miRTarBase - #MIRT720671


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pre-miRNA Information
pre-miRNA hsa-mir-2355   
Genomic Coordinates chr2: 207109987 - 207110073
Description Homo sapiens miR-2355 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-2355-5p
Sequence 11| AUCCCCAGAUACAAUGGACAA |31
Evidence Experimental
Experiments SOLiD
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 1 2 - 207110063 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1268296297 4 dbSNP
rs1361046879 5 dbSNP
rs1219551997 6 dbSNP
rs1295756820 12 dbSNP
rs1345273529 15 dbSNP
rs977145706 15 dbSNP
rs1209629984 20 dbSNP
rs759940260 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC39A13   
Synonyms LZT-Hs9
Description solute carrier family 39 member 13
Transcript NM_001128225   
Other Transcripts NM_152264   
Expression
Putative miRNA Targets on SLC39A13
3'UTR of SLC39A13
(miRNA target sites are highlighted)		 
>SLC39A13|NM_001128225|3'UTR
   1 CTTTCCCTGATGCCGACGCCCCTGCCCCCTGCAGCAATAAGATGCTCGGATTCACTCTGTGACCGCATATGTGAGAGGCA
  81 GAGAGGGCGAGTGGCTGCGAGAGAGAATGAGCCTCCCGCCAGACAGGAGGGAGGTGCGTGTGGATGTATGTGGTGTGCAC
 161 ATGTGGCCAGAGGTGTGTGCGCGAGACCGACACTGTGATCCCTGTGCTGGGTCCGGGGCCCAGTGTAGCGCCTGTCCCCA
 241 GCCATGCTGTGGTTACCTCTCCTTGCCGCCCTGTCACCTTCACCTCCCGGAGTAAGCAGCGAGGAAGAGCAGCACTGGTC
 321 CCAAGCAGAGGCCTTGCCCTGCTGGGACCCCGGGAGTGAGAGCAGCCCAAGGATCCAGGGTGCAGGGAACTCCAGAGCTG
 401 CCCACCTCCCACTGCCCCCTCAGCACACACACAGTCCCCAGGCGGCCTAGGGGCCAAGGCTGGGGCGGCTTTGGTCCCTT
 481 TTCCTGGCCCTTCCTTCCCCACTTCTAAGCCAAAGAAAGGAGAGGCAGGTGCTCCTGTACCCCAGCCCCACTCAGCACTG
 561 ACAGTCCCCAGCTCCTAGTAGTGAGCTGGGAGGCGCTTCCTAAGACCCTTTCCTCAGGGCTGCCCTGGGAGCTCATTCCT
 641 GGCCAACACGCCCTGGCAGCACCAGCAGCTCTTGCCACCTCCAGCTGCCAAACAGCAGCCTGCCGGGCAGGGAGCAGCCC
 721 CAGGCCAGAGAGGCCTCCCGGTCCAGCTCAGGGATGCTCCTGCCAGCACAGGGGCCAGGGACTCCTGGAGCAGGCACATA
 801 GTGAGCCCGGGCAGCCCTGCCCAGCTCAGGCCCCTTTCCTTCCCCATTGAGGTTGGGGTAGGTGGGGGCGGTGAGGGCTC
 881 CACGTTGTCAGCGCTCAGGAATGTGCTCCGGCAGAGTGCTGAAGCCATAATCCCCAACCATTTCCCTTGGCTGACGCCCA
 961 GGTACTCAGCTGGCCCACTCCACAGCCAGGCCTGGCCCTGCCCTTCACCGTGGATGTTTTCAGAAGTGGCCATCGAGAGG
1041 TCTGGATGGTTTTATAGCAACTTTGCTGTGATTCCGTTTGTATCTGTAAATATTTGTTCTATAGATAAGATACAAATAAA
1121 TATTATCCACATACTGG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aacaGGUAACAUAGACCCCua 5'
              |||||| : :|||||  
Target 5' ttccCCATTGAGGTTGGGGta 3'
 840 - 860 129.00 -18.10
2 
miRNA  3' aaCAGGUAACAUAGACCCCua 5'
            | |||  |   ||||||  
Target 5' ggGGCCAAGG---CTGGGGcg 3'
 450 - 467 124.00 -13.40
3 
miRNA  3' aacAGGUAACAUAGACCCcua 5'
             |||  |||: |||||   
Target 5' tgaTCC-CTGTG-CTGGGtcc 3'
 196 - 214 112.00 -11.12
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
389990 20 ClinVar
1203993 120 ClinVar
COSN24386743 10 COSMIC
COSN31561925 15 COSMIC
COSN31581163 30 COSMIC
COSN31560489 39 COSMIC
COSN19734170 49 COSMIC
COSN30464583 64 COSMIC
COSN30450124 65 COSMIC
COSN30464598 65 COSMIC
COSN30678431 89 COSMIC
COSN31555276 119 COSMIC
COSN18736177 120 COSMIC
COSN31481485 138 COSMIC
COSN30111180 162 COSMIC
COSN24390020 180 COSMIC
COSN31591451 202 COSMIC
COSN31541506 203 COSMIC
COSN31548399 252 COSMIC
COSN6609959 289 COSMIC
COSN5912742 313 COSMIC
COSN20108210 377 COSMIC
COSN8280502 470 COSMIC
COSN6609960 490 COSMIC
COSN31541913 650 COSMIC
COSN31485297 761 COSMIC
COSN30175926 831 COSMIC
COSN31489640 870 COSMIC
COSN32056477 1099 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs762617893 1 dbSNP
rs1337753031 5 dbSNP
rs765810381 7 dbSNP
rs773852837 11 dbSNP
rs759101960 12 dbSNP
rs767627761 15 dbSNP
rs372474851 16 dbSNP
rs556077570 18 dbSNP
rs763897852 19 dbSNP
rs750637189 20 dbSNP
rs780014205 24 dbSNP
rs377005128 25 dbSNP
rs1385330489 30 dbSNP
rs369958360 31 dbSNP
rs781695584 32 dbSNP
rs770206839 35 dbSNP
rs748634251 38 dbSNP
rs572386226 42 dbSNP
rs1324010079 45 dbSNP
rs1383105125 46 dbSNP
rs773587008 48 dbSNP
rs200741332 49 dbSNP
rs770673616 50 dbSNP
rs199887251 51 dbSNP
rs148389866 65 dbSNP
rs142566815 66 dbSNP
rs892179270 68 dbSNP
rs1420787128 70 dbSNP
rs562388763 76 dbSNP
rs1477350725 80 dbSNP
rs1007912883 88 dbSNP
rs1379713630 89 dbSNP
rs1019669585 90 dbSNP
rs376491879 92 dbSNP
rs1249899133 97 dbSNP
rs1207305789 99 dbSNP
rs1197288608 100 dbSNP
rs775231177 109 dbSNP
rs1277777056 117 dbSNP
rs548112055 118 dbSNP
rs368110805 119 dbSNP
rs11602837 120 dbSNP
rs1195924527 125 dbSNP
rs982876388 128 dbSNP
rs547320609 130 dbSNP
rs1409861779 137 dbSNP
rs1331687579 138 dbSNP
rs997874676 138 dbSNP
rs765224255 139 dbSNP
rs1177524693 150 dbSNP
rs1157691694 151 dbSNP
rs1385048724 161 dbSNP
rs966801174 161 dbSNP
rs992911997 162 dbSNP
rs763703334 169 dbSNP
rs764278934 174 dbSNP
rs1184648263 175 dbSNP
rs570461528 177 dbSNP
rs1236952448 181 dbSNP
rs1481405682 183 dbSNP
rs1444061027 184 dbSNP
rs1401944438 189 dbSNP
rs1207825336 190 dbSNP
rs1326853924 206 dbSNP
rs1290027735 214 dbSNP
rs539558307 215 dbSNP
rs750713021 216 dbSNP
rs758523635 219 dbSNP
rs1441314231 223 dbSNP
rs766764981 224 dbSNP
rs980715990 228 dbSNP
rs556292108 230 dbSNP
rs1374450321 231 dbSNP
rs372033607 250 dbSNP
rs536045005 252 dbSNP
rs1052243448 256 dbSNP
rs957792557 258 dbSNP
rs1280361430 261 dbSNP
rs556114433 262 dbSNP
rs1352856790 265 dbSNP
rs751956491 267 dbSNP
rs529288093 268 dbSNP
rs1180119517 269 dbSNP
rs1473825403 277 dbSNP
rs1040795988 282 dbSNP
rs1216147356 283 dbSNP
rs1187817324 284 dbSNP
rs2293577 289 dbSNP
rs1418931409 290 dbSNP
rs1287324745 294 dbSNP
rs1320674390 294 dbSNP
rs1229483354 297 dbSNP
rs982811703 301 dbSNP
rs1296278063 302 dbSNP
rs1180569500 308 dbSNP
rs781675847 310 dbSNP
rs558094013 316 dbSNP
rs867878567 317 dbSNP
rs577950143 337 dbSNP
rs888676479 346 dbSNP
rs868687264 352 dbSNP
rs150954662 353 dbSNP
rs888405816 366 dbSNP
rs960214926 368 dbSNP
rs942793974 369 dbSNP
rs1411946757 372 dbSNP
rs11404182 375 dbSNP
rs397696692 375 dbSNP
rs993358495 384 dbSNP
rs1447576784 388 dbSNP
rs528542286 390 dbSNP
rs1030691653 398 dbSNP
rs902439927 403 dbSNP
rs1390618268 409 dbSNP
rs1244585452 416 dbSNP
rs999419774 418 dbSNP
rs1337787176 425 dbSNP
rs1359777607 425 dbSNP
rs755718524 429 dbSNP
rs191351346 433 dbSNP
rs978718912 439 dbSNP
rs541596451 444 dbSNP
rs925208067 445 dbSNP
rs1367305045 449 dbSNP
rs1335613178 455 dbSNP
rs747942670 462 dbSNP
rs1438857423 464 dbSNP
rs777135963 467 dbSNP
rs988043877 468 dbSNP
rs1480479561 476 dbSNP
rs982291260 488 dbSNP
rs2293578 490 dbSNP
rs1432566072 497 dbSNP
rs930264281 498 dbSNP
rs1192766599 509 dbSNP
rs943878730 517 dbSNP
rs948815942 531 dbSNP
rs1250748424 538 dbSNP
rs1041201288 541 dbSNP
rs984301416 544 dbSNP
rs1202336779 549 dbSNP
rs1483763419 556 dbSNP
rs558698593 557 dbSNP
rs777600578 562 dbSNP
rs1205809407 563 dbSNP
rs570504504 564 dbSNP
rs1312179352 565 dbSNP
rs1299637861 575 dbSNP
rs1185414351 576 dbSNP
rs1225737071 577 dbSNP
rs899542474 579 dbSNP
rs909917264 589 dbSNP
rs1256179490 595 dbSNP
rs932329706 596 dbSNP
rs1166936384 597 dbSNP
rs770362233 599 dbSNP
rs527538142 604 dbSNP
rs1177889018 616 dbSNP
rs1480649472 617 dbSNP
rs1410708294 622 dbSNP
rs1349708215 626 dbSNP
rs1371288557 629 dbSNP
rs1048023266 646 dbSNP
rs770676107 650 dbSNP
rs183546032 651 dbSNP
rs139729677 653 dbSNP
rs532937789 658 dbSNP
rs934039538 664 dbSNP
rs896004957 672 dbSNP
rs373951896 684 dbSNP
rs1226777684 688 dbSNP
rs1337818996 690 dbSNP
rs1051622161 692 dbSNP
rs745670715 694 dbSNP
rs1376814242 699 dbSNP
rs1338647868 700 dbSNP
rs1470088204 703 dbSNP
rs771924723 705 dbSNP
rs902320802 706 dbSNP
rs999455820 719 dbSNP
rs1458483335 720 dbSNP
rs1364021991 724 dbSNP
rs543493723 727 dbSNP
rs1421563457 737 dbSNP
rs549939208 740 dbSNP
rs970142098 742 dbSNP
rs556024405 746 dbSNP
rs1032247058 748 dbSNP
rs1247789156 760 dbSNP
rs1307456929 763 dbSNP
rs1353036230 775 dbSNP
rs893499229 776 dbSNP
rs1244096126 794 dbSNP
rs569340234 795 dbSNP
rs1253428710 799 dbSNP
rs1023837580 800 dbSNP
rs970509873 804 dbSNP
rs1003662682 807 dbSNP
rs1318219566 808 dbSNP
rs956023472 809 dbSNP
rs569737162 810 dbSNP
rs913786210 812 dbSNP
rs1208277311 813 dbSNP
rs910134272 820 dbSNP
rs975393190 821 dbSNP
rs536078280 822 dbSNP
rs1444468340 832 dbSNP
rs769194749 833 dbSNP
rs760513999 844 dbSNP
rs1485683170 847 dbSNP
rs922556691 848 dbSNP
rs965590947 849 dbSNP
rs1449121887 850 dbSNP
rs976590729 862 dbSNP
rs934109152 867 dbSNP
rs1259099794 868 dbSNP
rs375762869 870 dbSNP
rs566254675 871 dbSNP
rs1193882533 879 dbSNP
rs1374578510 884 dbSNP
rs1246807819 885 dbSNP
rs923825844 891 dbSNP
rs935132480 893 dbSNP
rs932435185 894 dbSNP
rs1173188224 895 dbSNP
rs1048116201 910 dbSNP
rs1376316911 911 dbSNP
rs1303163588 913 dbSNP
rs1436619508 917 dbSNP
rs1298921351 921 dbSNP
rs893718568 927 dbSNP
rs765404288 928 dbSNP
rs1373974775 932 dbSNP
rs909589678 934 dbSNP
rs1198683051 939 dbSNP
rs1012135574 940 dbSNP
rs1271333933 940 dbSNP
rs939679515 947 dbSNP
rs12068 951 dbSNP
rs1044736873 953 dbSNP
rs1037696077 956 dbSNP
rs896028374 957 dbSNP
rs1197457052 963 dbSNP
rs1340051172 965 dbSNP
rs1014854494 971 dbSNP
rs1361425280 977 dbSNP
rs1044540711 988 dbSNP
rs906012723 993 dbSNP
rs1283553604 1000 dbSNP
rs535370872 1001 dbSNP
rs11550055 1005 dbSNP
rs1408647417 1010 dbSNP
rs1000304482 1011 dbSNP
rs1330366008 1020 dbSNP
rs1397841215 1022 dbSNP
rs1412126702 1022 dbSNP
rs1234046132 1027 dbSNP
rs1172297849 1030 dbSNP
rs1279110716 1034 dbSNP
rs1025799483 1035 dbSNP
rs1200367966 1035 dbSNP
rs187886001 1036 dbSNP
rs1005669233 1038 dbSNP
rs1017025431 1040 dbSNP
rs964266647 1041 dbSNP
rs1033087004 1042 dbSNP
rs1212637532 1042 dbSNP
rs955542772 1045 dbSNP
rs193241154 1059 dbSNP
rs977556509 1062 dbSNP
rs956033460 1066 dbSNP
rs1336818386 1069 dbSNP
rs773130343 1076 dbSNP
rs537012138 1077 dbSNP
rs1408727906 1081 dbSNP
rs557055020 1081 dbSNP
rs1263783432 1087 dbSNP
rs1406072266 1095 dbSNP
rs1160319681 1097 dbSNP
rs1470568066 1102 dbSNP
rs1236793647 1104 dbSNP
rs762984040 1106 dbSNP
rs965297230 1107 dbSNP
rs1243516186 1108 dbSNP
rs1462635946 1108 dbSNP
rs1207881672 1116 dbSNP
rs915036768 1121 dbSNP
rs1285936418 1127 dbSNP
rs977063289 1132 dbSNP
rs947967630 1133 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124A_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + A ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aacagguaacauagACCCCUa 5'
                        |||||| 
Target 5' -------------gUGGGGAa 3'
 		1 - 8
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_124A_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + A
Location of target site ENST00000524928.1 | 3UTR | GUGGGGAAGGGCAGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD -0.573 0 -0.599 0 32 Click to see details
LUSC -0.525 0 -0.508 0 38 Click to see details
PRAD 0.339 0.01 0.201 0.08 50 Click to see details
LIHC 0.228 0.06 0.364 0.01 49 Click to see details
PAAD -0.876 0.06 -0.800 0.1 4 Click to see details
LUAD -0.439 0.08 -0.434 0.08 12 Click to see details
KIRP -0.222 0.11 -0.310 0.04 32 Click to see details
HNSC 0.146 0.18 0.118 0.23 42 Click to see details
CESC 0.74 0.23 0.500 0.33 3 Click to see details
KIRC -0.083 0.25 -0.193 0.06 68 Click to see details
BLCA 0.162 0.26 0.150 0.28 18 Click to see details
CHOL -0.184 0.32 -0.133 0.37 9 Click to see details
ESCA -0.05 0.44 0.109 0.37 11 Click to see details
UCEC 0.034 0.45 0.000 0.5 19 Click to see details
PCPG 0.131 0.46 0.500 0.33 3 Click to see details
THCA 0.01 0.47 0.019 0.44 59 Click to see details
BRCA -0.006 0.48 0.005 0.48 84 Click to see details
KICH -0.006 0.49 0.015 0.47 25 Click to see details
KICH -0.006 0.49 0.015 0.47 25 Click to see details
164 hsa-miR-2355-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT190653 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT286477 TAOK1 TAO kinase 1 2 4
MIRT318993 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT345622 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT442513 SYT7 synaptotagmin 7 2 4
MIRT444247 CTNND1 catenin delta 1 2 2
MIRT444780 ECE1 endothelin converting enzyme 1 2 2
MIRT456525 TMEM63A transmembrane protein 63A 2 2
MIRT468960 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT469834 R3HDM4 R3H domain containing 4 2 2
MIRT470027 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT471167 PHB2 prohibitin 2 2 2
MIRT475819 HDGF heparin binding growth factor 2 4
MIRT479389 CDKN1B cyclin dependent kinase inhibitor 1B 2 6
MIRT481747 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT485220 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT487259 CCNF cyclin F 2 2
MIRT489971 MCC mutated in colorectal cancers 2 4
MIRT491399 C1D C1D nuclear receptor corepressor 2 2
MIRT494959 CCDC144A coiled-coil domain containing 144A 2 4
MIRT494979 PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 2 2
MIRT495225 CHST14 carbohydrate sulfotransferase 14 2 2
MIRT496550 TBX15 T-box 15 2 2
MIRT501612 PISD phosphatidylserine decarboxylase 2 2
MIRT509393 TRIM24 tripartite motif containing 24 2 2
MIRT519616 ZNF788 zinc finger family member 788 2 4
MIRT519738 ZNF394 zinc finger protein 394 2 4
MIRT521230 SAR1A secretion associated Ras related GTPase 1A 2 4
MIRT521801 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT526233 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT526932 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT529189 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT529329 ZNF649 zinc finger protein 649 2 2
MIRT529698 MRPL30 mitochondrial ribosomal protein L30 2 2
MIRT529921 TOP1MT DNA topoisomerase I mitochondrial 2 2
MIRT530032 SMC1A structural maintenance of chromosomes 1A 2 2
MIRT530898 C9orf3 chromosome 9 open reading frame 3 2 2
MIRT531621 TM4SF5 transmembrane 4 L six family member 5 2 4
MIRT533132 XIAP X-linked inhibitor of apoptosis 2 2
MIRT533210 WAPAL WAPL cohesin release factor 2 2
MIRT534058 ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2 2
MIRT535487 PARVB parvin beta 2 2
MIRT536749 HOXD9 homeobox D9 2 2
MIRT551456 CARKD NAD(P)HX dehydratase 2 2
MIRT551858 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT552095 FAM8A1 family with sequence similarity 8 member A1 2 2
MIRT552332 ZNF704 zinc finger protein 704 2 2
MIRT552549 ZFP36L2 ZFP36 ring finger protein like 2 2 2
MIRT561505 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT562702 ZNF415 zinc finger protein 415 2 2
MIRT563052 ZNF138 zinc finger protein 138 2 2
MIRT564592 ZNF791 zinc finger protein 791 2 2
MIRT566422 PIGA phosphatidylinositol glycan anchor biosynthesis class A 2 2
MIRT570176 RCBTB1 RCC1 and BTB domain containing protein 1 2 2
MIRT570866 ZNF525 zinc finger protein 525 2 2
MIRT570875 ZFP1 ZFP1 zinc finger protein 2 2
MIRT571517 ZNF625 zinc finger protein 625 2 2
MIRT572551 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT610894 HINFP histone H4 transcription factor 2 2
MIRT611037 PTGES prostaglandin E synthase 2 2
MIRT611479 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT612419 SP1 Sp1 transcription factor 2 2
MIRT614478 FRMPD3 FERM and PDZ domain containing 3 2 2
MIRT616318 CACNA1A calcium voltage-gated channel subunit alpha1 A 2 2
MIRT616929 ZNF638 zinc finger protein 638 2 2
MIRT618131 GABARAPL3 GABA type A receptor associated protein like 3 pseudogene 2 2
MIRT618452 ZFP30 ZFP30 zinc finger protein 2 4
MIRT620671 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT620713 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT621126 EMC7 ER membrane protein complex subunit 7 2 4
MIRT621443 TOMM22 translocase of outer mitochondrial membrane 22 2 2
MIRT623491 KCTD11 potassium channel tetramerization domain containing 11 2 2
MIRT623783 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT623918 FNBP1L formin binding protein 1 like 2 2
MIRT625723 CXorf38 chromosome X open reading frame 38 2 2
MIRT625778 GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2 2
MIRT626940 TTR transthyretin 2 2
MIRT627357 TSC22D2 TSC22 domain family member 2 2 2
MIRT632078 ALDH1A2 aldehyde dehydrogenase 1 family member A2 2 2
MIRT633361 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT639793 MVK mevalonate kinase 2 2
MIRT643761 NAGK N-acetylglucosamine kinase 2 2
MIRT644358 NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 2 2
MIRT645558 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT646588 ANKRD36 ankyrin repeat domain 36 2 2
MIRT646631 SLC25A46 solute carrier family 25 member 46 2 2
MIRT648066 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT648142 SUCLG2 succinate-CoA ligase GDP-forming beta subunit 2 2
MIRT648416 MYOZ3 myozenin 3 2 2
MIRT649218 AMMECR1L AMMECR1 like 2 2
MIRT649772 MRPS27 mitochondrial ribosomal protein S27 2 4
MIRT650510 UFM1 ubiquitin fold modifier 1 2 2
MIRT651007 ZNF740 zinc finger protein 740 2 2
MIRT651524 WNT2B Wnt family member 2B 2 2
MIRT652014 TTYH3 tweety family member 3 2 2
MIRT652513 TMEM109 transmembrane protein 109 2 2
MIRT652686 THUMPD3 THUMP domain containing 3 2 2
MIRT652772 TENM3 teneurin transmembrane protein 3 2 2
MIRT653160 SPRY4 sprouty RTK signaling antagonist 4 2 2
MIRT653765 SIX5 SIX homeobox 5 2 2
MIRT653792 SIRPA signal regulatory protein alpha 2 2
MIRT655649 OAZ2 ornithine decarboxylase antizyme 2 2 2
MIRT656263 MEX3A mex-3 RNA binding family member A 2 2
MIRT657044 KCNH6 potassium voltage-gated channel subfamily H member 6 2 2
MIRT657375 HMGA1 high mobility group AT-hook 1 2 2
MIRT657532 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT657542 GSTO2 glutathione S-transferase omega 2 2 2
MIRT657828 GJD3 gap junction protein delta 3 2 2
MIRT658946 DOK6 docking protein 6 2 2
MIRT660363 BACH2 BTB domain and CNC homolog 2 2 2
MIRT660406 ATXN7L3 ataxin 7 like 3 2 2
MIRT660948 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT661031 AAK1 AP2 associated kinase 1 2 2
MIRT662435 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT668419 FAM217B family with sequence similarity 217 member B 2 2
MIRT669332 BSND barttin CLCNK type accessory beta subunit 2 2
MIRT676105 CLUAP1 clusterin associated protein 1 2 2
MIRT677084 SMIM15 small integral membrane protein 15 2 2
MIRT677127 OGFOD3 2-oxoglutarate and iron dependent oxygenase domain containing 3 2 2
MIRT678001 CPM carboxypeptidase M 2 2
MIRT678531 TMEM78 transmembrane protein 78 2 2
MIRT680000 ZNF860 zinc finger protein 860 2 2
MIRT680098 PXMP4 peroxisomal membrane protein 4 2 2
MIRT686795 SOX12 SRY-box 12 2 2
MIRT698887 SPTBN2 spectrin beta, non-erythrocytic 2 2 2
MIRT699371 SLC30A6 solute carrier family 30 member 6 2 2
MIRT702005 MIDN midnolin 2 2
MIRT708101 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT709563 GYG2 glycogenin 2 2 2
MIRT710559 PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon 2 2
MIRT710585 CDCA4 cell division cycle associated 4 2 2
MIRT710873 NT5DC1 5'-nucleotidase domain containing 1 2 2
MIRT711876 VASP vasodilator stimulated phosphoprotein 2 2
MIRT712226 RIMS3 regulating synaptic membrane exocytosis 3 2 2
MIRT713211 FAM13A family with sequence similarity 13 member A 2 2
MIRT713261 GPR55 G protein-coupled receptor 55 2 2
MIRT713327 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT713889 RNF19B ring finger protein 19B 2 2
MIRT714015 UBAP2L ubiquitin associated protein 2 like 2 2
MIRT714202 NLRP12 NLR family pyrin domain containing 12 2 2
MIRT714717 VPS8 VPS8, CORVET complex subunit 2 2
MIRT714748 ZNF385D zinc finger protein 385D 2 2
MIRT714806 ARHGEF19 Rho guanine nucleotide exchange factor 19 2 2
MIRT714852 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 2 2
MIRT715717 MRPL4 mitochondrial ribosomal protein L4 2 2
MIRT715852 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT716853 MFSD12 major facilitator superfamily domain containing 12 2 2
MIRT717134 EBPL emopamil binding protein like 2 2
MIRT717248 TMEM246 transmembrane protein 246 2 2
MIRT717997 ZNF79 zinc finger protein 79 2 2
MIRT718341 PURA purine rich element binding protein A 2 2
MIRT719587 TFCP2L1 transcription factor CP2 like 1 2 2
MIRT720520 PTGR2 prostaglandin reductase 2 2 2
MIRT720671 SLC39A13 solute carrier family 39 member 13 2 2
MIRT721213 DCLK3 doublecortin like kinase 3 2 2
MIRT721757 INF2 inverted formin, FH2 and WH2 domain containing 2 2
MIRT721826 POU6F1 POU class 6 homeobox 1 2 2
MIRT722091 SUSD1 sushi domain containing 1 2 2
MIRT722275 LURAP1 leucine rich adaptor protein 1 2 2
MIRT722802 ARHGAP19 Rho GTPase activating protein 19 2 2
MIRT722866 FAM212B family with sequence similarity 212 member B 2 2
MIRT723113 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT724378 NEK8 NIMA related kinase 8 2 2
MIRT732775 PYCR1 pyrroline-5-carboxylate reductase 1 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-2355 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-2355-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-2355-5p Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-2355-5p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-2355-5p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-2355-5p Temozolomide 5394 NSC362856 approved resistant High Glioma tissue
hsa-miR-2355-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-2355-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-2355-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-2355-5p Tamoxifen+Fulvestrant sensitive cell line (LCC9)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-2355-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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