pre-miRNA Information
pre-miRNA hsa-mir-2355   
Genomic Coordinates chr2: 207109987 - 207110073
Description Homo sapiens miR-2355 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-2355-5p
Sequence 11| AUCCCCAGAUACAAUGGACAA |31
Evidence Experimental
Experiments SOLiD
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 1 2 - 207110063 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1268296297 4 dbSNP
rs1361046879 5 dbSNP
rs1219551997 6 dbSNP
rs1295756820 12 dbSNP
rs1345273529 15 dbSNP
rs977145706 15 dbSNP
rs1209629984 20 dbSNP
rs759940260 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NEK8   
Synonyms JCK, NEK12A, NPHP9, RHPD2
Description NIMA related kinase 8
Transcript NM_178170   
Expression
Putative miRNA Targets on NEK8
3'UTR of NEK8
(miRNA target sites are highlighted)
>NEK8|NM_178170|3'UTR
   1 GGCACCCGGATTCACCTCTGGACCACCCTGATATTGCTTCTCCTCTGAATGCTCTGAAAAGTGCAGGTGCCCAAGGCATG
  81 ACTTGCAGCTGTCTCCTGGATTGTGTCATCATGGGGTATCAGGGCTGGCAAAACCCCTGCTCTGCTTTTGGCCTTGGATA
 161 TGGAAACCTCAACCACTTTGTTCTCCTACCACCTCTTTGCCCTTCCTACCCCTTCCTCCCTTCAGTCAGTGTCCCCAGGG
 241 TCCAGCCTGGCTAGAGTTAGAAGGCAGACCTAGCCTTTGGAAGCAGGGTGGCCTCCAGAGCCTTGCCATAAAAAGGCTGA
 321 AGGCAGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGA
 401 TCGAGACCATCCTGGCTAACGTGGTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGGTGGCACGCG
 481 CCTGTAGTCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAATGGCGTAAACCCCTCCAGCCTGGGCGACAGAACCAGACTCC
 561 GTCTCAAAAAAAAAAAAAAAACAAAAAAGGCTGAAGGCAGCTGTAGCTCCACACAGACCCTACCCTTTCCCCTAGCCCAG
 641 TTAGAAAATAAGTCTGGGCCGGCGGCGGTGGCTCACACCTGCATAGGCAGTGCTTTGGCCAGGAGGATCCCTTGATCCCT
 721 TGTGGCCAGGAGTTGGGAGACCAGCCTGGGGACCATAGCGAGACCGCTGTCTCCACCAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' aaCAGGUAACAUAGACCCCUa 5'
            | |||    : ||||||| 
Target 5' gaGACCA----GCCTGGGGAc 3'
737 - 753 141.00 -14.00
2
miRNA  3' aacAGG---UAACA---UAG-ACCCCua 5'
             |||   |||||   ||| |||||  
Target 5' gtcTCCTGGATTGTGTCATCATGGGGta 3'
91 - 118 114.00 -16.00
3
miRNA  3' aacAGGUAACAUAGACCC-CUa 5'
             ||||    : ||||| || 
Target 5' cccTCCA----GCCTGGGCGAc 3'
530 - 547 112.00 -10.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
889768 20 ClinVar
322488 157 ClinVar
322489 164 ClinVar
322490 329 ClinVar
322491 339 ClinVar
322492 345 ClinVar
322493 382 ClinVar
891304 383 ClinVar
322494 389 ClinVar
322495 397 ClinVar
322496 421 ClinVar
322497 422 ClinVar
322498 431 ClinVar
892498 475 ClinVar
322499 481 ClinVar
892499 524 ClinVar
892500 527 ClinVar
892501 575 ClinVar
889134 576 ClinVar
322500 579 ClinVar
889135 583 ClinVar
889136 638 ClinVar
322501 667 ClinVar
889137 760 ClinVar
322502 764 ClinVar
COSN31497845 9 COSMIC
COSN30507176 10 COSMIC
COSN30145952 22 COSMIC
COSN30188074 34 COSMIC
COSN26578254 43 COSMIC
COSN30158257 43 COSMIC
COSN31510363 72 COSMIC
COSN30661911 140 COSMIC
COSN28865364 265 COSMIC
COSN25325671 270 COSMIC
COSN23464689 330 COSMIC
COSN26764587 437 COSMIC
COSN8834077 908 COSMIC
rs1142899 389 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1355881390 2 dbSNP
rs753790736 3 dbSNP
rs754910336 6 dbSNP
rs1339870555 7 dbSNP
rs906093464 8 dbSNP
rs778937777 9 dbSNP
rs747845325 10 dbSNP
rs1227431235 12 dbSNP
rs758199115 14 dbSNP
rs75850216 20 dbSNP
rs1463275737 21 dbSNP
rs747292987 22 dbSNP
rs1286425949 25 dbSNP
rs770978998 26 dbSNP
rs776616457 28 dbSNP
rs745992731 29 dbSNP
rs376340694 30 dbSNP
rs1444204960 31 dbSNP
rs770151835 35 dbSNP
rs549334189 38 dbSNP
rs767202440 40 dbSNP
rs758502952 42 dbSNP
rs763161031 44 dbSNP
rs1047557678 46 dbSNP
rs1170653843 47 dbSNP
rs983155647 54 dbSNP
rs912000224 77 dbSNP
rs944782524 83 dbSNP
rs1290002301 88 dbSNP
rs1221340249 89 dbSNP
rs1018698048 92 dbSNP
rs567544609 98 dbSNP
rs141685281 103 dbSNP
rs921774760 113 dbSNP
rs1340199670 115 dbSNP
rs1482079105 119 dbSNP
rs547724376 121 dbSNP
rs1197753432 126 dbSNP
rs946619609 127 dbSNP
rs1343453253 136 dbSNP
rs111495213 137 dbSNP
rs1364501601 153 dbSNP
rs1276801131 156 dbSNP
rs186791558 157 dbSNP
rs886052768 164 dbSNP
rs537767687 170 dbSNP
rs923918420 175 dbSNP
rs1424328045 188 dbSNP
rs1212052225 204 dbSNP
rs934648699 206 dbSNP
rs1477122669 213 dbSNP
rs1193665104 215 dbSNP
rs1363757711 217 dbSNP
rs902731432 218 dbSNP
rs1053076121 226 dbSNP
rs999667079 227 dbSNP
rs895887986 228 dbSNP
rs950157838 235 dbSNP
rs1044515032 236 dbSNP
rs1169242401 243 dbSNP
rs959810390 255 dbSNP
rs1013985243 259 dbSNP
rs539513821 269 dbSNP
rs557808408 271 dbSNP
rs906035692 276 dbSNP
rs995061746 293 dbSNP
rs1321319162 308 dbSNP
rs1282473433 322 dbSNP
rs1023093118 326 dbSNP
rs1346409195 328 dbSNP
rs191309632 329 dbSNP
rs1384409463 330 dbSNP
rs146209770 332 dbSNP
rs1377114451 333 dbSNP
rs886727293 334 dbSNP
rs575583062 335 dbSNP
rs1427738619 336 dbSNP
rs555831494 339 dbSNP
rs1176184049 343 dbSNP
rs537387525 345 dbSNP
rs1294831687 346 dbSNP
rs1327049537 350 dbSNP
rs950592804 362 dbSNP
rs1273234196 368 dbSNP
rs983299128 372 dbSNP
rs1459935367 373 dbSNP
rs1347448730 374 dbSNP
rs555690853 378 dbSNP
rs1018639615 379 dbSNP
rs540677227 382 dbSNP
rs1039107679 383 dbSNP
rs956240372 385 dbSNP
rs1225590616 387 dbSNP
rs1142899 389 dbSNP
rs886052769 397 dbSNP
rs1319066128 398 dbSNP
rs1437301751 403 dbSNP
rs577837205 404 dbSNP
rs1028786641 410 dbSNP
rs183805648 421 dbSNP
rs886052770 422 dbSNP
rs1043682433 423 dbSNP
rs923838743 424 dbSNP
rs956671336 427 dbSNP
rs4795455 431 dbSNP
rs1056580461 435 dbSNP
rs372192000 442 dbSNP
rs1396637808 451 dbSNP
rs1417655771 455 dbSNP
rs917264101 468 dbSNP
rs575552986 469 dbSNP
rs112096840 475 dbSNP
rs1044463904 477 dbSNP
rs193042078 478 dbSNP
rs930800533 479 dbSNP
rs1327274293 480 dbSNP
rs1379680449 480 dbSNP
rs1409700321 480 dbSNP
rs528347456 481 dbSNP
rs1170135795 484 dbSNP
rs1442367966 486 dbSNP
rs1441880906 497 dbSNP
rs1183662546 498 dbSNP
rs1049258516 505 dbSNP
rs886672427 513 dbSNP
rs1027296183 522 dbSNP
rs149884715 524 dbSNP
rs1276479454 525 dbSNP
rs1351907312 527 dbSNP
rs1357536666 528 dbSNP
rs1291218751 529 dbSNP
rs747326024 531 dbSNP
rs1238824843 538 dbSNP
rs1381986401 539 dbSNP
rs1278252398 543 dbSNP
rs1442073597 545 dbSNP
rs1261778496 546 dbSNP
rs1310223765 547 dbSNP
rs1422431476 556 dbSNP
rs1364493629 559 dbSNP
rs559348442 561 dbSNP
rs542810888 562 dbSNP
rs1167772894 566 dbSNP
rs1197012094 566 dbSNP
rs1253784293 566 dbSNP
rs1435876664 566 dbSNP
rs965911942 566 dbSNP
rs1268378578 573 dbSNP
rs974940888 575 dbSNP
rs922057276 576 dbSNP
rs1193814332 577 dbSNP
rs946761524 578 dbSNP
rs1290602464 579 dbSNP
rs185303602 579 dbSNP
rs1344495978 582 dbSNP
rs114252148 583 dbSNP
rs923925667 583 dbSNP
rs935624682 584 dbSNP
rs1157719449 590 dbSNP
rs1401283114 596 dbSNP
rs1254497779 610 dbSNP
rs1414009105 618 dbSNP
rs35566755 618 dbSNP
rs1005151314 627 dbSNP
rs1158130750 629 dbSNP
rs1429694793 632 dbSNP
rs114191927 638 dbSNP
rs569810159 643 dbSNP
rs1489579779 656 dbSNP
rs1240497405 659 dbSNP
rs1455253095 661 dbSNP
rs1161454099 662 dbSNP
rs1270519253 663 dbSNP
rs1222095608 664 dbSNP
rs1323330008 665 dbSNP
rs886052771 667 dbSNP
rs1220657833 668 dbSNP
rs901510145 681 dbSNP
rs995879169 688 dbSNP
rs1441747207 694 dbSNP
rs537248931 697 dbSNP
rs1045619432 699 dbSNP
rs1390777599 704 dbSNP
rs905626838 716 dbSNP
rs1359583125 720 dbSNP
rs994577181 720 dbSNP
rs1177960738 722 dbSNP
rs549513388 724 dbSNP
rs1391092132 725 dbSNP
rs1186023273 728 dbSNP
rs1450116872 730 dbSNP
rs1249947925 735 dbSNP
rs1027349806 736 dbSNP
rs1461255466 740 dbSNP
rs1257026674 749 dbSNP
rs1212605794 751 dbSNP
rs886105948 756 dbSNP
rs1004515193 757 dbSNP
rs1228540616 760 dbSNP
rs886052772 764 dbSNP
rs1337973476 765 dbSNP
rs1402740985 766 dbSNP
rs1243237701 767 dbSNP
rs1273123665 768 dbSNP
rs1353005108 770 dbSNP
rs1168236517 775 dbSNP
rs1018863304 778 dbSNP
rs1251085022 778 dbSNP
rs1257411075 778 dbSNP
rs1430624533 778 dbSNP
rs752579944 778 dbSNP
rs777796997 778 dbSNP
rs966331062 778 dbSNP
rs1333434155 788 dbSNP
rs1205501623 791 dbSNP
rs1288963753 791 dbSNP
rs974614088 791 dbSNP
rs1213803936 792 dbSNP
rs1029229002 793 dbSNP
rs1479440157 794 dbSNP
rs1176305347 797 dbSNP
rs1389570290 797 dbSNP
rs968182171 801 dbSNP
rs1044487197 802 dbSNP
rs979483168 807 dbSNP
rs1410744339 809 dbSNP
rs1372573250 812 dbSNP
rs769032910 814 dbSNP
rs567876898 815 dbSNP
rs1369583729 820 dbSNP
rs1167579429 823 dbSNP
rs1185249387 824 dbSNP
rs923977889 825 dbSNP
rs935341899 826 dbSNP
rs1417124016 830 dbSNP
rs1461988961 852 dbSNP
rs1167169601 853 dbSNP
rs1398255152 858 dbSNP
rs113012137 864 dbSNP
rs992080759 867 dbSNP
rs1288758267 868 dbSNP
rs1461668865 868 dbSNP
rs918195189 872 dbSNP
rs1029150461 873 dbSNP
rs920071067 874 dbSNP
rs1399014043 875 dbSNP
rs930421797 877 dbSNP
rs7207132 881 dbSNP
rs1295356092 883 dbSNP
rs535294074 888 dbSNP
rs1411796992 889 dbSNP
rs967850563 890 dbSNP
rs1350615561 892 dbSNP
rs756052649 908 dbSNP
rs1394658405 911 dbSNP
rs1197780394 914 dbSNP
rs1293170391 915 dbSNP
rs1356682310 916 dbSNP
rs1001086505 918 dbSNP
rs1294558242 924 dbSNP
rs1202789695 932 dbSNP
rs886148474 938 dbSNP
rs1004567374 942 dbSNP
rs1230036833 953 dbSNP
rs1305323766 955 dbSNP
rs1321208948 955 dbSNP
rs770059563 956 dbSNP
rs1251539227 959 dbSNP
rs956595985 963 dbSNP
rs1380552271 967 dbSNP
rs992046381 971 dbSNP
rs1321848537 985 dbSNP
rs1459262976 988 dbSNP
rs967846956 1004 dbSNP
rs1208498759 1006 dbSNP
rs1404433392 1011 dbSNP
rs917210769 1012 dbSNP
rs553371561 1015 dbSNP
rs1478156236 1017 dbSNP
rs1378948774 1018 dbSNP
rs919386045 1020 dbSNP
rs577750688 1025 dbSNP
rs1298770898 1028 dbSNP
rs1448308798 1034 dbSNP
rs1248074471 1038 dbSNP
rs1256607430 1041 dbSNP
rs1459921773 1060 dbSNP
rs1277658350 1063 dbSNP
rs1200760952 1066 dbSNP
rs190545060 1068 dbSNP
rs1190067171 1072 dbSNP
rs956765248 1076 dbSNP
rs1364607456 1085 dbSNP
rs1165833078 1086 dbSNP
rs1188034088 1086 dbSNP
rs1189861733 1086 dbSNP
rs1203349585 1086 dbSNP
rs1230631574 1086 dbSNP
rs1236781440 1086 dbSNP
rs1270591109 1086 dbSNP
rs1275453035 1086 dbSNP
rs1298400493 1086 dbSNP
rs1327255085 1086 dbSNP
rs1341714546 1086 dbSNP
rs1342687316 1086 dbSNP
rs1370726895 1086 dbSNP
rs1390313837 1086 dbSNP
rs1408842123 1086 dbSNP
rs1428683235 1086 dbSNP
rs1437988568 1086 dbSNP
rs1442715319 1086 dbSNP
rs1443964854 1086 dbSNP
rs1449360863 1086 dbSNP
rs562419288 1086 dbSNP
rs60028464 1086 dbSNP
rs750008626 1086 dbSNP
rs753603697 1086 dbSNP
rs758242914 1086 dbSNP
rs780514321 1086 dbSNP
rs1428010258 1087 dbSNP
rs1171317079 1088 dbSNP
rs1375033726 1089 dbSNP
rs1464814761 1090 dbSNP
rs1312628482 1091 dbSNP
rs1376483929 1092 dbSNP
rs1417154264 1093 dbSNP
rs1296947518 1094 dbSNP
rs1359177117 1095 dbSNP
rs1213478236 1096 dbSNP
rs1169961444 1099 dbSNP
rs1295791582 1099 dbSNP
rs1422170748 1100 dbSNP
rs992133168 1109 dbSNP
rs1308874794 1113 dbSNP
rs1231679167 1114 dbSNP
rs917899567 1115 dbSNP
rs1181110702 1116 dbSNP
rs969692313 1116 dbSNP
rs374981170 1117 dbSNP
rs1207426001 1118 dbSNP
rs1485910720 1118 dbSNP
rs1212864686 1120 dbSNP
rs981430058 1122 dbSNP
rs1229454679 1123 dbSNP
rs1485561636 1125 dbSNP
rs1359073850 1131 dbSNP
rs1233714347 1132 dbSNP
rs572804997 1133 dbSNP
rs980162618 1138 dbSNP
rs1421800553 1139 dbSNP
rs927358742 1141 dbSNP
rs931469055 1143 dbSNP
rs1339961462 1152 dbSNP
rs930769804 1153 dbSNP
rs1407017135 1157 dbSNP
rs1405631664 1160 dbSNP
rs1158180631 1169 dbSNP
rs950835645 1170 dbSNP
rs1413869358 1172 dbSNP
rs1049666135 1176 dbSNP
rs1487620664 1182 dbSNP
rs1246271792 1185 dbSNP
rs1173317421 1186 dbSNP
rs908041861 1199 dbSNP
rs1266737313 1208 dbSNP
rs940884307 1209 dbSNP
rs557142625 1211 dbSNP
rs1330298288 1212 dbSNP
rs1040646369 1216 dbSNP
rs907636229 1217 dbSNP
rs1217183400 1219 dbSNP
rs902128554 1228 dbSNP
rs995826787 1234 dbSNP
rs940407409 1235 dbSNP
rs1437933129 1236 dbSNP
rs1386403155 1238 dbSNP
rs1050119662 1247 dbSNP
rs1040062667 1248 dbSNP
rs1345146337 1254 dbSNP
rs901502596 1260 dbSNP
rs996142105 1264 dbSNP
rs903574848 1265 dbSNP
rs1050778914 1275 dbSNP
rs1000635095 1276 dbSNP
rs1288914779 1286 dbSNP
rs1000673362 1287 dbSNP
rs1191876299 1291 dbSNP
rs182077269 1296 dbSNP
rs1438245247 1302 dbSNP
rs1302255060 1305 dbSNP
rs956816299 1320 dbSNP
rs1465737619 1322 dbSNP
rs1270418998 1339 dbSNP
rs1348245184 1349 dbSNP
rs956543505 1350 dbSNP
rs1236261212 1351 dbSNP
rs1013414069 1355 dbSNP
rs1014070668 1367 dbSNP
rs1311276368 1368 dbSNP
rs1025015846 1369 dbSNP
rs1362468116 1370 dbSNP
rs1296211069 1371 dbSNP
rs1435810692 1372 dbSNP
rs1024840440 1373 dbSNP
rs1465324154 1374 dbSNP
rs544999776 1374 dbSNP
rs980493028 1376 dbSNP
rs920192199 1379 dbSNP
rs1187929544 1389 dbSNP
rs952908867 1397 dbSNP
rs542468316 1403 dbSNP
rs1180513686 1408 dbSNP
rs1483153194 1412 dbSNP
rs1238392529 1423 dbSNP
rs1467240676 1425 dbSNP
rs1034373688 1427 dbSNP
rs982975700 1438 dbSNP
rs952192438 1439 dbSNP
rs908690962 1443 dbSNP
rs1193176311 1448 dbSNP
rs940459963 1459 dbSNP
rs984896489 1465 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124A_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + A ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' aacagguaacauaGACCC-CUa 5'
                       :|||| || 
Target 5' ------------gUUGGGAGAc 3'
1 - 10
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_124A_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + A
Location of target site ENST00000268766.6 | 3UTR | GUUGGGAGACCAGCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
UCEC -0.589 0 -0.488 0.02 19 Click to see details
LUAD 0.544 0.03 0.448 0.07 12 Click to see details
KIRC -0.182 0.07 -0.189 0.06 68 Click to see details
STAD 0.262 0.07 0.198 0.14 32 Click to see details
PRAD -0.19 0.09 -0.238 0.05 50 Click to see details
THCA -0.163 0.11 -0.187 0.08 59 Click to see details
LUSC -0.181 0.14 -0.168 0.16 38 Click to see details
BRCA -0.112 0.16 -0.161 0.07 84 Click to see details
PAAD 0.685 0.16 0.600 0.2 4 Click to see details
BLCA 0.207 0.2 0.092 0.36 18 Click to see details
ESCA -0.147 0.33 -0.018 0.48 11 Click to see details
KIRP -0.064 0.36 -0.118 0.26 32 Click to see details
LIHC -0.043 0.38 0.063 0.33 49 Click to see details
KICH -0.05 0.41 -0.064 0.38 25 Click to see details
CESC -0.239 0.42 -0.500 0.33 3 Click to see details
CHOL 0.036 0.46 0.033 0.47 9 Click to see details
PCPG -0.057 0.48 -0.500 0.33 3 Click to see details
HNSC 0.002 0.49 0.053 0.37 42 Click to see details
HNSC 0.002 0.49 0.053 0.37 42 Click to see details
164 hsa-miR-2355-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT190653 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT286477 TAOK1 TAO kinase 1 2 4
MIRT318993 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT345622 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT442513 SYT7 synaptotagmin 7 2 4
MIRT444247 CTNND1 catenin delta 1 2 2
MIRT444780 ECE1 endothelin converting enzyme 1 2 2
MIRT456525 TMEM63A transmembrane protein 63A 2 2
MIRT468960 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT469834 R3HDM4 R3H domain containing 4 2 2
MIRT470027 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT471167 PHB2 prohibitin 2 2 2
MIRT475819 HDGF heparin binding growth factor 2 4
MIRT479389 CDKN1B cyclin dependent kinase inhibitor 1B 2 6
MIRT481747 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT485220 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT487259 CCNF cyclin F 2 2
MIRT489971 MCC mutated in colorectal cancers 2 4
MIRT491399 C1D C1D nuclear receptor corepressor 2 2
MIRT494959 CCDC144A coiled-coil domain containing 144A 2 4
MIRT494979 PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 2 2
MIRT495225 CHST14 carbohydrate sulfotransferase 14 2 2
MIRT496550 TBX15 T-box 15 2 2
MIRT501612 PISD phosphatidylserine decarboxylase 2 2
MIRT509393 TRIM24 tripartite motif containing 24 2 2
MIRT519616 ZNF788 zinc finger family member 788 2 4
MIRT519738 ZNF394 zinc finger protein 394 2 4
MIRT521230 SAR1A secretion associated Ras related GTPase 1A 2 4
MIRT521801 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT526233 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT526932 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT529189 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT529329 ZNF649 zinc finger protein 649 2 2
MIRT529698 MRPL30 mitochondrial ribosomal protein L30 2 2
MIRT529921 TOP1MT DNA topoisomerase I mitochondrial 2 2
MIRT530032 SMC1A structural maintenance of chromosomes 1A 2 2
MIRT530898 C9orf3 chromosome 9 open reading frame 3 2 2
MIRT531621 TM4SF5 transmembrane 4 L six family member 5 2 4
MIRT533132 XIAP X-linked inhibitor of apoptosis 2 2
MIRT533210 WAPAL WAPL cohesin release factor 2 2
MIRT534058 ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2 2
MIRT535487 PARVB parvin beta 2 2
MIRT536749 HOXD9 homeobox D9 2 2
MIRT551456 CARKD NAD(P)HX dehydratase 2 2
MIRT551858 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT552095 FAM8A1 family with sequence similarity 8 member A1 2 2
MIRT552332 ZNF704 zinc finger protein 704 2 2
MIRT552549 ZFP36L2 ZFP36 ring finger protein like 2 2 2
MIRT561505 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT562702 ZNF415 zinc finger protein 415 2 2
MIRT563052 ZNF138 zinc finger protein 138 2 2
MIRT564592 ZNF791 zinc finger protein 791 2 2
MIRT566422 PIGA phosphatidylinositol glycan anchor biosynthesis class A 2 2
MIRT570176 RCBTB1 RCC1 and BTB domain containing protein 1 2 2
MIRT570866 ZNF525 zinc finger protein 525 2 2
MIRT570875 ZFP1 ZFP1 zinc finger protein 2 2
MIRT571517 ZNF625 zinc finger protein 625 2 2
MIRT572551 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT610894 HINFP histone H4 transcription factor 2 2
MIRT611037 PTGES prostaglandin E synthase 2 2
MIRT611479 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT612419 SP1 Sp1 transcription factor 2 2
MIRT614478 FRMPD3 FERM and PDZ domain containing 3 2 2
MIRT616318 CACNA1A calcium voltage-gated channel subunit alpha1 A 2 2
MIRT616929 ZNF638 zinc finger protein 638 2 2
MIRT618131 GABARAPL3 GABA type A receptor associated protein like 3 pseudogene 2 2
MIRT618452 ZFP30 ZFP30 zinc finger protein 2 4
MIRT620671 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT620713 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT621126 EMC7 ER membrane protein complex subunit 7 2 4
MIRT621443 TOMM22 translocase of outer mitochondrial membrane 22 2 2
MIRT623491 KCTD11 potassium channel tetramerization domain containing 11 2 2
MIRT623783 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT623918 FNBP1L formin binding protein 1 like 2 2
MIRT625723 CXorf38 chromosome X open reading frame 38 2 2
MIRT625778 GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2 2
MIRT626940 TTR transthyretin 2 2
MIRT627357 TSC22D2 TSC22 domain family member 2 2 2
MIRT632078 ALDH1A2 aldehyde dehydrogenase 1 family member A2 2 2
MIRT633361 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT639793 MVK mevalonate kinase 2 2
MIRT643761 NAGK N-acetylglucosamine kinase 2 2
MIRT644358 NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 2 2
MIRT645558 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT646588 ANKRD36 ankyrin repeat domain 36 2 2
MIRT646631 SLC25A46 solute carrier family 25 member 46 2 2
MIRT648066 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT648142 SUCLG2 succinate-CoA ligase GDP-forming beta subunit 2 2
MIRT648416 MYOZ3 myozenin 3 2 2
MIRT649218 AMMECR1L AMMECR1 like 2 2
MIRT649772 MRPS27 mitochondrial ribosomal protein S27 2 4
MIRT650510 UFM1 ubiquitin fold modifier 1 2 2
MIRT651007 ZNF740 zinc finger protein 740 2 2
MIRT651524 WNT2B Wnt family member 2B 2 2
MIRT652014 TTYH3 tweety family member 3 2 2
MIRT652513 TMEM109 transmembrane protein 109 2 2
MIRT652686 THUMPD3 THUMP domain containing 3 2 2
MIRT652772 TENM3 teneurin transmembrane protein 3 2 2
MIRT653160 SPRY4 sprouty RTK signaling antagonist 4 2 2
MIRT653765 SIX5 SIX homeobox 5 2 2
MIRT653792 SIRPA signal regulatory protein alpha 2 2
MIRT655649 OAZ2 ornithine decarboxylase antizyme 2 2 2
MIRT656263 MEX3A mex-3 RNA binding family member A 2 2
MIRT657044 KCNH6 potassium voltage-gated channel subfamily H member 6 2 2
MIRT657375 HMGA1 high mobility group AT-hook 1 2 2
MIRT657532 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT657542 GSTO2 glutathione S-transferase omega 2 2 2
MIRT657828 GJD3 gap junction protein delta 3 2 2
MIRT658946 DOK6 docking protein 6 2 2
MIRT660363 BACH2 BTB domain and CNC homolog 2 2 2
MIRT660406 ATXN7L3 ataxin 7 like 3 2 2
MIRT660948 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT661031 AAK1 AP2 associated kinase 1 2 2
MIRT662435 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT668419 FAM217B family with sequence similarity 217 member B 2 2
MIRT669332 BSND barttin CLCNK type accessory beta subunit 2 2
MIRT676105 CLUAP1 clusterin associated protein 1 2 2
MIRT677084 SMIM15 small integral membrane protein 15 2 2
MIRT677127 OGFOD3 2-oxoglutarate and iron dependent oxygenase domain containing 3 2 2
MIRT678001 CPM carboxypeptidase M 2 2
MIRT678531 TMEM78 transmembrane protein 78 2 2
MIRT680000 ZNF860 zinc finger protein 860 2 2
MIRT680098 PXMP4 peroxisomal membrane protein 4 2 2
MIRT686795 SOX12 SRY-box 12 2 2
MIRT698887 SPTBN2 spectrin beta, non-erythrocytic 2 2 2
MIRT699371 SLC30A6 solute carrier family 30 member 6 2 2
MIRT702005 MIDN midnolin 2 2
MIRT708101 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT709563 GYG2 glycogenin 2 2 2
MIRT710559 PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon 2 2
MIRT710585 CDCA4 cell division cycle associated 4 2 2
MIRT710873 NT5DC1 5'-nucleotidase domain containing 1 2 2
MIRT711876 VASP vasodilator stimulated phosphoprotein 2 2
MIRT712226 RIMS3 regulating synaptic membrane exocytosis 3 2 2
MIRT713211 FAM13A family with sequence similarity 13 member A 2 2
MIRT713261 GPR55 G protein-coupled receptor 55 2 2
MIRT713327 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT713889 RNF19B ring finger protein 19B 2 2
MIRT714015 UBAP2L ubiquitin associated protein 2 like 2 2
MIRT714202 NLRP12 NLR family pyrin domain containing 12 2 2
MIRT714717 VPS8 VPS8, CORVET complex subunit 2 2
MIRT714748 ZNF385D zinc finger protein 385D 2 2
MIRT714806 ARHGEF19 Rho guanine nucleotide exchange factor 19 2 2
MIRT714852 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 2 2
MIRT715717 MRPL4 mitochondrial ribosomal protein L4 2 2
MIRT715852 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT716853 MFSD12 major facilitator superfamily domain containing 12 2 2
MIRT717134 EBPL emopamil binding protein like 2 2
MIRT717248 TMEM246 transmembrane protein 246 2 2
MIRT717997 ZNF79 zinc finger protein 79 2 2
MIRT718341 PURA purine rich element binding protein A 2 2
MIRT719587 TFCP2L1 transcription factor CP2 like 1 2 2
MIRT720520 PTGR2 prostaglandin reductase 2 2 2
MIRT720671 SLC39A13 solute carrier family 39 member 13 2 2
MIRT721213 DCLK3 doublecortin like kinase 3 2 2
MIRT721757 INF2 inverted formin, FH2 and WH2 domain containing 2 2
MIRT721826 POU6F1 POU class 6 homeobox 1 2 2
MIRT722091 SUSD1 sushi domain containing 1 2 2
MIRT722275 LURAP1 leucine rich adaptor protein 1 2 2
MIRT722802 ARHGAP19 Rho GTPase activating protein 19 2 2
MIRT722866 FAM212B family with sequence similarity 212 member B 2 2
MIRT723113 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT724378 NEK8 NIMA related kinase 8 2 2
MIRT732775 PYCR1 pyrroline-5-carboxylate reductase 1 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-2355 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-2355-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-2355-5p Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-2355-5p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-2355-5p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-2355-5p Temozolomide 5394 NSC362856 approved resistant High Glioma tissue
hsa-miR-2355-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-2355-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-2355-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-2355-5p Tamoxifen+Fulvestrant sensitive cell line (LCC9)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-2355-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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