525584 1197 dbSNP
rs1018565163 1200 dbSNP
rs1239464849 1203 dbSNP
rs1456927499 1204 dbSNP
rs1368555952 1207 dbSNP
rs1166393935 1217 dbSNP
rs1208047246 1227 dbSNP
rs1416994572 1228 dbSNP
rs1469441143 1232 dbSNP
rs1189048030 1241 dbSNP
rs1266198865 1249 dbSNP
rs924466860 1250 dbSNP
rs978543246 1256 dbSNP
rs1006226814 1262 dbSNP
rs1457122024 1263 dbSNP
rs754755245 1264 dbSNP
rs888664429 1268 dbSNP
rs1396727787 1273 dbSNP
rs1410179591 1276 dbSNP
rs1434374593 1279 dbSNP
rs1293058176 1288 dbSNP
rs949506454 1291 dbSNP
rs555583077 1293 dbSNP
rs1374323615 1315 dbSNP
rs1181956610 1319 dbSNP
rs1289926244 1320 dbSNP
rs1326825188 1320 dbSNP
rs1323476082 1321 dbSNP
rs756718170 1321 dbSNP
rs45603938 1323 dbSNP
rs528338892 1324 dbSNP
rs141216198 1330 dbSNP
rs1480746850 1333 dbSNP
rs1178587008 1335 dbSNP
rs959595126 1341 dbSNP
rs777740133 1347 dbSNP
rs974332872 1350 dbSNP
rs1404165970 1354 dbSNP
rs937229651 1355 dbSNP
rs1308319004 1365 dbSNP
rs375164585 1378 dbSNP
rs961513564 1381 dbSNP
rs1015763910 1397 dbSNP
rs1408964846 1398 dbSNP
rs552084086 1415 dbSNP
rs890911233 1416 dbSNP
rs947309212 1423 dbSNP
rs11540874 1428 dbSNP
rs913120883 1432 dbSNP
rs1386149575 1433 dbSNP
rs1390825653 1435 dbSNP
rs1294822232 1438 dbSNP
rs996498510 1467 dbSNP
rs1455285223 1468 dbSNP
rs988463855 1469 dbSNP
rs879250310 1473 dbSNP
rs1054278745 1481 dbSNP
rs1387401617 1489 dbSNP
rs1159469589 1495 dbSNP
rs1239639821 1515 dbSNP
rs1472064636 1516 dbSNP
rs758305439 1519 dbSNP
rs1181797927 1532 dbSNP
rs1420273203 1546 dbSNP
rs1430407544 1561 dbSNP
rs954358468 1563 dbSNP
rs1370148727 1565 dbSNP
rs766831492 1566 dbSNP
rs1414657968 1571 dbSNP
rs1313246651 1573 dbSNP
rs1030075513 1577 dbSNP
rs531990338 1579 dbSNP
rs974888334 1580 dbSNP
rs1283558322 1586 dbSNP
rs964461037 1591 dbSNP
rs563341428 1593 dbSNP
rs185987609 1595 dbSNP
rs1268120163 1598 dbSNP
rs1229934866 1601 dbSNP
rs1431356042 1607 dbSNP
rs3759681 1609 dbSNP
rs1025890169 1610 dbSNP
rs1441083521 1615 dbSNP
rs1209974641 1626 dbSNP
rs994194162 1629 dbSNP
rs1466668235 1630 dbSNP
rs895818249 1630 dbSNP
rs1057098157 1641 dbSNP
rs765069232 1647 dbSNP
rs1330869095 1667 dbSNP
rs561441117 1671 dbSNP
rs72625649 1672 dbSNP
rs1175761554 1674 dbSNP
rs535568669 1675 dbSNP
rs1331645541 1679 dbSNP
rs572712106 1682 dbSNP
rs559154860 1683 dbSNP
rs182790991 1685 dbSNP
rs1363845629 1686 dbSNP
rs1298764587 1703 dbSNP
rs1320728454 1713 dbSNP
rs1458548605 1715 dbSNP
rs947208285 1719 dbSNP
rs1317890553 1720 dbSNP
rs1363840361 1721 dbSNP
rs919941926 1722 dbSNP
rs913173110 1726 dbSNP
rs1387574992 1730 dbSNP
rs1342506269 1733 dbSNP
rs375853849 1734 dbSNP
rs933019695 1742 dbSNP
rs1285469751 1744 dbSNP
rs530015896 1751 dbSNP
rs1331820085 1754 dbSNP
rs922939394 1755 dbSNP
rs1207402345 1757 dbSNP
rs1247421958 1760 dbSNP
rs908694533 1764 dbSNP
rs987026181 1765 dbSNP
rs955280660 1766 dbSNP
rs1245170646 1770 dbSNP
rs1477861495 1775 dbSNP
rs1028044167 1778 dbSNP
rs1465952801 1801 dbSNP
rs1458689768 1804 dbSNP
rs1156898879 1808 dbSNP
rs1378679281 1813 dbSNP
rs996570790 1815 dbSNP
rs1387219103 1822 dbSNP
rs138554413 1834 dbSNP
rs1324995481 1842 dbSNP
rs1032648262 1850 dbSNP
rs1435382543 1852 dbSNP
rs1280442745 1860 dbSNP
rs1352717506 1864 dbSNP
rs1268077437 1868 dbSNP
rs1447675849 1868 dbSNP
rs1336172667 1870 dbSNP
rs1211712133 1871 dbSNP
rs998722547 1873 dbSNP
rs561271252 1875 dbSNP
rs964837923 1893 dbSNP
rs1182806869 1895 dbSNP
rs1045958968 1901 dbSNP
rs1473464867 1907 dbSNP
rs908934371 1909 dbSNP
rs1411113502 1932 dbSNP
rs1466467433 1941 dbSNP
rs3759682 1948 dbSNP
rs1387963822 1949 dbSNP
rs750657124 1959 dbSNP
rs556533423 1967 dbSNP
rs1308290924 1980 dbSNP
rs952838530 1982 dbSNP
rs1352663120 1983 dbSNP
rs1408363101 1987 dbSNP
rs1288191192 1993 dbSNP
rs1025941144 1994 dbSNP
rs1247645406 2000 dbSNP
rs1282435907 2008 dbSNP
rs1345477395 2013 dbSNP
rs1196557824 2015 dbSNP
rs1257628510 2017 dbSNP
rs1277014908 2018 dbSNP
rs994413649 2021 dbSNP
rs960239262 2023 dbSNP
rs1036119167 2045 dbSNP
rs1001513221 2046 dbSNP
rs1202750436 2060 dbSNP
rs938078420 2062 dbSNP
rs1424261541 2071 dbSNP
rs1226090138 2079 dbSNP
rs905970287 2081 dbSNP
rs536304590 2086 dbSNP
rs1472190583 2087 dbSNP
rs1043127001 2089 dbSNP
rs1427488918 2090 dbSNP
rs1038413310 2091 dbSNP
rs940263847 2092 dbSNP
rs1398265844 2098 dbSNP
rs1332800063 2099 dbSNP
rs1436800648 2100 dbSNP
rs1340455542 2104 dbSNP
rs1228211687 2105 dbSNP
rs1300003602 2109 dbSNP
rs1011401846 2110 dbSNP
rs1338377830 2111 dbSNP
rs1340280097 2128 dbSNP
rs908817917 2130 dbSNP
rs1333133143 2135 dbSNP
rs1273561000 2138 dbSNP
rs541498006 2148 dbSNP
rs1403375613 2162 dbSNP
rs987472530 2165 dbSNP
rs1253969030 2171 dbSNP
rs367809164 2187 dbSNP
rs1391496560 2194 dbSNP
rs767736010 2197 dbSNP
rs921436158 2215 dbSNP
rs567441312 2216 dbSNP
rs891620564 2218 dbSNP
rs761934800 2221 dbSNP
rs1378526343 2222 dbSNP
rs1389621591 2224 dbSNP
rs1467883290 2225 dbSNP
rs1301503952 2229 dbSNP
rs1169364787 2232 dbSNP
rs957154188 2234 dbSNP
rs1322566685 2240 dbSNP
rs547944766 2249 dbSNP
rs1363119055 2255 dbSNP
rs933244093 2260 dbSNP
rs1187121480 2267 dbSNP
rs998503261 2269 dbSNP
rs774550744 2277 dbSNP
rs1235102344 2280 dbSNP
rs1254094882 2282 dbSNP
rs764734464 2285 dbSNP
rs1039125119 2296 dbSNP
rs1209282912 2298 dbSNP
rs1249303987 2305 dbSNP
rs1463179939 2310 dbSNP
rs943038990 2317 dbSNP
rs1267579237 2325 dbSNP
rs1434616032 2326 dbSNP
rs1202920954 2327 dbSNP
rs1174386475 2338 dbSNP
rs1341428604 2345 dbSNP
rs1377433710 2348 dbSNP
rs1458163731 2351 dbSNP
rs1162037013 2360 dbSNP
rs1386478478 2362 dbSNP
rs1014603070 2366 dbSNP
rs1229923104 2369 dbSNP
rs908981113 2370 dbSNP
rs879491160 2372 dbSNP
rs1385324182 2376 dbSNP
rs1245076915 2378 dbSNP
rs1344672077 2382 dbSNP
rs1002280104 2385 dbSNP
rs1228882723 2385 dbSNP
rs534491950 2388 dbSNP
rs565566266 2390 dbSNP
rs190962880 2402 dbSNP
rs532477178 2405 dbSNP
rs1489221637 2406 dbSNP
rs1189100996 2409 dbSNP
rs887126110 2412 dbSNP
rs370061770 2413 dbSNP
rs1435940022 2414 dbSNP
rs549771176 2425 dbSNP
rs1184845109 2429 dbSNP
rs960291030 2432 dbSNP
rs1035931708 2434 dbSNP
rs934245815 2435 dbSNP
rs921425923 2441 dbSNP
rs10121 2442 dbSNP
rs970079647 2443 dbSNP
rs545603099 2444 dbSNP
rs1371457992 2455 dbSNP
rs541155663 2460 dbSNP
rs1011622703 2462 dbSNP
rs3087955 2467 dbSNP
rs1045712 2472 dbSNP
rs1052904390 2480 dbSNP
rs1348547058 2482 dbSNP
rs1223164335 2484 dbSNP
rs565522127 2491 dbSNP
rs997277701 2492 dbSNP
rs770135776 2496 dbSNP
rs1179798001 2498 dbSNP
rs8006570 2505 dbSNP
rs576678863 2511 dbSNP
rs556254194 2512 dbSNP
rs1472512452 2513 dbSNP
rs1048725688 2516 dbSNP
rs144787664 2517 dbSNP
rs1415989123 2520 dbSNP
rs1422108083 2526 dbSNP
rs370200361 2527 dbSNP
rs1391010415 2531 dbSNP
rs972924635 2537 dbSNP
rs1431921778 2539 dbSNP
rs938844699 2541 dbSNP
rs994695117 2542 dbSNP
rs1177226987 2552 dbSNP
rs1295472883 2555 dbSNP
rs928919097 2559 dbSNP
rs770551805 2563 dbSNP
rs1303384062 2564 dbSNP
rs1381315744 2574 dbSNP
rs898568385 2578 dbSNP
rs970678696 2579 dbSNP
rs1230179097 2581 dbSNP
rs1272880380 2582 dbSNP
rs1021582063 2589 dbSNP
rs573728897 2590 dbSNP
rs1348187936 2595 dbSNP
rs111598126 2599 dbSNP
rs138842271 2601 dbSNP
rs1183046158 2603 dbSNP
rs180857782 2604 dbSNP
rs189644578 2614 dbSNP
rs901675516 2615 dbSNP
rs370023087 2617 dbSNP
rs936145530 2623 dbSNP
rs185920751 2629 dbSNP
rs59865464 2635 dbSNP
rs1412443055 2636 dbSNP
rs1445810222 2638 dbSNP
rs1335423156 2639 dbSNP
rs1365299819 2646 dbSNP
rs569950409 2654 dbSNP
rs926139662 2659 dbSNP
rs977157041 2663 dbSNP
rs1245605856 2674 dbSNP
rs1007483746 2678 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124B_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + B ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acGUUAGGGGUCGGGACGa 5'
            |::  |:: ||||||| 
Target 5' --CGGGGCUUUGCCCUGC- 3'
 		1 - 16
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_124B_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + B
Location of target site ENST00000436278.2 | 3UTR | CGGGGCUUUGCCCUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
82 hsa-miR-6132 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT067294 NECAP1 NECAP endocytosis associated 1 2 10
MIRT100110 ABT1 activator of basal transcription 1 2 8
MIRT358583 CANX calnexin 2 2
MIRT445247 SEMA5A semaphorin 5A 2 2
MIRT445764 CCND3 cyclin D3 2 2
MIRT452388 LY6E lymphocyte antigen 6 family member E 2 4
MIRT452829 FAM131B family with sequence similarity 131 member B 2 2
MIRT453450 GLG1 golgi glycoprotein 1 2 2
MIRT455435 ID3 inhibitor of DNA binding 3, HLH protein 2 2
MIRT460629 IGFBP4 insulin like growth factor binding protein 4 2 2
MIRT461607 DPH2 DPH2 homolog 2 2
MIRT461989 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT464258 VCL vinculin 2 2
MIRT465713 TNFAIP1 TNF alpha induced protein 1 2 2
MIRT466475 TECPR2 tectonin beta-propeller repeat containing 2 2 7
MIRT467119 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 4
MIRT468299 SFT2D2 SFT2 domain containing 2 2 2
MIRT469696 RAB5B RAB5B, member RAS oncogene family 2 8
MIRT469904 PTRF caveolae associated protein 1 2 2
MIRT470015 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT471385 PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2 2
MIRT471409 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT471719 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT473608 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT476328 GLTSCR1L BRD4 interacting chromatin remodeling complex associated protein like 2 2
MIRT479448 CDK6 cyclin dependent kinase 6 2 2
MIRT482032 AMER1 APC membrane recruitment protein 1 2 2
MIRT482360 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT484661 HOXD3 homeobox D3 2 4
MIRT486828 NDOR1 NADPH dependent diflavin oxidoreductase 1 2 2
MIRT487069 CLASP1 cytoplasmic linker associated protein 1 2 4
MIRT487196 NFASC neurofascin 2 4
MIRT487448 TFAP2B transcription factor AP-2 beta 2 4
MIRT487517 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT487640 BRSK2 BR serine/threonine kinase 2 2 4
MIRT487755 SKI SKI proto-oncogene 2 4
MIRT489944 CPLX1 complexin 1 2 2
MIRT491101 MSI1 musashi RNA binding protein 1 2 4
MIRT491181 LAMA5 laminin subunit alpha 5 2 2
MIRT492355 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT493918 FAM127B retrotransposon Gag like 8A 2 4
MIRT493932 FAM127A retrotransposon Gag like 8C 2 4
MIRT494679 ARID3A AT-rich interaction domain 3A 2 2
MIRT494814 AKAP11 A-kinase anchoring protein 11 2 2
MIRT494835 ADCY9 adenylate cyclase 9 2 2
MIRT495455 PNMAL2 paraneoplastic Ma antigen family member 8B 2 2
MIRT496962 MAP1LC3B microtubule associated protein 1 light chain 3 beta 2 2
MIRT526228 MTRNR2L5 MT-RNR2-like 5 2 2
MIRT531028 TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3 2 2
MIRT557110 HOXA3 homeobox A3 2 2
MIRT560514 POGK pogo transposable element derived with KRAB domain 2 2
MIRT567753 DLC1 DLC1 Rho GTPase activating protein 2 2
MIRT569608 TRIM29 tripartite motif containing 29 2 2
MIRT570242 CPNE5 copine 5 2 2
MIRT572327 HSPB6 heat shock protein family B (small) member 6 2 2
MIRT572373 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT575024 Tecpr2 tectonin beta-propeller repeat containing 2 2 5
MIRT576146 Hmox1 heme oxygenase 1 2 2
MIRT612443 SMOC2 SPARC related modular calcium binding 2 2 2
MIRT615404 VDAC2 voltage dependent anion channel 2 2 2
MIRT629114 CYCS cytochrome c, somatic 2 2
MIRT631362 FOXI2 forkhead box I2 2 2
MIRT639322 THBD thrombomodulin 2 2
MIRT643797 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT669687 ABLIM1 actin binding LIM protein 1 2 2
MIRT670595 LLGL1 LLGL1, scribble cell polarity complex component 2 4
MIRT691190 NIF3L1 NGG1 interacting factor 3 like 1 2 2
MIRT691688 FLOT2 flotillin 2 2 2
MIRT697127 OTUD5 OTU deubiquitinase 5 2 2
MIRT700814 PHLDA2 pleckstrin homology like domain family A member 2 2 2
MIRT701248 NUP35 nucleoporin 35 2 2
MIRT702362 KLHL15 kelch like family member 15 2 2
MIRT703325 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT706060 PKD1 polycystin 1, transient receptor potential channel interacting 2 2
MIRT710475 CDH5 cadherin 5 2 2
MIRT713018 SLC4A2 solute carrier family 4 member 2 2 2
MIRT716427 RAB15 RAB15, member RAS oncogene family 2 2
MIRT718093 ABHD12 abhydrolase domain containing 12 2 2
MIRT718542 PIGQ phosphatidylinositol glycan anchor biosynthesis class Q 2 2
MIRT719122 CACFD1 calcium channel flower domain containing 1 2 2
MIRT721393 LDLRAD4 low density lipoprotein receptor class A domain containing 4 2 2
MIRT736283 CDC42 cell division cycle 42 2 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6132 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-6132 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-6132 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-6132 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-6132 Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-6132 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-6132 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-6132 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-6132 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)

Error report submission