miRTarBase - #MIRT725523


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pre-miRNA Information
pre-miRNA hsa-mir-500b   
Genomic Coordinates chrX: 50010672 - 50010750
Description Homo sapiens miR-500b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-500b-3p
Sequence 51| GCACCCAGGCAAGGAUUCUG |70
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs782140253 8 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol FAM229B   
Synonyms C6orf225
Description family with sequence similarity 229 member B
Transcript NM_001033564   
Expression
Putative miRNA Targets on FAM229B
3'UTR of FAM229B
(miRNA target sites are highlighted)		 
>FAM229B|NM_001033564|3'UTR
   1 CACCATTAAGTCTTTTGTCAAGGTCTGACTAGGTCAAGGGTAATGGACCAGTATCATCTGGTGATCTGGTAAACAAATAA
  81 AAGTGGTGGCACCTTTAGATGATGACAACAGTTGAGCTCTTTACTTTTAGTAAGACCGACAGAAATGTAGTCAGTAAAGC
 161 ACATGTAGTGATAGGCTATCAGTTATGTCTGATACATAAGACAGAATAATATTTCACAATTAGAAAGTACCTTAGAGATC
 241 ATCTTGCTCACAGTAGATCATTAATATCAATAATTAAAGATGAAGCTTAATCCACCATGGTCATCAGTCAGGTGGGGCTT
 321 ATTCTAAATGCTTAATGTGTCTTAAGCTCATTTCCTTGTTCATATTTGGGTTGCTACTTGGCTAAATCCTTTCACCTTAG
 401 TACCCTAAGCCAGTTTCCTGGCTTGATACTATTTGATAATGCTCTGCTCAGGAATGATTATATTGGGTGAGAAATGGAGC
 481 CCTGGGGTTGTGTGTTTTGGAACAGTATTCAAGATCAAAGAAAGTTCTTAGTCCATGGTTAATCTGCAAGGCATTTAAGC
 561 CACTTCCATAGAGGAGCCCAGATTGTTGGTTAAATATATTGATAATGAAGTCAAAGCTGTGGTTCCAACCCCGATTTTTC
 641 CAAGAAAAATGACGTCTGGTTATCACTTTGTACACGAAGTGCTAACCAGGTATCTTGATAAATTGTTTACAGTAGGTATT
 721 GAGAAACCTCATGTGGATTTTTTAATTTGGTTAGATGTGGGATCACTTTTGAGGATGAGGCCAGCTCTCTATGTTCTCTT
 801 TTTCTTCTTGCAGTAGTCCCCAGAAACTCAGTCTGCTTTCCTTTTCTCTCGATGGCTGTCAGCACCCATCTAATGAAATT
 881 GTCTTCTCCAAAAGACTGACTTTAGGATCAGATACAATTTTCACCAGTGTTTTTTGTCTACCTTGCTGCTTCTGAAAATA
 961 TACATATAAGCCTTTTAAAATGAAAAGTTTATTAACTTATAATTAAATAGACGTAGATGCATATGTGTTGCATTAGGTGA
1041 AAAGAAAAACTGCCAGGGAGTTATAAGAGGAAAAACTCTCAGAGCTCACACTGAGCTGGGAGAAGTTTGAATGCCAACCA
1121 GTTAAAGTGGAAAGATCTTGAACATGTGGGGCATTGAGTAGAGACTCAGAAAGGTTGTACTTTCATAAGAGATCCAAACT
1201 GGAGCTAGACTAAAGGCTAATGTATACCAATTTTAAGAAAGCTTAAAAATAAGCCTTGAGAGACTCAAGATGATCTCTAA
1281 GTAACCTCATTTTATCTGCCAAATAAAAATAGAACATTCCTTAAAGGAAGAAAACAAAATCGAGGCAGGAAATTGCCTGA
1361 GGCTGGAGAAAAAATGACAGGAAGGAGAAAGGAGTGATGAAAAATTCCTCAGAGGGCTGGGCTTGGTGGCTCATGCCTGT
1441 AATCCTGGCACTTTGGGAGGCCGAAGTGGATGGATTATCTGAGGTCAGGCATTCGAAGCCAGCCTGGCCAACATGGTGAA
1521 ACCCCGACTCTACTAAAAATACAAAAATTAGTCGGGTATGATGGGCAGGTGCCTGTAATTCCAGCTACTTGGGAGGCTGA
1601 GGCAGGAAAATAGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCATCACTGTGCTCCAGCCTAGGCAACA
1681 GAGTGAGACTTTGTCTCAAAAAAAAAGAAAAACAAAGAAAAATTCCTCAGAGCTCATACAAGGCTGGGTAGAATATGTGT
1761 TTCAACAATAGTGGATCTTTTAATATAGTACATGGATCATTGAGTAGAGTCTTCAGCAAAATATTGGCAAAGTAGGGTTA
1841 GGGTTAGGTTAGGGAGATGGGAATAGACTGAAGACTACTCTGGACTTGCCCTAACAGAGTTTAAGAGCAACATTTGAAAG
1921 GATCAAACTGATTTCAAGTAACTTGAGTGCATCCAAGGGGAGAAAACCCATCAAAATAAAAATAAAAACTACAATAAAAT
2001 CCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guCUUAGGAACG-GACCCACg 5'
            ||||  || : :|||||| 
Target 5' agGAATGATTATATTGGGTGa 3'
 450 - 470 138.00 -13.80
2 
miRNA  3' gucuUAGGAACGGACCCAcg 5'
              || |  | ||||||  
Target 5' gctcATACAAGGCTGGGTag 3'
 1732 - 1751 128.00 -10.70
3 
miRNA  3' guCUUAGGAACGGACCCACg 5'
            ||:  || | || |||| 
Target 5' caGAGGGCTGGGCTTGGTGg 3'
 1410 - 1429 122.00 -15.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM5357284 1 COSMIC
COSN27677683 4 COSMIC
COSN30491874 5 COSMIC
COSN30480842 13 COSMIC
COSN30507336 17 COSMIC
COSN23627575 20 COSMIC
COSN30125491 26 COSMIC
COSN30502205 29 COSMIC
COSN31509173 54 COSMIC
COSN31479653 64 COSMIC
COSN30140814 102 COSMIC
COSN30105973 109 COSMIC
COSN30482427 120 COSMIC
COSN20335947 165 COSMIC
COSN30201018 247 COSMIC
COSN15662534 668 COSMIC
COSN7594073 762 COSMIC
COSN28429446 937 COSMIC
COSN24962766 1014 COSMIC
COSN15660628 1141 COSMIC
COSN24602246 1477 COSMIC
COSN17650192 1820 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781812206 2 dbSNP
rs1311236991 13 dbSNP
rs1393700099 13 dbSNP
rs1397266039 19 dbSNP
rs1330848205 24 dbSNP
rs782440866 28 dbSNP
rs183512768 38 dbSNP
rs931546665 40 dbSNP
rs782252871 41 dbSNP
rs782488915 43 dbSNP
rs782683053 45 dbSNP
rs782281193 46 dbSNP
rs782186129 53 dbSNP
rs1367725061 57 dbSNP
rs887101184 60 dbSNP
rs938624177 64 dbSNP
rs1057244176 67 dbSNP
rs1185288687 71 dbSNP
rs894522219 72 dbSNP
rs782771132 80 dbSNP
rs1250597628 84 dbSNP
rs1197471147 87 dbSNP
rs1456124824 90 dbSNP
rs3177143 92 dbSNP
rs1045282900 100 dbSNP
rs1214654066 103 dbSNP
rs587773083 110 dbSNP
rs77668306 115 dbSNP
rs781965360 117 dbSNP
rs1241802053 132 dbSNP
rs587727519 138 dbSNP
rs1000735222 144 dbSNP
rs1030836723 161 dbSNP
rs17073353 165 dbSNP
rs1373424232 169 dbSNP
rs782533131 171 dbSNP
rs1326797876 182 dbSNP
rs1405025656 183 dbSNP
rs1389740936 188 dbSNP
rs782540935 190 dbSNP
rs187945530 194 dbSNP
rs117944757 195 dbSNP
rs1177424561 197 dbSNP
rs975638488 207 dbSNP
rs1254389402 208 dbSNP
rs587598947 215 dbSNP
rs1450751041 228 dbSNP
rs191979702 232 dbSNP
rs1207276749 241 dbSNP
rs952977143 246 dbSNP
rs1351948822 248 dbSNP
rs587730925 249 dbSNP
rs983032974 260 dbSNP
rs1238667844 298 dbSNP
rs1350099897 302 dbSNP
rs141711877 306 dbSNP
rs1436007763 315 dbSNP
rs1329574711 320 dbSNP
rs782162769 322 dbSNP
rs1383737322 325 dbSNP
rs1361034663 326 dbSNP
rs1157953683 338 dbSNP
rs1417829981 341 dbSNP
rs1396359219 344 dbSNP
rs1172717259 348 dbSNP
rs587679415 351 dbSNP
rs1244629240 359 dbSNP
rs587734532 364 dbSNP
rs1262965268 369 dbSNP
rs782455417 370 dbSNP
rs112847005 373 dbSNP
rs754715779 384 dbSNP
rs1281053562 396 dbSNP
rs1218724026 397 dbSNP
rs185221569 401 dbSNP
rs1272166665 404 dbSNP
rs148470259 419 dbSNP
rs145358007 420 dbSNP
rs1297426522 421 dbSNP
rs1398056281 428 dbSNP
rs1377216644 430 dbSNP
rs1334172723 434 dbSNP
rs1422564689 438 dbSNP
rs147679083 440 dbSNP
rs782124735 442 dbSNP
rs1477979718 443 dbSNP
rs1423336923 449 dbSNP
rs1191967632 457 dbSNP
rs782593774 466 dbSNP
rs782495807 471 dbSNP
rs1486900803 477 dbSNP
rs188233236 482 dbSNP
rs1209448352 491 dbSNP
rs1440748375 494 dbSNP
rs903687590 495 dbSNP
rs1196598902 501 dbSNP
rs78129129 506 dbSNP
rs1052317577 524 dbSNP
rs892361714 536 dbSNP
rs1007874077 546 dbSNP
rs1357247274 547 dbSNP
rs1019687826 566 dbSNP
rs1447270992 569 dbSNP
rs1014479 579 dbSNP
rs996995990 586 dbSNP
rs1465762998 588 dbSNP
rs1399096882 597 dbSNP
rs184378840 607 dbSNP
rs1168928809 630 dbSNP
rs782227164 633 dbSNP
rs952863069 634 dbSNP
rs587703222 642 dbSNP
rs1472135044 653 dbSNP
rs782661534 654 dbSNP
rs982918123 655 dbSNP
rs1457432423 656 dbSNP
rs1256437529 657 dbSNP
rs2010315 658 dbSNP
rs1323266271 660 dbSNP
rs1290408351 661 dbSNP
rs142329763 665 dbSNP
rs1227656111 667 dbSNP
rs2010314 675 dbSNP
rs587597727 676 dbSNP
rs915889029 677 dbSNP
rs781927671 681 dbSNP
rs1446924409 682 dbSNP
rs587642816 695 dbSNP
rs1375632120 705 dbSNP
rs1328844104 714 dbSNP
rs1462726538 720 dbSNP
rs1350829391 726 dbSNP
rs1164588398 731 dbSNP
rs1404038126 738 dbSNP
rs1410809299 750 dbSNP
rs1179294531 752 dbSNP
rs1439191274 758 dbSNP
rs62416961 761 dbSNP
rs1236489214 777 dbSNP
rs5879136 781 dbSNP
rs1488960425 787 dbSNP
rs979263044 790 dbSNP
rs1220559432 791 dbSNP
rs1319811756 802 dbSNP
rs587722442 809 dbSNP
rs1240847403 811 dbSNP
rs1352293000 812 dbSNP
rs936527558 816 dbSNP
rs1306537867 818 dbSNP
rs73541464 827 dbSNP
rs1367885950 830 dbSNP
rs1293236642 832 dbSNP
rs892413453 842 dbSNP
rs1347416486 845 dbSNP
rs781890891 851 dbSNP
rs188293635 852 dbSNP
rs1378532365 870 dbSNP
rs374591346 870 dbSNP
rs782351252 872 dbSNP
rs1424759876 875 dbSNP
rs587730402 876 dbSNP
rs1487369420 880 dbSNP
rs1265114881 881 dbSNP
rs1217242183 891 dbSNP
rs1487955325 894 dbSNP
rs1283190910 895 dbSNP
rs1234790734 898 dbSNP
rs587611931 904 dbSNP
rs1300196414 908 dbSNP
rs1217171868 913 dbSNP
rs1342741148 915 dbSNP
rs180905776 924 dbSNP
rs1399868902 926 dbSNP
rs1359187550 929 dbSNP
rs1314781217 930 dbSNP
rs1027161116 939 dbSNP
rs1466635162 962 dbSNP
rs1377186983 963 dbSNP
rs888172612 974 dbSNP
rs1174179556 978 dbSNP
rs1430587835 982 dbSNP
rs1425490412 983 dbSNP
rs1194135797 985 dbSNP
rs1004407410 992 dbSNP
rs1260982562 1000 dbSNP
rs368709487 1005 dbSNP
rs146621216 1013 dbSNP
rs960312337 1014 dbSNP
rs1254948479 1019 dbSNP
rs993490465 1022 dbSNP
rs1023183347 1031 dbSNP
rs1319566426 1032 dbSNP
rs970477974 1035 dbSNP
rs1279161098 1037 dbSNP
rs184599888 1038 dbSNP
rs781975327 1039 dbSNP
rs1339025359 1056 dbSNP
rs926064464 1059 dbSNP
rs1315407167 1063 dbSNP
rs1397163751 1065 dbSNP
rs1301230331 1066 dbSNP
rs1467325636 1068 dbSNP
rs111596260 1078 dbSNP
rs987970785 1085 dbSNP
rs1171062704 1088 dbSNP
rs1464933928 1090 dbSNP
rs913736446 1093 dbSNP
rs943844583 1118 dbSNP
rs1189502588 1122 dbSNP
rs1424382990 1144 dbSNP
rs1254860391 1145 dbSNP
rs1041365489 1156 dbSNP
rs899718964 1157 dbSNP
rs1179625324 1161 dbSNP
rs1458783635 1163 dbSNP
rs932325112 1174 dbSNP
rs782780530 1175 dbSNP
rs888224956 1177 dbSNP
rs1316426350 1178 dbSNP
rs1267667553 1179 dbSNP
rs1246159957 1188 dbSNP
rs778554368 1198 dbSNP
rs1340403032 1200 dbSNP
rs1310590916 1204 dbSNP
rs1003957440 1210 dbSNP
rs587713323 1213 dbSNP
rs1015808906 1215 dbSNP
rs73541466 1217 dbSNP
rs1014396122 1218 dbSNP
rs1464306268 1226 dbSNP
rs1023658997 1227 dbSNP
rs1394047796 1228 dbSNP
rs1164845566 1239 dbSNP
rs1458299256 1246 dbSNP
rs1367846425 1256 dbSNP
rs1162050115 1259 dbSNP
rs6901156 1273 dbSNP
rs782647486 1282 dbSNP
rs371106576 1286 dbSNP
rs1456222092 1289 dbSNP
rs374315003 1293 dbSNP
rs1210822871 1296 dbSNP
rs1356203663 1303 dbSNP
rs782712788 1312 dbSNP
rs1242998295 1313 dbSNP
rs1354474331 1317 dbSNP
rs1308690206 1323 dbSNP
rs115929516 1326 dbSNP
rs1333048702 1327 dbSNP
rs988861272 1342 dbSNP
rs911940128 1352 dbSNP
rs1389800680 1369 dbSNP
rs1301195738 1389 dbSNP
rs1421503278 1392 dbSNP
rs1380372960 1400 dbSNP
rs587640378 1406 dbSNP
rs1157534731 1409 dbSNP
rs1468233424 1413 dbSNP
rs782005947 1414 dbSNP
rs781821402 1417 dbSNP
rs1451360284 1418 dbSNP
rs1265765046 1419 dbSNP
rs782638554 1421 dbSNP
rs1488939654 1422 dbSNP
rs1285309303 1423 dbSNP
rs782490164 1424 dbSNP
rs189333914 1426 dbSNP
rs1275633020 1434 dbSNP
rs932571929 1436 dbSNP
rs1330288429 1444 dbSNP
rs587766966 1454 dbSNP
rs782779290 1463 dbSNP
rs939634085 1464 dbSNP
rs1398481081 1469 dbSNP
rs782455590 1472 dbSNP
rs587642632 1484 dbSNP
rs1172776732 1489 dbSNP
rs1477524073 1494 dbSNP
rs181633539 1495 dbSNP
rs1196300107 1499 dbSNP
rs1478399648 1505 dbSNP
rs1263147101 1507 dbSNP
rs1214332658 1511 dbSNP
rs1014861307 1518 dbSNP
rs147893816 1526 dbSNP
rs1343145583 1527 dbSNP
rs1281077397 1530 dbSNP
rs1220263208 1531 dbSNP
rs1341007971 1548 dbSNP
rs1277451219 1554 dbSNP
rs1428608540 1559 dbSNP
rs906143317 1564 dbSNP
rs186935662 1570 dbSNP
rs1413482318 1572 dbSNP
rs1403451308 1586 dbSNP
rs1173228386 1587 dbSNP
rs6906094 1593 dbSNP
rs1423418553 1594 dbSNP
rs1474098649 1601 dbSNP
rs587608322 1605 dbSNP
rs1186951382 1626 dbSNP
rs1460111275 1628 dbSNP
rs1199549986 1638 dbSNP
rs1318306325 1662 dbSNP
rs1257250974 1663 dbSNP
rs1212728673 1672 dbSNP
rs1381255366 1673 dbSNP
rs1284211329 1686 dbSNP
rs1446675989 1691 dbSNP
rs1379996089 1695 dbSNP
rs11373481 1698 dbSNP
rs1332932058 1698 dbSNP
rs369984424 1698 dbSNP
rs1168782524 1704 dbSNP
rs200949375 1708 dbSNP
rs202240592 1709 dbSNP
rs1407521637 1710 dbSNP
rs191406717 1712 dbSNP
rs1162698731 1714 dbSNP
rs368885332 1718 dbSNP
rs1240157141 1722 dbSNP
rs1179478133 1735 dbSNP
rs1457535769 1735 dbSNP
rs587709856 1736 dbSNP
rs1019003128 1744 dbSNP
rs1202195067 1746 dbSNP
rs966134237 1753 dbSNP
rs1323377739 1759 dbSNP
rs977018198 1772 dbSNP
rs1290471480 1793 dbSNP
rs868970063 1799 dbSNP
rs1356628391 1805 dbSNP
rs781920733 1815 dbSNP
rs2213842 1821 dbSNP
rs1296762426 1825 dbSNP
rs1350872614 1833 dbSNP
rs1439090061 1833 dbSNP
rs954138158 1838 dbSNP
rs1423358859 1840 dbSNP
rs1382241261 1846 dbSNP
rs79763880 1854 dbSNP
rs1439252880 1858 dbSNP
rs909772237 1860 dbSNP
rs939686862 1861 dbSNP
rs1036681067 1875 dbSNP
rs1406085660 1877 dbSNP
rs1175221801 1879 dbSNP
rs1489329497 1880 dbSNP
rs1247131021 1887 dbSNP
rs1221652503 1889 dbSNP
rs1489841412 1891 dbSNP
rs1287469043 1893 dbSNP
rs1216735296 1894 dbSNP
rs1315919345 1901 dbSNP
rs776964335 1909 dbSNP
rs1304374653 1917 dbSNP
rs1220644813 1924 dbSNP
rs1368731904 1925 dbSNP
rs587751980 1928 dbSNP
rs1274698062 1941 dbSNP
rs1403566440 1943 dbSNP
rs1363016716 1944 dbSNP
rs1298830732 1945 dbSNP
rs1419204516 1949 dbSNP
rs2213843 1955 dbSNP
rs1434052631 1968 dbSNP
rs1425527700 1971 dbSNP
rs1198439443 1973 dbSNP
rs1479388962 1979 dbSNP
rs587657493 1984 dbSNP
rs949822974 1989 dbSNP
rs1258494966 1992 dbSNP
rs1211791347 1997 dbSNP
rs1312413402 1998 dbSNP
rs1262843941 2004 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124A_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + A ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gucuuaggaacgGACCCACg 5'
                      :|||||| 
Target 5' -----------aUUGGGUGa 3'
 		1 - 9
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
CLIP-seq Support 1 for dataset Chi_124A_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + A
Location of target site ENST00000368656.2 | 3UTR | AUUGGGUGAGAAAUGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
172 hsa-miR-500b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059905 HDGF heparin binding growth factor 2 4
MIRT235394 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 4
MIRT442246 PYGO1 pygopus family PHD finger 1 2 2
MIRT443591 ZNF439 zinc finger protein 439 2 4
MIRT453280 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT463540 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT465589 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT469462 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT485449 KCTD15 potassium channel tetramerization domain containing 15 2 4
MIRT486682 WDR81 WD repeat domain 81 2 2
MIRT489078 POLM DNA polymerase mu 2 2
MIRT493734 GREM2 gremlin 2, DAN family BMP antagonist 2 2
MIRT494872 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT496130 RNF103-CHMP3 RNF103-CHMP3 readthrough 2 2
MIRT496489 CHMP3 charged multivesicular body protein 3 2 2
MIRT496924 CLMN calmin 2 2
MIRT497297 TMEM119 transmembrane protein 119 2 2
MIRT499103 AGRN agrin 2 2
MIRT508979 CXorf38 chromosome X open reading frame 38 2 2
MIRT509911 NIPAL1 NIPA like domain containing 1 2 2
MIRT512820 ARRDC2 arrestin domain containing 2 2 4
MIRT512827 KBTBD6 kelch repeat and BTB domain containing 6 2 4
MIRT515360 MRPL52 mitochondrial ribosomal protein L52 2 2
MIRT516610 TRIM58 tripartite motif containing 58 2 2
MIRT517053 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT517637 ZNF491 zinc finger protein 491 2 2
MIRT518270 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT518625 STAR steroidogenic acute regulatory protein 2 2
MIRT518887 N4BP2L2 NEDD4 binding protein 2 like 2 2 2
MIRT519026 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT520365 UBE2G2 ubiquitin conjugating enzyme E2 G2 2 2
MIRT521106 SLC1A5 solute carrier family 1 member 5 2 2
MIRT521943 PHC3 polyhomeotic homolog 3 2 2
MIRT522253 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT522853 KIAA1551 KIAA1551 2 2
MIRT522868 KIAA1549 KIAA1549 2 2
MIRT524207 DDX19B DEAD-box helicase 19B 2 2
MIRT526004 ARHGAP27 Rho GTPase activating protein 27 2 2
MIRT527769 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT527827 TMEM74B transmembrane protein 74B 2 2
MIRT527861 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT528040 WT1 Wilms tumor 1 2 2
MIRT529802 ZDHHC8 zinc finger DHHC-type containing 8 2 2
MIRT531723 TARS threonyl-tRNA synthetase 2 2
MIRT531996 BARD1 BRCA1 associated RING domain 1 2 2
MIRT533338 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT533621 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT533652 TMOD2 tropomodulin 2 2 2
MIRT534397 SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2 2
MIRT538686 CCDC80 coiled-coil domain containing 80 2 2
MIRT540444 RBM43 RNA binding motif protein 43 2 2
MIRT542586 ZC3H12C zinc finger CCCH-type containing 12C 2 8
MIRT542796 PLEKHA3 pleckstrin homology domain containing A3 2 4
MIRT542991 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT544424 ZNF460 zinc finger protein 460 2 4
MIRT545740 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 2 4
MIRT552618 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT554456 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT569663 PRIM1 DNA primase subunit 1 2 2
MIRT569924 PCSK9 proprotein convertase subtilisin/kexin type 9 2 2
MIRT570140 IL1RL2 interleukin 1 receptor like 2 2 2
MIRT573558 TMEM120B transmembrane protein 120B 2 2
MIRT574282 OPRD1 opioid receptor delta 1 2 2
MIRT575335 Fbxo6 F-box protein 6 2 2
MIRT607057 IDS iduronate 2-sulfatase 2 2
MIRT607078 POM121L7 POM121 transmembrane nucleoporin like 7 pseudogene 2 2
MIRT607500 HEBP2 heme binding protein 2 2 2
MIRT607530 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT607808 RHBDL2 rhomboid like 2 2 2
MIRT608079 ZFP14 ZFP14 zinc finger protein 2 2
MIRT609119 NUDT3 nudix hydrolase 3 2 2
MIRT609745 PTCH1 patched 1 2 2
MIRT612904 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 2 2
MIRT618720 PCSK2 proprotein convertase subtilisin/kexin type 2 2 2
MIRT618778 HLA-E major histocompatibility complex, class I, E 2 2
MIRT619015 SLC2A6 solute carrier family 2 member 6 2 2
MIRT623223 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT623819 GEMIN6 gem nuclear organelle associated protein 6 2 2
MIRT625704 OPTN optineurin 2 2
MIRT626437 CHDH choline dehydrogenase 2 2
MIRT628087 KAT7 lysine acetyltransferase 7 2 2
MIRT628936 APOB apolipoprotein B 2 2
MIRT633543 PGBD5 piggyBac transposable element derived 5 2 2
MIRT634348 SGOL1 shugoshin 1 2 2
MIRT634611 KIAA1919 major facilitator superfamily domain containing 4B 2 2
MIRT635243 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT636681 BTLA B and T lymphocyte associated 2 2
MIRT636923 ZNF845 zinc finger protein 845 2 2
MIRT637606 ZNF554 zinc finger protein 554 2 2
MIRT639242 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT640835 POLR3A RNA polymerase III subunit A 2 2
MIRT642098 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT643087 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT643934 C17orf104 meiosis specific with coiled-coil domain 2 2
MIRT644353 FXN frataxin 2 2
MIRT645628 SF3A3 splicing factor 3a subunit 3 2 2
MIRT645754 FAM213A family with sequence similarity 213 member A 2 2
MIRT646329 MVB12B multivesicular body subunit 12B 2 2
MIRT646817 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT647019 ADCY2 adenylate cyclase 2 2 2
MIRT647621 IGSF9B immunoglobulin superfamily member 9B 2 2
MIRT648517 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT648871 ABCA6 ATP binding cassette subfamily A member 6 2 2
MIRT649620 ITPKC inositol-trisphosphate 3-kinase C 2 2
MIRT650062 CCDC134 coiled-coil domain containing 134 2 2
MIRT650734 TNFSF8 TNF superfamily member 8 2 2
MIRT652389 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT654352 RBM27 RNA binding motif protein 27 2 2
MIRT655796 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT657329 HNRNPK heterogeneous nuclear ribonucleoprotein K 2 2
MIRT657734 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT660613 ANO6 anoctamin 6 2 2
MIRT661243 ARL17B ADP ribosylation factor like GTPase 17B 2 2
MIRT662245 PGBD4 piggyBac transposable element derived 4 2 2
MIRT662921 MED18 mediator complex subunit 18 2 2
MIRT662963 JPH2 junctophilin 2 2 2
MIRT663347 ZNF74 zinc finger protein 74 2 2
MIRT663528 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT663547 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663977 ZNF786 zinc finger protein 786 2 2
MIRT664084 METTL2B methyltransferase like 2B 2 2
MIRT664358 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT664421 TIGD6 tigger transposable element derived 6 2 2
MIRT664476 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT664979 TDRD1 tudor domain containing 1 2 2
MIRT665128 PYCRL pyrroline-5-carboxylate reductase 3 2 2
MIRT666259 SLC31A1 solute carrier family 31 member 1 2 2
MIRT666321 SLC16A10 solute carrier family 16 member 10 2 2
MIRT666881 POLQ DNA polymerase theta 2 2
MIRT668469 FADS6 fatty acid desaturase 6 2 2
MIRT669554 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT669835 ISCA2 iron-sulfur cluster assembly 2 2 2
MIRT670185 CCDC142 coiled-coil domain containing 142 2 2
MIRT672020 PXMP4 peroxisomal membrane protein 4 2 2
MIRT672070 KIAA0930 KIAA0930 2 2
MIRT672475 RTTN rotatin 2 2
MIRT672851 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT673090 AK1 adenylate kinase 1 2 2
MIRT673581 KDELC2 KDEL motif containing 2 2 2
MIRT674586 SLC35B4 solute carrier family 35 member B4 2 2
MIRT675001 STRN3 striatin 3 2 2
MIRT679018 MTMR10 myotubularin related protein 10 2 2
MIRT679680 STAT3 signal transducer and activator of transcription 3 2 2
MIRT682833 FLG2 filaggrin family member 2 2 2
MIRT682886 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT683442 AP3B2 adaptor related protein complex 3 beta 2 subunit 2 2
MIRT687040 RNF115 ring finger protein 115 2 2
MIRT691957 RHOH ras homolog family member H 2 2
MIRT694625 ZFPM1 zinc finger protein, FOG family member 1 2 2
MIRT695637 SLC26A2 solute carrier family 26 member 2 2 2
MIRT697640 WRN Werner syndrome RecQ like helicase 2 2
MIRT702009 MIDN midnolin 2 2
MIRT702034 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT704789 CDK6 cyclin dependent kinase 6 2 2
MIRT705728 AMMECR1L AMMECR1 like 2 2
MIRT705879 ADM adrenomedullin 2 2
MIRT706220 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT708418 CERS4 ceramide synthase 4 2 2
MIRT709114 C3orf18 chromosome 3 open reading frame 18 2 2
MIRT709595 ITPA inosine triphosphatase 2 2
MIRT710945 MRPL45 mitochondrial ribosomal protein L45 2 2
MIRT712345 NLN neurolysin 2 2
MIRT712530 CYTH2 cytohesin 2 2 2
MIRT714019 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT717287 ARMC12 armadillo repeat containing 12 2 2
MIRT717733 FGF1 fibroblast growth factor 1 2 2
MIRT718083 CLIC5 chloride intracellular channel 5 2 2
MIRT718562 MUC20 mucin 20, cell surface associated 2 2
MIRT721639 MYLK3 myosin light chain kinase 3 2 2
MIRT722632 C8A complement C8 alpha chain 2 2
MIRT723177 CDCA4 cell division cycle associated 4 2 2
MIRT725523 FAM229B family with sequence similarity 229 member B 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-500b Methotrexate 126941 NSC740 approved resistant cell line (W1)
hsa-miR-500b-3p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-500b-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-500b-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-500b-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-500b-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-500b-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)

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