miRTarBase - #MIRT725187


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pre-miRNA Information
pre-miRNA hsa-mir-548am   
Genomic Coordinates chrX: 16627012 - 16627085
Description Homo sapiens miR-548am stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548am-5p
Sequence 10| AAAAGUAAUUGCGGUUUUUGCC |31
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 X - 16627074 29233923 MiREDiBase
A-to-I 4 X - 16627073 29233923 MiREDiBase
A-to-I 7 X - 16627070 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs181147953 1 dbSNP
rs1023899452 12 dbSNP
rs1319380894 14 dbSNP
rs768483765 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SDAD1   
Synonyms -
Description SDA1 domain containing 1
Transcript NM_018115   
Expression
Putative miRNA Targets on SDAD1
3'UTR of SDAD1
(miRNA target sites are highlighted)		 
>SDAD1|NM_018115|3'UTR
   1 CTTCCTGGCAAGTTTTCCATTCCTAGAAGAATGCTAAGTTTGTGTCCTTGCTCTGAAAATTGGTAAATCAAGCATGTTTG
  81 TTTACATTAAAAAGTCCAGACACACTGTATTGTGAAAACTGCTGAACATGTGGCAGCAATTTTGTGTTTTTATTTTGGAG
 161 ACGGCTAATGGTAGGAATGTTAATGTAAATAGTGGTGGTAATGTAAAATCATTTCATTTATCATTCATGCAAAAAAAAGT
 241 ATGTATTGAGTGCCTATTCATTGTCACTGTAGATGCAAAACGAATGAGCTGTAACCCCTTCACTCAAGGCATTGACAGCT
 321 TAGCTGTGAGGGTGGACACACATATGTGTATTTACAGTGCAGTGTAAATAGTTCTGTAGTAGAGGTTAACTCCATATTTC
 401 TGTGAGGTCACTGAGGCCTTATGGACTAACTCTGTGAGGATAGGAGTTATATATTCTTATAAGACAAAACAAAACAGGAC
 481 AATGTTACAAGAGTAAGAGGTTCTTACTTGTACATAGGCTTTCCTGCTGAAAACAGGCCCCTGCTGTACAGATTTTGGGT
 561 ACATAATTTAGCTCTTTTAGTCAATCCAAGAGATTTAAGTGACCCCCCCCCCCCCGTGTTTTTTTTGTTTTTGTTTTTGT
 641 TTTGAATGCCATGTAAAGGCTTTTTGGTTAAGACCTCACTTTTAAAACTGCCTTAAGTATAAATAGTACCTTTGGAATAT
 721 ATTTAGTTCATCATTTGAGCTGCCTTCATACTGGTTTCCTCAGCCTTCCTTCAGCCTGTAATATTTTCAGCCCACTGTTT
 801 ACCTTGTCTCAATAAAAGGTTTCTAATGCCAAATACGTACCTTTAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccGUUUUUG----GCGUUAAUGAAAa 5'
            ||: ||:    :|:  |||:||| 
Target 5' ggCAGCAATTTTGTGTTTTTATTTTg 3'
 132 - 157 130.00 -7.90
2 
miRNA  3' ccGUUUUUGGCGUUAAUGAAaa 5'
            :||:|:  |:  ||||||  
Target 5' agTAAGAG--GTTCTTACTTgt 3'
 492 - 511 128.00 -6.10
3 
miRNA  3' ccguUUUUGGCGUUAAUGAAAa 5'
              ||:|||    | ||||| 
Target 5' ggttAAGACC----TCACTTTt 3'
 666 - 683 120.00 -8.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM9084040 8 COSMIC
COSM8867387 9 COSMIC
COSN30457413 47 COSMIC
COSN30517504 53 COSMIC
COSN30493356 84 COSMIC
COSN30135391 100 COSMIC
COSN31559370 117 COSMIC
COSN31611464 127 COSMIC
COSN30492830 129 COSMIC
COSN31962290 141 COSMIC
COSN31611816 181 COSMIC
COSN30136128 199 COSMIC
COSN28017476 231 COSMIC
COSN30527262 244 COSMIC
COSN25176351 353 COSMIC
COSN24300528 481 COSMIC
COSN31608599 491 COSMIC
COSN31548634 566 COSMIC
COSN26465367 627 COSMIC
COSN31537482 634 COSMIC
COSN6581823 697 COSMIC
COSN26665188 741 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs372196702 4 dbSNP
rs758738214 9 dbSNP
rs534578726 19 dbSNP
rs755565714 22 dbSNP
rs754313844 35 dbSNP
rs766442852 36 dbSNP
rs756285326 38 dbSNP
rs567174662 46 dbSNP
rs767894050 47 dbSNP
rs1047653913 49 dbSNP
rs184602971 50 dbSNP
rs775416881 52 dbSNP
rs764958072 53 dbSNP
rs537130432 57 dbSNP
rs972403572 60 dbSNP
rs776461257 61 dbSNP
rs1447376569 64 dbSNP
rs770422154 65 dbSNP
rs369113207 69 dbSNP
rs1321660622 71 dbSNP
rs1370579064 76 dbSNP
rs1015169699 98 dbSNP
rs1186120189 105 dbSNP
rs1305837115 108 dbSNP
rs1339839966 134 dbSNP
rs1226333946 136 dbSNP
rs1039897548 162 dbSNP
rs144188302 163 dbSNP
rs914885100 187 dbSNP
rs1266019421 191 dbSNP
rs989118076 194 dbSNP
rs1202303520 196 dbSNP
rs1195138481 204 dbSNP
rs1245778596 211 dbSNP
rs887991277 217 dbSNP
rs956645826 224 dbSNP
rs181866177 226 dbSNP
rs533166461 227 dbSNP
rs970622694 231 dbSNP
rs907311732 238 dbSNP
rs1023481831 239 dbSNP
rs1393857509 239 dbSNP
rs990696817 241 dbSNP
rs1289939326 242 dbSNP
rs1412666929 244 dbSNP
rs750765863 245 dbSNP
rs1339565906 247 dbSNP
rs963310525 249 dbSNP
rs1296023484 251 dbSNP
rs1016919113 256 dbSNP
rs1334397315 256 dbSNP
rs565926457 259 dbSNP
rs1005581888 260 dbSNP
rs1046211934 281 dbSNP
rs1397275730 282 dbSNP
rs946067546 284 dbSNP
rs1382071334 288 dbSNP
rs547396759 291 dbSNP
rs373324313 296 dbSNP
rs1458195418 308 dbSNP
rs867493458 311 dbSNP
rs1414799669 314 dbSNP
rs1054425852 316 dbSNP
rs28760388 319 dbSNP
rs998684202 322 dbSNP
rs9993585 323 dbSNP
rs781560798 329 dbSNP
rs114909003 330 dbSNP
rs985325111 334 dbSNP
rs1039866196 340 dbSNP
rs1417685610 341 dbSNP
rs933805982 342 dbSNP
rs922401660 345 dbSNP
rs1472664285 346 dbSNP
rs1453285077 347 dbSNP
rs1289281989 348 dbSNP
rs369016050 350 dbSNP
rs894089736 362 dbSNP
rs1292606495 366 dbSNP
rs1189795234 371 dbSNP
rs1355953407 373 dbSNP
rs1445362480 374 dbSNP
rs1053845385 391 dbSNP
rs972455501 394 dbSNP
rs1316015038 398 dbSNP
rs1216088992 402 dbSNP
rs1262081336 413 dbSNP
rs1487055579 414 dbSNP
rs961077907 415 dbSNP
rs935051375 416 dbSNP
rs1016556247 417 dbSNP
rs1475818080 418 dbSNP
rs1190202078 421 dbSNP
rs1409823198 426 dbSNP
rs1418529303 429 dbSNP
rs532322132 434 dbSNP
rs1365690240 439 dbSNP
rs1329819923 441 dbSNP
rs1269919830 455 dbSNP
rs116439956 456 dbSNP
rs952341994 460 dbSNP
rs1376072960 463 dbSNP
rs1284440292 477 dbSNP
rs1034999218 479 dbSNP
rs1416516932 481 dbSNP
rs1306052682 482 dbSNP
rs1001732085 483 dbSNP
rs1223788522 484 dbSNP
rs1246475183 496 dbSNP
rs949120060 500 dbSNP
rs533820 503 dbSNP
rs1232642907 510 dbSNP
rs907360423 511 dbSNP
rs541113551 512 dbSNP
rs543450755 515 dbSNP
rs963280765 516 dbSNP
rs1480353372 518 dbSNP
rs1177799672 522 dbSNP
rs572395464 524 dbSNP
rs1452808984 535 dbSNP
rs891848220 537 dbSNP
rs1016226464 539 dbSNP
rs984518003 543 dbSNP
rs1054481342 546 dbSNP
rs1324460595 559 dbSNP
rs951378155 565 dbSNP
rs1442374892 570 dbSNP
rs1000170419 572 dbSNP
rs1414899442 574 dbSNP
rs1185013514 578 dbSNP
rs1165242214 583 dbSNP
rs1439678273 588 dbSNP
rs975166513 590 dbSNP
rs1303626460 592 dbSNP
rs998253355 595 dbSNP
rs1236867161 599 dbSNP
rs34784211 602 dbSNP
rs377027882 603 dbSNP
rs1467151659 604 dbSNP
rs747296509 604 dbSNP
rs1455430814 605 dbSNP
rs531686774 605 dbSNP
rs1410434643 606 dbSNP
rs1191461157 608 dbSNP
rs1466306615 610 dbSNP
rs1007041525 611 dbSNP
rs1372651114 611 dbSNP
rs1215686041 613 dbSNP
rs1361920951 613 dbSNP
rs1275668186 614 dbSNP
rs1219212985 615 dbSNP
rs1188242171 616 dbSNP
rs1274103173 616 dbSNP
rs140415777 616 dbSNP
rs1479042335 616 dbSNP
rs35619548 616 dbSNP
rs61039777 616 dbSNP
rs762417083 616 dbSNP
rs768279226 616 dbSNP
rs796762679 616 dbSNP
rs1450845357 617 dbSNP
rs894053580 621 dbSNP
rs1054081733 627 dbSNP
rs1345000898 627 dbSNP
rs777712136 627 dbSNP
rs1339698359 628 dbSNP
rs879091382 633 dbSNP
rs878915609 639 dbSNP
rs1293950619 643 dbSNP
rs1228582477 644 dbSNP
rs1337287414 644 dbSNP
rs369884689 650 dbSNP
rs889739344 652 dbSNP
rs751953625 653 dbSNP
rs1217616598 658 dbSNP
rs1255377403 659 dbSNP
rs694752 672 dbSNP
rs933879960 675 dbSNP
rs1188125589 677 dbSNP
rs1419368128 691 dbSNP
rs1436323867 698 dbSNP
rs922421038 702 dbSNP
rs1036784925 719 dbSNP
rs7154 720 dbSNP
rs1401704091 721 dbSNP
rs749249024 729 dbSNP
rs949090683 729 dbSNP
rs763408682 730 dbSNP
rs750832251 735 dbSNP
rs983778034 741 dbSNP
rs1169391795 748 dbSNP
rs1313959124 749 dbSNP
rs765785034 750 dbSNP
rs959276995 754 dbSNP
rs1279210771 765 dbSNP
rs1351643063 774 dbSNP
rs1225292940 777 dbSNP
rs190553448 781 dbSNP
rs916355492 791 dbSNP
rs990636243 792 dbSNP
rs941884610 804 dbSNP
rs773336631 807 dbSNP
rs769846874 808 dbSNP
rs1477678528 812 dbSNP
rs1435596348 814 dbSNP
rs1180441136 818 dbSNP
rs542943660 829 dbSNP
rs980751522 834 dbSNP
rs1470957149 835 dbSNP
rs573952761 836 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124A_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + A ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_124A_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + A
Location of target site ENST00000356260.5 | 3UTR | AUGAGAUUUUUUAAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
184 hsa-miR-548am-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057132 DDIT4 DNA damage inducible transcript 4 2 4
MIRT063379 ETNK1 ethanolamine kinase 1 2 2
MIRT072501 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT082193 ACTN4 actinin alpha 4 2 6
MIRT083043 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT085196 SLC5A3 solute carrier family 5 member 3 2 4
MIRT088913 FOXN2 forkhead box N2 2 4
MIRT089506 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 6
MIRT092047 ABHD5 abhydrolase domain containing 5 2 2
MIRT094692 FEM1C fem-1 homolog C 2 2
MIRT095403 UBE2D2 ubiquitin conjugating enzyme E2 D2 2 2
MIRT096509 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT101303 FAM135A family with sequence similarity 135 member A 2 2
MIRT103366 CBX3 chromobox 3 2 2
MIRT103883 FOXK1 forkhead box K1 2 2
MIRT104343 CLDN12 claudin 12 2 2
MIRT104508 PEG10 paternally expressed 10 2 6
MIRT111808 MPZL1 myelin protein zero like 1 2 2
MIRT177246 BMI1 BMI1 proto-oncogene, polycomb ring finger 2 2
MIRT177281 COMMD3-BMI1 COMMD3-BMI1 readthrough 2 2
MIRT177633 UBE2D1 ubiquitin conjugating enzyme E2 D1 2 6
MIRT178049 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT179109 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT179594 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 6
MIRT195307 LEPROT leptin receptor overlapping transcript 2 2
MIRT203152 BACH1 BTB domain and CNC homolog 1 2 2
MIRT208437 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT214585 SMAD5 SMAD family member 5 2 4
MIRT216112 IL6ST interleukin 6 signal transducer 2 2
MIRT216363 CCNB1 cyclin B1 2 4
MIRT220059 MDFIC MyoD family inhibitor domain containing 2 2
MIRT226737 ANP32B acidic nuclear phosphoprotein 32 family member B 2 4
MIRT227706 TBC1D13 TBC1 domain family member 13 2 2
MIRT230079 SH3BGRL SH3 domain binding glutamate rich protein like 2 2
MIRT248644 HMGN2 high mobility group nucleosomal binding domain 2 2 4
MIRT254799 XRCC6 X-ray repair cross complementing 6 2 6
MIRT264388 YAP1 Yes associated protein 1 2 2
MIRT266982 LRRC55 leucine rich repeat containing 55 2 4
MIRT273957 SPRYD4 SPRY domain containing 4 2 2
MIRT281809 MAP2K1 mitogen-activated protein kinase kinase 1 2 2
MIRT293262 DR1 down-regulator of transcription 1 2 2
MIRT297105 RGPD4 RANBP2-like and GRIP domain containing 4 2 2
MIRT308178 PDE12 phosphodiesterase 12 2 2
MIRT309022 USP53 ubiquitin specific peptidase 53 2 2
MIRT311477 PRRC1 proline rich coiled-coil 1 2 2
MIRT312595 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT328137 ZNF711 zinc finger protein 711 2 2
MIRT329321 FAM53C family with sequence similarity 53 member C 2 2
MIRT334649 NEK7 NIMA related kinase 7 2 2
MIRT340680 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT378865 ITGB8 integrin subunit beta 8 2 2
MIRT395798 SPCS3 signal peptidase complex subunit 3 2 2
MIRT405648 WBP4 WW domain binding protein 4 2 4
MIRT408294 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT442112 ZNRF2 zinc and ring finger 2 2 8
MIRT442855 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT443131 VLDLR very low density lipoprotein receptor 2 2
MIRT443162 ZDHHC21 zinc finger DHHC-type containing 21 2 2
MIRT443313 PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 2 2
MIRT445095 ZNF207 zinc finger protein 207 2 2
MIRT445399 PTCHD1 patched domain containing 1 2 4
MIRT447085 MCC mutated in colorectal cancers 2 2
MIRT447315 ZNF562 zinc finger protein 562 2 2
MIRT447528 MRPS5 mitochondrial ribosomal protein S5 2 2
MIRT449526 TM6SF1 transmembrane 6 superfamily member 1 2 2
MIRT449917 C11orf34 placenta expressed transcript 1 1 2
MIRT450566 SHFM1 SEM1, 26S proteasome complex subunit 2 2
MIRT450734 PVRL3 nectin cell adhesion molecule 3 2 2
MIRT454938 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 12
MIRT455907 KIF2C kinesin family member 2C 2 2
MIRT463747 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 2 8
MIRT471197 PHB2 prohibitin 2 2 2
MIRT472779 MTMR6 myotubularin related protein 6 2 8
MIRT474472 KLHL11 kelch like family member 11 2 8
MIRT476000 GTPBP2 GTP binding protein 2 2 2
MIRT482291 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT485873 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT486207 ERH ERH, mRNA splicing and mitosis factor 2 4
MIRT488624 FAM3C family with sequence similarity 3 member C 2 6
MIRT489999 DDB1 damage specific DNA binding protein 1 2 2
MIRT493491 IPMK inositol polyphosphate multikinase 2 2
MIRT494295 CEP120 centrosomal protein 120 2 2
MIRT498007 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT498488 PTBP2 polypyrimidine tract binding protein 2 2 10
MIRT498575 TMEM30B transmembrane protein 30B 2 2
MIRT499882 SVOP SV2 related protein 2 10
MIRT500235 INHBA inhibin beta A subunit 2 10
MIRT500709 TRIM37 tripartite motif containing 37 2 2
MIRT501003 SPPL2A signal peptide peptidase like 2A 2 4
MIRT501038 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502751 CLIP1 CAP-Gly domain containing linker protein 1 2 8
MIRT502813 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 6
MIRT502903 CDK4 cyclin dependent kinase 4 2 8
MIRT503498 ZNF154 zinc finger protein 154 2 6
MIRT503732 GRM5 glutamate metabotropic receptor 5 2 2
MIRT505152 YOD1 YOD1 deubiquitinase 2 2
MIRT505817 RSBN1 round spermatid basic protein 1 2 8
MIRT505856 POLR1B RNA polymerase I subunit B 2 4
MIRT509299 NPM3 nucleophosmin/nucleoplasmin 3 2 6
MIRT516844 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT520534 TRA2B transformer 2 beta homolog 2 2
MIRT520738 TM9SF3 transmembrane 9 superfamily member 3 2 6
MIRT525418 SHISA9 shisa family member 9 2 4
MIRT525882 ARL13B ADP ribosylation factor like GTPase 13B 2 2
MIRT526028 RBM4B RNA binding motif protein 4B 2 2
MIRT526099 TMEM41B transmembrane protein 41B 2 2
MIRT527946 FRY FRY microtubule binding protein 2 2
MIRT528833 RAB32 RAB32, member RAS oncogene family 2 2
MIRT531077 SLC9A4 solute carrier family 9 member A4 2 4
MIRT535510 PANX1 pannexin 1 2 2
MIRT536697 IKZF5 IKAROS family zinc finger 5 2 2
MIRT536850 HMBOX1 homeobox containing 1 2 2
MIRT537217 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT537849 EFNA5 ephrin A5 2 2
MIRT538360 CSE1L chromosome segregation 1 like 2 4
MIRT541257 GPC4 glypican 4 2 2
MIRT543250 PEX7 peroxisomal biogenesis factor 7 2 2
MIRT543465 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT543726 XKR9 XK related 9 2 2
MIRT543922 ESYT1 extended synaptotagmin 1 2 2
MIRT544014 KLRC3 killer cell lectin like receptor C3 2 2
MIRT544085 METTL8 methyltransferase like 8 2 2
MIRT544202 ANGPTL3 angiopoietin like 3 2 2
MIRT544823 ACSM2B acyl-CoA synthetase medium chain family member 2B 2 2
MIRT545061 PRELID1 PRELI domain containing 1 2 2
MIRT545229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT545304 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT545565 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT546512 SIK1 salt inducible kinase 1 2 2
MIRT546929 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT547690 KPNA1 karyopherin subunit alpha 1 2 4
MIRT547783 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT548702 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT548916 CHEK2 checkpoint kinase 2 2 4
MIRT549972 RPL7L1 ribosomal protein L7 like 1 2 4
MIRT550504 TMEM241 transmembrane protein 241 2 2
MIRT551064 MKLN1 muskelin 1 2 2
MIRT552826 XIAP X-linked inhibitor of apoptosis 2 4
MIRT553160 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT553845 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT554273 SIX4 SIX homeobox 4 2 2
MIRT555796 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 2
MIRT556333 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556514 LIPA lipase A, lysosomal acid type 2 2
MIRT556708 KLHL28 kelch like family member 28 2 2
MIRT556767 KLF7 Kruppel like factor 7 2 2
MIRT557005 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557161 HOXA13 homeobox A13 2 2
MIRT557502 GPR27 G protein-coupled receptor 27 2 4
MIRT558117 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT559359 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT560350 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT561314 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT561898 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT561942 MFSD9 major facilitator superfamily domain containing 9 2 2
MIRT562950 TNIP2 TNFAIP3 interacting protein 2 2 2
MIRT563306 BBS10 Bardet-Biedl syndrome 10 2 2
MIRT563420 KIF3A kinesin family member 3A 2 2
MIRT563577 KIAA1586 KIAA1586 2 2
MIRT565891 NHS NHS actin remodeling regulator 2 2
MIRT566096 RCC2 regulator of chromosome condensation 2 2 2
MIRT566411 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT567274 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT571483 CCDC80 coiled-coil domain containing 80 2 2
MIRT572954 VDAC2 voltage dependent anion channel 2 2 2
MIRT573643 ZNF724P zinc finger protein 724 2 2
MIRT573732 KHSRP KH-type splicing regulatory protein 2 2
MIRT609103 SMIM15 small integral membrane protein 15 2 6
MIRT617951 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT618394 PRKG2 protein kinase, cGMP-dependent, type II 2 2
MIRT619642 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 2
MIRT623470 KDM5A lysine demethylase 5A 2 2
MIRT629160 CTCFL CCCTC-binding factor like 2 2
MIRT638536 LYRM2 LYR motif containing 2 2 2
MIRT649498 CLDN16 claudin 16 2 2
MIRT683163 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 2
MIRT691675 SLC43A3 solute carrier family 43 member 3 2 2
MIRT693216 MKI67 marker of proliferation Ki-67 2 2
MIRT695349 AQP3 aquaporin 3 (Gill blood group) 2 2
MIRT701038 PCGF5 polycomb group ring finger 5 2 2
MIRT708768 RYBP RING1 and YY1 binding protein 2 2
MIRT717573 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT719301 SETD7 SET domain containing lysine methyltransferase 7 2 2
MIRT725187 SDAD1 SDA1 domain containing 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-548am-5p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-548am-5p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-548am-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-548am-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

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